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Property:Exclusion criteria

From CAMIH

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S
Patients with maligancies of GIT, nausea and vomiting due to reasons other than chemotherapy, hypertension and renal or liver insufficiency  +
People with metastases outside the abdominal area; bad general condition (Karnofsky index < 50%); previous immunosuppressive treatment; current pregnancy; older than 75 years or younger than 18 years; known WOBE-MUGOS intolerance  +
Patients with cancer who reported no anxiety on the VAS were excluded. Patients who had surgery within the past six weeks, open skin wounds on their feet, a foot tumor or foot metastasis, or radiation treatment to the feet also were excluded. Patients who received radiation to the site of pain were excluded. Patients with dementia or peripheral neuropathy also were excluded to ensure their responses were accurate. Patients who had recent surgery were excluded to differentiate chronic cancer- related pain from acute surgical pain  +
Patients were excluded if they had had surgery in the previous six weeks or had open skin wounds on the feet, foot tumors or foot metastases, radiation to the feet, radiation to the site of pain, or more than 50% loss of feeling because of peripheral neuropathy. Patients with symptoms of deep vein thrombosis required a medical consultation prior to study participation or prior to continuation in the study if symptoms developed during the study.  +
Enteral or parenteral nutrition; had taken; taken anabolic agents, gestagens, cannabinoids, or corticosteroids within the past month; significant cause of secondary anorexia or psychiatric disorder (substance abuse or schizophrenia)  +
Neuropathy caused by other antineoplastic treatment except paclitaxel, cisplatin or vinblastine; pre-existing diabetes mellitus and/or neuropathy caused by vitamin deficiency, infection, trauma, poisoning, oppression, ischemia, metabolic disorders; genetic neuropathy and/or peripheral sensory nerve dysfunction due to central nervous system lesions; use of other drug therapy for neuropathy in the last 30 days (such as nerve growth factor, amifostine reduced glutathione, vitamin E or B, glucocorticoids, ethosuximide, carbamazepine, gabapentin, sodium thiosulfate, glutamic acid, lamotrigine, α-fatty acid, lithium salt, lithium salt or magnesium salt); participation in other clinical trials in the past 30 days; out of control clinical problems (such as serious mental, nerve, cardiovascular and/or respiratory system disease); pregnant or lactating women; and poor compliance. During the trial, patients were withdrawn if serious adverse events occurred, and/or the patient became pregnant.  +
T
Contraindications of surgery; long-term administration of medication, recent administration of glucocorticoids, antibiotics, or anodyne; recurrent pericoronitis of the impacted tooth; moderate caries of the wisdom tooth and adjacent teeth; periapical periodontitis, pulpitis, or periodontitis  +
Pregnancy or lactation, nausea or vomiting prior to chemotherapy administration, presence of conditions that may cause nausea or vomiting (e.g., brain metastasis, bowel obstruction, hepatitis, or recent abdominal or pelvic irradiation within 1 week), bleeding diathesis, allergy to ginger, or concomitant treatment with other chemotherapy.  +
- Cancer treated by chemotherapy - Previous invasive cancer at any side - Patients over 70 years (due to expected increasing prevalence of competing causes of death and potential low contribution to follow-up)  +
History of chronic pain, disseminated cancer, narcotic or ethanol addiction, peripheral neuropathy, foot amputation, diagnosed deep vein thrombosis, open wound on foot, dementia, or psychiatric diagnoses.  +
U
Patients treated previously for any other malignancies by chemotherapy and/or radio-therapy, other head and neck cancers, patients with xerostomia because of any other reasons, other systemic disorders, patients with any deleterious habits, and patients on medications such as anticholinergics, anti-histaminics, drugs causing xerostomia, and other known radioprotective agents, and patients who received 131I other than 100 mCi doses  +
Tumors that were not resectable by surgery, serious post-operative complications before starting supplementation, pathological diagnosis other than epithelial carcinoma (such as malignant lymphoma and sarcoma), and pathological stage 0 or IV  +
Patients using other gingers or the other antiemetic medication such as NK1 receptor antagonist or long-acting 5HT3 receptor antagonists to current study treatment; patients with gut obstruction or brain or bowel metastasis, patients using anticoagulant medication, and patients with allergy to ginger  +
People who had other types of cancer, whose cancer recurred before the treatment, who had mental and psychiatric diseases, and who had contraindications for foot massage (such as disseminated edema, a pacemaker, a history of myocardial infarction, uncontrolled hypertension, active gout, deep vein thrombosis history, gallbladder or kidney stones, acute infection, fever, or a fracture or wound on the feet)  +
V
Patients with recurrent disease, synchronous multiple tumors, previous malignant disease, abnormal liver or renal function, hypertriglyceridemia, hypercholesterolemia, diabetes mellitus, hypertension, and recent or active peptic ulcer  +
Patients with Karnofsky Performance Status >2, previous exposure to neurotoxic therapies, and/or risk factors for neuropathy onset (diabetes mellitus, chronic alcoholism)  +