Property:Exclusion criteria
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S
Sontakke et al. (2003): Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: A randomized, cross-over, double blind study +
Patients with maligancies of GIT, nausea and vomiting due to reasons other than chemotherapy, hypertension and renal or liver insufficiency +
Stauder et al. (1991): Strahlentherapeutische Nebenwirkungen bei Abdominalkrebspatienten und deren Reduktion durch hydrolytische Enzyme +
People with metastases outside the abdominal area; bad general condition (Karnofsky index < 50%); previous immunosuppressive treatment; current pregnancy; older than 75 years or younger than 18 years; known WOBE-MUGOS intolerance +
Stendell-Hollis et al. (2010): Green tea improves metabolic biomarkers, not weight or body composition: a pilot study in overweight breast cancer survivors +
NI +
Stephenson et al. (2000): The Effects of Foot Reflexology on Anxiety and Pain in Patients With Breast and Lung Cancer. +
Patients with cancer who reported no anxiety on the VAS were excluded. Patients who had surgery within the past six weeks, open skin wounds on their feet, a foot tumor or foot metastasis, or radiation treatment to the feet also were excluded. Patients who received radiation to the site of pain were excluded. Patients with dementia or peripheral neuropathy also were excluded to ensure their responses were accurate. Patients who had recent surgery were excluded to differentiate chronic cancer- related pain from acute surgical pain +
Patients were excluded if they had had surgery in the previous six weeks or had open skin wounds on the feet, foot tumors or foot metastases, radiation to the feet, radiation to the site of pain, or more than 50% loss of feeling because of peripheral neuropathy. Patients with symptoms of deep vein thrombosis required a medical consultation prior to study participation or prior to continuation in the study if symptoms developed during the study. +
Strasser et al. (2006): Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled (…) +
Enteral or parenteral nutrition; had taken; taken anabolic agents, gestagens, cannabinoids, or corticosteroids within the past month; significant cause of secondary anorexia or psychiatric disorder (substance abuse or schizophrenia) +
Stratton et al. (2010): Oral Selenium Supplementation Has No Effect on Prostate- Specific Antigen Velocity in Men Undergoing Active Surveillance for Localized Prostate Cancer +
NI +
Su et al. (2004): Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms +
Patients who are unable to complete the study questionnaires. +
Sun et al. (2016): A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy +
Neuropathy caused by other antineoplastic treatment except paclitaxel, cisplatin or vinblastine; pre-existing diabetes mellitus and/or neuropathy caused by vitamin deficiency, infection, trauma, poisoning, oppression, ischemia, metabolic disorders; genetic neuropathy and/or peripheral sensory nerve dysfunction due to central nervous system lesions; use of other drug therapy for neuropathy in the last 30 days (such as nerve growth factor, amifostine reduced glutathione, vitamin E or B, glucocorticoids, ethosuximide, carbamazepine, gabapentin, sodium thiosulfate, glutamic acid, lamotrigine, α-fatty acid, lithium salt, lithium salt or magnesium salt); participation in other clinical trials in the past 30 days; out of control clinical problems (such as serious mental, nerve, cardiovascular and/or respiratory system disease); pregnant or lactating women; and poor compliance.
During the trial, patients were withdrawn if serious adverse events occurred, and/or the patient became pregnant. +
T
Tan et al. (2018): Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor +
Contraindications of surgery; long-term administration of medication, recent administration of glucocorticoids, antibiotics, or anodyne; recurrent pericoronitis of the impacted tooth; moderate caries of the wisdom tooth and adjacent teeth; periapical periodontitis, pulpitis, or periodontitis +
Thamlikitkul et al. (2017): Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study +
Pregnancy or lactation, nausea or vomiting prior to chemotherapy administration, presence of conditions that may cause nausea or vomiting (e.g., brain metastasis, bowel obstruction, hepatitis, or recent abdominal or pelvic irradiation within 1 week), bleeding diathesis, allergy to ginger, or concomitant treatment with other chemotherapy. +
Togni et al. (2015): Clinical evaluation of safety and efficacy of Boswellia-based cream for prevention of adjuvant radiotherapy skin damage in mammary carcinoma: a randomized placebo controlled trial +
Radical mastectomy +
Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial +
- Cancer treated by chemotherapy
- Previous invasive cancer at any side
- Patients over 70 years (due to expected increasing prevalence of competing causes of death and potential low contribution to follow-up) +
Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. +
History of chronic pain, disseminated cancer, narcotic or ethanol addiction, peripheral neuropathy, foot amputation, diagnosed deep vein thrombosis, open wound on foot, dementia, or psychiatric diagnoses. +
U
Upadhyaya et al. (2017): Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differential thyroid cancer: A randomized-controlled trial +
Patients treated previously for any other malignancies by chemotherapy and/or radio-therapy, other head and neck cancers, patients with xerostomia because of any other reasons, other systemic disorders, patients with any deleterious habits, and patients on medications such as anticholinergics, anti-histaminics, drugs causing xerostomia, and other known radioprotective agents, and patients who received 131I other than 100 mCi doses +
Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial +
Tumors that were not resectable by surgery, serious post-operative complications before starting supplementation, pathological diagnosis other than epithelial carcinoma (such as malignant lymphoma and sarcoma), and pathological stage 0 or IV +
Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study +
Patients using other gingers or the other antiemetic medication such as NK1 receptor antagonist or long-acting 5HT3 receptor antagonists to current study treatment; patients with gut obstruction or brain or bowel metastasis, patients using anticoagulant medication, and patients with allergy to ginger +
Uysal et al. (2016): Effects of foot massage applied in two different methods on symptom control in colorectal cancer patients: Randomised control trial +
People who had other types of cancer, whose cancer recurred before the treatment, who had mental and psychiatric diseases, and who had contraindications for foot massage (such as disseminated edema, a pacemaker, a history of myocardial infarction, uncontrolled hypertension, active gout, deep vein thrombosis history, gallbladder or kidney stones, acute infection, fever, or a fracture or wound on the feet) +
V
Van Zandwijk et al. (2000): EUROSCAN, a Randomized Trial of Vitamin A and N-Acetylcysteine in Patients With Head and Neck Cancer or Lung Cancer +
Patients with recurrent disease, synchronous multiple tumors, previous malignant disease, abnormal liver or renal function, hypertriglyceridemia, hypercholesterolemia, diabetes mellitus, hypertension, and recent or active peptic ulcer +
Villani et al. (2016): Vitamin E neuroprotection against cisplatin ototoxicity: Preliminary results from a randomized, placebo-controlled trial +
Patients with Karnofsky Performance Status >2, previous exposure to neurotoxic therapies, and/or risk factors for neuropathy onset (diabetes mellitus, chronic alcoholism) +