Property:Drop-out reasons
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Kottschade et al. (2011): The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase 3 clinical trial +
Before randomization: n=7 cancelled, n=4 ineligible
During study: n=18 refused further treatment, n=3 adverse events, n=4 alternate treatment, n=4 other medical problems, n=3 other reasons, n=1 died on study +
Kottschade et al. (2011): The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase 3 clinical trial +
Before randomization: n=4 cancelled, n=3 ineligible
During study: n=11 refused further treatment, n=8 adverse events, n=2 alternate treatment, n=2 other medical problems, n=6 other reasons +
Koyama et al. (2017): Intravenous Carnitine Administration in Addition to Parenteral Nutrition With Lipid Emulsion May Decrease the Inflammatory Reaction in Postoperative Surgical Patients +
NA +
Koyama et al. (2017): Intravenous Carnitine Administration in Addition to Parenteral Nutrition With Lipid Emulsion May Decrease the Inflammatory Reaction in Postoperative Surgical Patients +
NA +
Kraft et al. (2012): L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial +
Reasons not seperated by arm:
11x deceased, 9x other illness, 8x nausea, 5x excessive demands, 2x diarrhea, 7x other reasons, 2x Omega-3-FA intake, 1x uncooperative behavior when taking carnitine on the part of the patient
Drop-out rates and reasons: No difference between arms. +
Kraft et al. (2012): L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial +
Reasons not seperated by arm:
11x deceased, 9x other illness, 8x nausea, 5x excessive demands, 2x diarrhea, 7x other reasons, 2x Omega-3-FA intake, 1x uncooperative behavior when taking carnitine on the part of the patient
Drop-out rates and reasons: No difference between arms. +
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Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer +
Did not receive allocated intervention (not to accept contributing): n=1
Lost to follow-up: discontinued tablets (n=1); discontinued radiation due to individual preferences: n=4
Inconsistencies in the number of drop-outs in the selenium arm: flowchart reports analyzed n=33 from n=42, but only reports drop-out reasons for n=6 (reasons missing n=3); table of baseline characteristics reports data of n=37 +
Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer +
Did not receive allocated intervention (not to accept contributing): n=4
Lost to follow-up: discontinued radiation due to individual preferences: n=4 +
Li et al. (2018): Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial +
Lack of compliance (n=2) +
Li et al. (2018): Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial +
Lack of compliance (n=4) +
Lian et al. (2014): Comparing the Effectiveness of Green Tea versus Topical Metronidazole Powder in Malodorous Control of Fungating Malignant Wounds in a Controlled Randomised Study +
Death due to advanced cancer on day 5 +
Lian et al. (2014): Comparing the Effectiveness of Green Tea versus Topical Metronidazole Powder in Malodorous Control of Fungating Malignant Wounds in a Controlled Randomised Study +
NA +
Lichtmann et al. (2018): Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain +
Side effects (n=40); consent withdrawn (n=18); death (n=27) +
Lichtmann et al. (2018): Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain +
Side effects (n=35); consent withdrawn (n = 13); death (n=27) +
Lin et al. (2006): Zinc supplementation to improve mucositis and dermatitis in patients after radiotherapy for head-and-neck cancers: a double-blind, randomized study +
Voluntary withdrawal +
Lin et al. (2006): Zinc supplementation to improve mucositis and dermatitis in patients after radiotherapy for head-and-neck cancers: a double-blind, randomized study +
Voluntary withdrawal +
Lin et al. (2008): Effects of zinc supplementation on clinical outcomes in patients receiving radiotherapy for head and neck cancers: a double-blinded randomized study +
Voluntary withdrawal +
Lin et al. (2008): Effects of zinc supplementation on clinical outcomes in patients receiving radiotherapy for head and neck cancers: a double-blinded randomized study +
Voluntary withdrawal +