Property:Specifications on analyses
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Walsh et al. (2010): Use of alpha,25-dihydroxyvitamin D3 treatment to stimulate immune infiltration into head and neck squamous cell carcinoma +
The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study. +
Watanabe et al. (2010): Polaprezinc prevents oral mucositis associated with radiochemotherapy in patients with head and neck cancer +
The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study. +
Williams et al. (1996): Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity +
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Wrbka et al. (1987): Unterstützung der Chemotherapie inoperabler Karzinome durch proteolytische Fermente +
The specific analysis method is not stated in the study, however, according to the authors, all included patients were evaluated at the end of the study +
Wyatt et al. (2012): Health-Related Quality-of-Life Outcomes: A Reflexology Trial With Patients With Advanced-Stage Breast Cancer +
Chi-square test +
Wyatt et al. (2017): A Randomized Clinical Trial of Caregiver-Delivered Reflexology for Symptom Management During Breast Cancer Treatment +
All statistical tests were two sided. +
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Yap et al. (2017): Predictors of hand-foot syndrome and pyridoxine for prevention of capecitabine-induced hand-foot syndrome: a randomized clinical trial +
The incidence of grade 2 or higher HFS was compared using a χ2 test; time to onset was estimated using the Kaplan-Meier method and compared using a log-rank test, and QoL was analyzed using ANOVA for the EQ-5D OHS and χ2
tests for each of the 5 dimensions of the EQ descriptive system.
Logistic regression was used to estimate the odds of HFS (grade ≥2 vs <2) with respect to clinical characteristics. The exact procedure was used when quasiseparation was detected. All covariates were included in multivariate analysis with a stepwise selection process using significance levels of 0.1. Interaction between treatment and covariates suggested by the stepwise procedure was explored. Alternative models were assessed in terms of discrimination and calibration respectively using the c-index and the Akaike Information criterion (AIC). +
T-test and Fisher´s exact test for comparing the 2 arms
For examine differences in the profile of the diseases: Kruskal-Wallis and Chi-square test were applied +
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Zalat et al. (2020): Evaluation of the cardioprotective effects of l-carnitine and silymarin in cancer patients receiving anthracycline-containing chemotherapy +
Data are expressed as the mean value (± standard deviation). One-way analysis of variance test (one-way ANOVA) followed by LSD post hoc test was used to assess any significant difference between the three groups. Paired t-test was used to assess any significant difference within each group at baseline and after chemotherapy. All probability values presented were two-tailed and p ≤ 0.05 was considered statistically significant. +
Zick et al. (2008): Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting +
Kruskal–Wallis statistics for continuous variables and Pearson’s chi-square and Fisher exact tests, as appropriate, for categorical variables.
Cochran Mantel–Haenszel tests between treatment arms. +
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Özdelikara et al. (2017): The Effect of Reflexology on Chemotherapy-induced Nausea, Vomiting, and Fatigue in Breast Cancer Patients +
t-test +
Özdelikara et al. (2017): The effect of reflexology on the quality of life with breast cancer patients +
Univariate statistical analysis techniques, including frequency distributions, mean scores and also t tests, were also utilized for the analysis of the data. +