Property:Dosage and regime
This is a property of type Text.
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Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia +
Oral, 320mg daily MA or 500mg daily MPA
Duration: 4 month +
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia +
Oral, 2.2g EPA daily + 2g/daily Resource Support
Duration: 4 month +
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia +
Oral, 320mg daily MA or 500mg daily MPA
Oral, 2.2g EPA daily + 2g/daily Resource Support
Oral, 2x 2g daily L-Carnitine
Oral, 2x 100mg daily Thalidomid
Duration: 4 month +
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia +
Oral, 2x 2g daily
Duration: 4 month +
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia +
Oral, 2x 100mg daily
Duration: 4 month +
Margalit et al. (2012): Beta-carotene Antioxidant Use During Radiation Therapy and Prostate Cancer Outcome in the Physicians’ Health Study +
Placebo orally every 2nd day, start at the time of radiation therapy, mean (range) follow-up: 10.5 years (0.3-27.2)
+ "6% of participants in the placebo group reported taking supplemental beta-carotene or vitamin A" +
Margalit et al. (2012): Beta-carotene Antioxidant Use During Radiation Therapy and Prostate Cancer Outcome in the Physicians’ Health Study +
Beta-carotene 50mg orally every 2nd day, start at the time of radiation therapy, mean (range) follow-up: 10.5 years (0.3-27.2) +
Margalit et al. (2012): Beta-carotene Antioxidant Use During Radiation Therapy and Prostate Cancer Outcome in the Physicians’ Health Study +
NI +
Martin et al. (2002): Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial +
3x4 capsules of of WOBE-MUGOS containing each 100 mg papain (270 FIPE), 40 mg trypsin (29 ukat) and 40 mg chymotrypsin (200 ukat) daily, starting 3 days before irradiation and finishing on the last day of radiotherapy
+ all patients: radiation using a four-field box technique with individually shaped blocks; external beam radiotherapy was given using fractionation of 5 x 1.8 Gy weekly to a total dose of 50.4 Gy, specified at the isocentre +
Martin et al. (2002): Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial +
3x4 capsules without any enzyme contentsdaily, starting 3 days before irradiation and finishing on the last day of radiotherapy
+ all patients: radiation using a four-field box technique with individually shaped blocks; external beam radiotherapy was given using fractionation of 5 x 1.8 Gy weekly to a total dose of 50.4 Gy, specified at the isocentre +
Marucci et al. (2017): Double-blind randomized phase III study comparing a mixture of natural agents versus placebo in the prevention of acute mucositis during chemoradiotherapy for head and neck cancer +
Placebo mouthwash with the same colour, taste and density in identical 200mL bottles, with honey.
Rinsing with 7ml of mouthwash 4 times per day (before each main meal and radiotherapy session) during week
days, and 3 times per day (before each main meal) during weekends
+all patients: concomitant chemoradiotherapy (daily treatment, 5 times per week, for 6-6.5 weeks)
+ dental and nutritional evaluation before treatment +
Marucci et al. (2017): Double-blind randomized phase III study comparing a mixture of natural agents versus placebo in the prevention of acute mucositis during chemoradiotherapy for head and neck cancer +
Faringel Herbal mouthwash (propolis, aloe, calendula, camomile)
Rinse with 7mL of mouthwash 4 times per day (before each main meal and radiotherapy session) during week
days, and 3 times per day (before each main meal) during weekend
+all patients: concomitant chemoradiotherapy (daily treatment, 5 times per week, for 6-6.5 weeks)
+ dental and nutritional evaluation before treatment +
Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial +
Daily dose 4x300mg ginger capsules (standardized extract), with meals, per cycle for 5 days, starting on the day of chemotherapy over 3 cycles
+ Antiemetics (for 3 chemotherapy cycles, duration: day of chemo to 5 days post chemo) +
Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial +
Placebo capsules with meals, per cycle for 5 days, starting on the day of chemotherapy over 3 cycles
+ Antiemetics (for 3 chemotherapy cycles, duration: day of chemo to 5 days post chemo) +
Mayne et al. (2001): Randomized Trial of Supplemental beta-Carotene to Prevent Second Head and Neck Cancer +
One capsule per day orally for the duration of the study, median (range) follow-up: 51.1 (30-90) months +
Mayne et al. (2001): Randomized Trial of Supplemental beta-Carotene to Prevent Second Head and Neck Cancer +
50mg per day orally for the duration of the study, median (range) follow-up: 51.1 (30-90) months +
Mazdak et al. (2012): Vitamin E reduces superficial bladder cancer recurrence: A randomized controlled Trial +
NA +
Mazdak et al. (2012): Vitamin E reduces superficial bladder cancer recurrence: A randomized controlled Trial +
Oral, 400IU, 1x daily +
Meyskens et al. (1995): Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial +
- 50,000 IU/day, orally for the duration of the study, median (range) follow-up: 76 (37-111) months
- adjustments of vitamin A dosage made in relation to side effects and serum vitamin A levels +