Property:Dosage and regime
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Minchom et al. (2014): An unblinded, randomised phase II study of platinum-based chemotherapy with vitamin B12 and folic acid supplementation in the treatment of lung cancer with plasma homocysteine blood levels as a biomarker of (...) +
Vit.B12: intramuscular, 1mg, before treatment and every 9 weeks until 3 weeks after last dose of chemotherapy
Folic acid: oral, 400μg daily, start at least day seven days prior to chemotherapy, duration up to 3 weeks after chemotherapy +
Minchom et al. (2014): An unblinded, randomised phase II study of platinum-based chemotherapy with vitamin B12 and folic acid supplementation in the treatment of lung cancer with plasma homocysteine blood levels as a biomarker of (...) +
No further treatment +
Mix et al. (2015): Randomized phase II trial of selenomethionine as a modulator of efficacy and toxicity of chemoradiation in squamous cell carcinoma of the head and neck +
Selenomethionine 3600 µg/m²(in 800 µg tablets) 2x daily 7 days before chemotherapy, during chemotherapy 1x daily, and daily for 3 weeks after chemotherapy +
Mix et al. (2015): Randomized phase II trial of selenomethionine as a modulator of efficacy and toxicity of chemoradiation in squamous cell carcinoma of the head and neck +
2x daily 7 days before chemotherapy, during chemotherapy 1x daily, and daily for 3 weeks after chemotherapy +
Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy +
Oral, day 0 chemotherapy: 500 µg 3x daily
Duration: until 1 month after the end of chemotherapy +
Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy +
Day 0 chemotherapy: 250 mg 1x daily
Duration: 7 days in each chemotherapy cycle +
Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy +
Day 2 chemotherapy: 10 mg 3x daily
Duration: Day 2 to Day 5 in each chemotherapy cycle +
Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy +
Day 0 of chemotherapy: 400 mg 1x daily
Duration: until 1 month after the end of chemotherapy +
Montazeri et al. (2013): Effect of Herbal Therapy to Intensity Chemotherapy-Induced Nausea and Vomiting in Cancer Patients +
4x 250mg ginger capsule (production not standardized)
Start: 2 capsules 30 minutes before the start of chemo, 2 capsules 6 hours after the end cross-over after cycle +
Montazeri et al. (2013): Effect of Herbal Therapy to Intensity Chemotherapy-Induced Nausea and Vomiting in Cancer Patients +
4x 250mg ginger capsule (production not standardized)
Start: 2 capsules 30 minutes before the start of chemo, 2 capsules 6 hours after the end cross-over after cycle +
Moslemi et al. (2014): Oral zinc sulphate and prevention of radiation-induced oropharyngealmucositis in patients with head and neck cancers: A double blind, randomized controlled clinical trial +
Capsules filled with starch and designed same medicine firm, form and color to zinc sulphate, three times daily at 8 hours interval,
Duration of intervention: started 10 days before beginning of treatment and continued to 8 weeks after the end of treatment +
Moslemi et al. (2014): Oral zinc sulphate and prevention of radiation-induced oropharyngealmucositis in patients with head and neck cancers: A double blind, randomized controlled clinical trial +
Zinc sulphate capsules (30 mg) three times daily at 8 hours interval,
Duration of intervention: started 10 days before beginning of treatment and continued to 8 weeks after the end of treatment +
Muecke et al. (2010): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology +
NA +
Muecke et al. (2010): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology +
500 µg selenium in the form of sodium selenite (selenase®), orally on radiotherapy days and 300 µg on days without radiotherapy +
Muecke et al. (2013): Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology-a subgroup analysis of a multicenter, phase III trial +
NA +
Muecke et al. (2013): Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology-a subgroup analysis of a multicenter, phase III trial +
500 µg selenium in the form of sodium selenite [selenase®), orally on radiotherapy days and 300 µg on days without radiotherapy +
Muecke et al. (2014): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology: follow-up analysis of the survival data 6 years after cessation of randomization +
500 µg selenium in the form of sodium selenite [selenase®), orally on radiotherapy days and 300 µg on days without radiotherapy +
Muecke et al. (2014): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology: follow-up analysis of the survival data 6 years after cessation of randomization +
NA +
N
Najafizade et al. (2013): Preventive effects of zinc sulfate on taste alterations in patients under irradiation for head and neck cancers: A randomized placebo-controlled trial +
Zinc sulfate capsules: 50 mg, three times a day, after meals,
Duration of intervention: started with beginning of radiotherapy and continued one month after completion of irradiation +
Najafizade et al. (2013): Preventive effects of zinc sulfate on taste alterations in patients under irradiation for head and neck cancers: A randomized placebo-controlled trial +
Capsules three times a day, after meals,
Duration of intervention: started with beginning of radiotherapy and continued one month after completion of irradiation +