Property:Outcome specification
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Lin et al. (2008): Effects of zinc supplementation on clinical outcomes in patients receiving radiotherapy for head and neck cancers: a double-blinded randomized study +
Time from the first day of treatment to death +
Lin et al. (2008): Effects of zinc supplementation on clinical outcomes in patients receiving radiotherapy for head and neck cancers: a double-blinded randomized study +
More specifically: LFS (Local-Free Survival), from the date of the first treatment until the date local tumor progression was documented +
Lin et al. (2008): Effects of zinc supplementation on clinical outcomes in patients receiving radiotherapy for head and neck cancers: a double-blinded randomized study +
More specifically: MFS (Metastases-Free Survival), from the date of the first treatment until the date distant metastases occurred +
Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis +
Between the time of first treatment and the time of local recurrence or distant metastases;
Subgroup analysis: no significant difference between the arms for the 5-year DFS among the patients with stages III to IV head and neck cancers other than nasopharyngeal carcinoma (p = .752) +
Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis +
? +
Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis +
The period between the time of treatment and the time of death;
Subgroup analysis: no significant difference between the arms for the 5-year OS among the patients with stages III to IV head and neck cancers other than nasopharyngeal carcinoma (p = .357) +
Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis +
Serum transferrin level +
Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis +
More specifically: MFS (Metastases-Free Survival), between the time of the first treatment and the time when distant metastases occurred +
Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis +
More specifically: LFS (Local-Free Survival), between the time of the first treatment and the time when local tumor progression was documented +
Lin et al. (2010): Discrepancy of the effects of zinc supplementation on the prevention of radiotherapy-induced mucositis between patients with nasopharyngeal carcinoma and those with oral cancers: subgroup analysis of a double-blind, randomized study +
NI +
Lin et al. (2010): Discrepancy of the effects of zinc supplementation on the prevention of radiotherapy-induced mucositis between patients with nasopharyngeal carcinoma and those with oral cancers: subgroup analysis of a double-blind, randomized study +
NI +
Lissoni et al. (1998): Biotherapy with the Pineal Immunomodulating Hormone Melatonin versus Melatonin plus Aloe vera in Untreatable Advanced Solid Neoplasms +
The clinical response was evaluated according to WHO criteria, by repeating the radiological examinations at 2-month intervals.
WHO Gradiations:
Complete response
Partial response
Stable disease
Disease control
Progressive disease +
Lissoni et al. (2009): A Randomized Study of Chemotherapy versus Biochemotherapy with Chemotherapy plus Aloe arborescens in Patients with Metastatic Cancer +
The clinical response and toxicity were assessed according to WHO criteria. The clinical responses were radiologically evaluated after at least three cycles of chemotherapy by repeating the same radiological investigation used prior to the onset of chemotherapy, including CT scan, NMR and PET.
Gradations:
Complete response
Partial response
Stable disease
Disease control
Progressive disease +
Lissoni et al. (2009): A Randomized Study of Chemotherapy versus Biochemotherapy with Chemotherapy plus Aloe arborescens in Patients with Metastatic Cancer +
Toxicity was assessed according to WHO criteria. Patients were monitored weekly by routine laboratory tests. The
evaluation of subjective symptoms, such as fatigue and asthenia, was assessed by an individual report. +
Liu et al. (2010): Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial +
Salivary activity +
Liu et al. (2010): Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial +
Salivary cumulated activities in first 24h after 131I ingestion divided by total cumulated activities +
Liu et al. (2010): Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial +
Salivary absorbed sose, calculated from the 131I activity administered, saliva retention time and salivary gland mass (determined by CT) +
Liu et al. (2010): Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial +
Salivary absorbed dose during the first 24 h after 131I ingestion, calculated from the 131I activity administered, saliva retention time and salivary gland mass (determined by CT) +
Lua et al. (2015): Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer +
Influence of CINV on health-related quality of life at T0 (Baseline), T6 (Day 8 of chemotherapy) with regard to physical, role, emotional, cognitive and social function, fatigue, nausea/vomiting, pain, dyspnea, insomnia, loss of appetite, constipation, diarrhea, financial difficulties +
Lua et al. (2015): Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer +
Severity of nausea, incidence of vomiting ( day 1 of chemotherapy to day 5 of chemotherapy) +