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Property:Outcome specification

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Renal toxicity: glomerular filtration rate cc/min (start of the study, day 7 of chemotherapy, day 21 of chemotherapy)  +
Renal toxicity: serum creatinine mg/dL (start of the study, day 7 of chemotherapy, day 21 of chemotherapy)  +
Renal toxicity: urea mg/dL (start of the study, day 7 of chemotherapy, day 21 of chemotherapy)  +
The patients’ mouths were examined for stomatitis by two assistants on days 1, 3, 5, 7, and 14 with WHO stomatitis intensity survey checklist: 0 = no stomatitis 1 = represents pain and erythema without wounds 2 = refers to the case where wound and erythema exist, but the patient is able to eat solid food 3 = is existence of extensive wound and erythema and inability to eat solid food 4 = mucosal bleeding, extensive inflammation, and complete inability to eat and drink  +
The patients were asked to report their pain intensity by VAS, a 10cm ruler in which zero shows no pain and 10 represents intolerable pain.  +
Total daily physical activity and the associated energy expenditure SenseWear PRO<sub>2</sub> wristband: able to assess total energy expenditure (TEE), that is, the sum of REE plus the energy spent in physical activity (active energy expenditure [AEE]), which is able to identify the specific type of physical activity (e.g., walking, running, lying down) in such a wayastoattribute to it a “functional quality”  +