Property:Dosage and regime
This is a property of type Text.
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Su et al. (2004): Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms +
The aloe vera solution consisted of 94.5% aloe juice, 5.0% pear juice concentrate, 0.4% lemon-lime flavor, and 0.1% citric acid.
Patients were instructed to take a 20ml swish and swallow 4x daily, beginning on the first day and continuing
throughout the RT course.
+ all patients were instructed to alleviate oral discomfort by rinsing daily with a baking soda mouth rinse, and swishing and swallowing Benadryl and nystatin combination mouthwashes and viscous lidocaine, as needed
+ all patients: radiation dose 50-70 Gy at 1.8-2 Gy per day +
Su et al. (2004): Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms +
The aloe vera solution consisted of 94.5% water, 5.0% pear juice concentrate, 0.4% lemon-lime flavor, and 0.1% citric acid.
Patients were instructed to take a 20ml swish and swallow 4x daily, beginning on the first day and continuing
throughout the RT course.
+ all patients were instructed to alleviate oral discomfort by rinsing daily with a baking soda mouth rinse, and swishing and swallowing Benadryl and nystatin combination mouthwashes and viscous lidocaine, as needed
+ all patients: radiation dose 50-70 Gy at 1.8-2 Gy per day +
Sun et al. (2016): A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy +
Lactose, 3 x 1000 mg
Duration: 8 weeks +
Sun et al. (2016): A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy +
Oral, 3 x 1000 mg daily (in two 500 mg tablets)
Duration: 8 weeks +
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Tan et al. (2018): Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor +
Oral intake of 3 x 30,000 units of enteric-coated capsules of bromelain daily, starting one day before the surgery up to and including three days after the surgery
+ all patients: sugery: third molar extraction was performed under local anesthesia +
Tan et al. (2018): Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor +
Cold-hot compress for two days after surgery
+ all patients: surgery: third molar extraction was performed under local anesthesia +
Thamlikitkul et al. (2017): Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study +
500-mg placebo twice a day for 5 days starting on the first day of the second chemotherapy cycle;
Antiemetics: Ondansetron + Dexamethason;
Crossover in cycle 3 +
Thamlikitkul et al. (2017): Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study +
Daily dose 2x500mg ginger capsule (dried ginger powder) for 5 days, starting 30min before second chemotherapy cycle;
Antiemetics: Ondansetron + Dexamethason;
Crossover in cycle 3 +
Togni et al. (2015): Clinical evaluation of safety and efficacy of Boswellia-based cream for prevention of adjuvant radiotherapy skin damage in mammary carcinoma: a randomized placebo controlled trial +
Applied directly after radiotherapy and in the evening or on treatment-free days in the morning and evening +
Togni et al. (2015): Clinical evaluation of safety and efficacy of Boswellia-based cream for prevention of adjuvant radiotherapy skin damage in mammary carcinoma: a randomized placebo controlled trial +
Applied directly after radiotherapy and in the evening or on treatment-free days in the morning and evening +
Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial +
NA +
Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial +
75mg daily (orally), cycles of 3 months & then 1 month break
+ dose reduction and/or discontinuation of beta-carotene if grade II toxicity (repeatedly) reported +
Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. +
The foot reflexology was initiated during the evening on postoperative day 2 while patients are on PCA and between 1 and 3 hours after a dose of pain medication, day 3 after surgery and day 4 after surgery, duration: 20 min each) +
Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. +
NA +
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Upadhyaya et al. (2017): Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differential thyroid cancer: A randomized-controlled trial +
Oral, 100mg
Duration: week -1 radioiodine treatment until week +4 (total 5 weeks) +
Upadhyaya et al. (2017): Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differential thyroid cancer: A randomized-controlled trial +
NA +
Upadhyaya et al. (2017): Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differential thyroid cancer: A randomized-controlled trial +
Oral, 200mg
Duration: week -1 radioiodine treatment until week +4 (total 5 weeks) +
Upadhyaya et al. (2017): Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differential thyroid cancer: A randomized-controlled trial +
Oral, 300mg
Duration: week -1 radioiodine treatment until week +4 (total 5 weeks) +
Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial +
Vitamin D<sub>3</sub> supplementation, 2000 IU/d, after surgery until the end of the trial +
Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial +
Placebo after surgery until the end of the trial +