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Property:Results after intervention

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Average tolerability by doctor: enzyme-arm: 1.57(0.88); control-arm: 1.38(0.86) Average tolerability by patient: enzyme-arm: 1.75(1.13); control-arm: 1.41(0.86) Therapy result by doctor: enzyme-arm: 1.94(0.79); control-arm : 1.22(0.54) Therapy result by patient: enzyme-arm: 1.89(0.85); control-arm: 1.22(0.54)  +
Mean onset in days of radiation side effects per arm Ezyme-arm: 17.3(12.3) Control-arm B: 15.6(7.7) (p=NI) Mean duration in days of radiation side effects per arm Enzyme-arm: 12.8(9.7) Control-arm: 24.6(14.2) (p=NI) Severity of side effects (score from 1 to 3) per arm: Enzyme-Arm: 1.77(0.77) Control-Arm: 1.88(0.62) (p=NI) The side effects in the enzyme-arm started later, were less severe and lasted for a shorter time compared to the side effects in the control arm.  +
No radiation-related headaches and ulcerations occurred in either arm; vomiting symptoms and oedema only occurred in the control-arm; all other symptoms occurred in both arms, but less frequently and less intensively in the enzyme-arm than in the control-arm. Deterioration of the general status in 5.5% of the enzyme-arm and in 11.4% of the control-arm, no changes of the general status in 94.5% of the enzyme-arm and 88.6% of the control-arm.  +
Single doses: The average single radiation dose was approx. 8% higher in the enzyme-arm at the beginning and approx. 4% higher after 2 and 5 weeks than in the control-arm. Total dose: After 2 weeks the total dose was about the same in both arms, after 5 weeks the difference between the enzyme-arm and the control-arm was about 16% more in the enzyme-arm.  +
Patients from the enzyme-arm got 102 additional medications, patients from the control-arm got 125 additional medications (p=NI). The duration of taking the additional medication did not differ between the two arms.  +
The average body weight in the green tea arm was reduced by 1.2 kg compared to the baseline, whereas assignment to the placebo arm was associated with a slight rise in mean body weight of 0.2 kg over the same time period. These changes were not significant (p=0.23).  +
The BMI in the green tea arm was reduced by 0.5 kg/m<sup>2</sup> after 6 month, the body fat percentage by 0.6%, the BMI in the placebo arm remained the same after 6 month , body fat percentage increased slightly by 0.4%, but these differences were not significant (p=0.22 for BMI, p=0.21 for body fat).  +