Property:Results after intervention
This is a property of type Text.
T
Togni et al. (2015): Clinical evaluation of safety and efficacy of Boswellia-based cream for prevention of adjuvant radiotherapy skin damage in mammary carcinoma: a randomized placebo controlled trial +
Significant distribution differences between the arms
Boswellia arm: more often with mild or moderate erythema (78% compared to 51% in base cream arm)
Placebo arm: more often with intense erythema (49% compared to 22% in boswellia arm)
Differences in grades of visual intensity of erythema were statistically significant
Objective assessment, Computerized photo analysis:
Significantly lower magenta color percentage in the boswellia arm (10.1%) compared to the placebo arm (13.3%)
Higher proportion of patients treated with boswellia cream scored slight intensity of erythema compared to those of base cream arm (50.0% vs 23.0%)
A lower fraction of boswellia cream arm patients scored visual intensity of erythema as intense compared to patients of the base cream arm (19.0% vs 48.6%) +
Togni et al. (2015): Clinical evaluation of safety and efficacy of Boswellia-based cream for prevention of adjuvant radiotherapy skin damage in mammary carcinoma: a randomized placebo controlled trial +
Tendency towards lower incidence/expression of superficial skin symptoms in the boswellia group compared to the placebo group, p=0.066 +
Togni et al. (2015): Clinical evaluation of safety and efficacy of Boswellia-based cream for prevention of adjuvant radiotherapy skin damage in mammary carcinoma: a randomized placebo controlled trial +
Significantly lower use of hydrocortisone in the boswellia arm (25%) compared to the placebo arm (63%), p < 0.0001 +
Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial +
'''Overall'''
- No significant differences in incidence of SPT between intervention and control arm (no p-value reported)
- Relative risks for recurrence and/or SPT not significant (no p-value reported) +
Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial +
'''Overall'''
- No significant differences in 10-year survival rate between intervention and control arm (p=0.20)
- Relative risk not significant (no p-value reported) +
Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial +
'''Overall'''
- No significant differences in 10-year DFS rate between intervention and control arm (p=0.56)
- Relative risks for DFS not significant (no p-value reported) +
Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. +
Sig. lower consumption in intervention than arm passive control (mean diff.= 39.59 mg Demerol; p= 0.015) +
Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. +
NA +
Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. +
NA +
Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. +
NA +
U
Upadhyaya et al. (2017): Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differential thyroid cancer: A randomized-controlled trial +
After 6 months:
Vitamin E 100mg: Increase EF right parotis (p < 0.01) and UI right submand. (p < 0.05)
Vitamin E 200mg: Increase UI right parotis, both Submand. (p < 0.01)
Vitamin E 300mg: Increase UF left parotis (p < 0.05) and right submand. (p < 0.01), increase UI in both submand. (p < 0.01)
Usual Care: Decreasel UF in both parotis (p < 0.01)
Rest: ns.
All arms compared:
UF: left submand.: p < 0.05
UI: right parotis: p < 0.05; both submand.: p < 0.01
ER: left parotis: p < 0.05 +
Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial +
''Overall:''
No significant differences +
Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial +
''Overall:''
No significant differences +
Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial +
''Overall:''
Subgroupanalysis: low (<20 ng/mL (n=173)), middle (20-40 ng/mL (n=232)), or high (>40 ng/mL (n=5)) serum levels of 25(OH)D at baseline
* In middle-baseline-level subgroup, 5-year relapse-free survival significantly higher in intervention arm than in placebo arm (85% vs. 71%; HR for relapse or death, 0.46; 95% CI, 0.24-0.86; p=.02)
* In low-baseline-level subgroup no significant differences
* In high-baseline-level subgroup no further analyses because of small number of patients
* Overall survival was not significantly different between the arms in both the middle subgroup and the low subgroup
Post hoc analysis:
* Cumulative incidence of relapse was not significantly different
* In the subgroup with middle baseline levels of 25(OH)D, the cumulative incidence of relapse was significantly lower in the intervention arm than in the placebo arm (subdistribution HR, 0.44; 95% CI, 0.21-0.89; p=.02)
* No significant difference for the cumulative incidence of relapse in the low-baseline-level subgroup
* Age adjusted analysis: hazard of relapse or death was significantly less in intervention arm compared with the placebo arm, with an adjusted HR of 0.66 (95% CI, 0.43-0.99; p=.048) but hazard of death was not significantly different
* Analyses adjusted for stage I disease status did not show any significant differences
* No ignificant associations for gender, age groups, body many index, site of cancer, disease stage and adenocarcinoma vs. nonadenocarcinoma +
Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study +
NA +
Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study +
NA +
Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study +
NA +
Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study +
NA +