Property:Cancer stage specification
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Kessels et al. (2017): Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma A Randomized Clinical Trial +
NI +
Khan et al. (2017): Randomized trial of vitamin D3 to prevent worsening of musculoskeletal symptoms in women with breast cancer receiving adjuvant letrozole. The VITAL trial +
Stage I–III hormone receptor positive breast cancer +
Khodabakhshi et al. (2019): Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study +
Locally advanced or metastatic breast cancer
Cancer stage, n (%) per arm:
Neo-adjuvant: intervention: 25 (83.3), comparison: 19 (63.3)
Metastasizing: intervention: 5 (16.7), comparison: 11 (36.7) +
Kirste et al. (2011): Boswellia serrata Acts on Cerebral Edema in Patients Irradiated for Brain Tumors. A Prospective, Randomized, Placebo-Controlled, Double-Blind Pilot Trial +
NI +
Konmun et al. (2017): A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy +
Patients with stage I/II/III in %
- overall: 13/41/46
- intervention arm: 22/30/48
- placebo arm: 5/51/44
Significant difference between arms (p=0.031): intervention arm with earlier stages at diagnosis of cancer when compared with the placebo arm +
Kottschade et al. (2011): The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase 3 clinical trial +
NI +
Koyama et al. (2017): Intravenous Carnitine Administration in Addition to Parenteral Nutrition With Lipid Emulsion May Decrease the Inflammatory Reaction in Postoperative Surgical Patients +
Stage I-III +
Kraft et al. (2012): L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial +
Not operable Pancreas carcinoma, stage IV +
L
Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer +
NI +
Li et al. (2018): Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial +
NI +
Lian et al. (2014): Comparing the Effectiveness of Green Tea versus Topical Metronidazole Powder in Malodorous Control of Fungating Malignant Wounds in a Controlled Randomised Study +
Hospitalised patients with malodorous fungating malignant wounds. +
Lichtmann et al. (2018): Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain +
NI +
Lin et al. (2006): Zinc supplementation to improve mucositis and dermatitis in patients after radiotherapy for head-and-neck cancers: a double-blind, randomized study +
Stages I-IV and primary and recurrent tumors +
Lin et al. (2008): Effects of zinc supplementation on clinical outcomes in patients receiving radiotherapy for head and neck cancers: a double-blinded randomized study +
Stages I-IV and primary and recurrent tumors +
Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis +
stages III (n=5) and IV (n=29) +
Lin et al. (2010): Discrepancy of the effects of zinc supplementation on the prevention of radiotherapy-induced mucositis between patients with nasopharyngeal carcinoma and those with oral cancers: subgroup analysis of a double-blind, randomized study +
Stage II-IV and recurrent cancer +
Lissoni et al. (1998): Biotherapy with the Pineal Immunomodulating Hormone Melatonin versus Melatonin plus Aloe vera in Untreatable Advanced Solid Neoplasms +
Patients with untreatable locally advanced or metastatic solid tumors and a life expectancy <6 months
Tumor histotype:
Non-small cell lung cancer: Control arm = 11; Aloe arm = 12
Gastrointestinal tract tumors: Control arm = 9; Aloe arm = 7
Breast cancer: Control arm = 4; Aloe arm = 3
Brain glioblastoma: Control arm = 2; Aloe arm = 2 +
Lissoni et al. (2009): A Randomized Study of Chemotherapy versus Biochemotherapy with Chemotherapy plus Aloe arborescens in Patients with Metastatic Cancer +
Dominant metastasis sites per arm:
Soft tissues: Aloe arm = 7; Control arm = 6
Bone: Aloe arm =20; Control arm = 16
Lung: Aloe arm =26; Control arm = 25
Liver: Aloe arm =37; Control arm = 35
Liver + lung: Aloe arm =24; Control arm = 25
Liver + peritoneum: Aloe arm =7; Control arm = 12 +
Liu et al. (2010): Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial +
pT1–T3, N0–N1, M0 +
Lua et al. (2015): Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and health-related quality of life in women with breast cancer +
Stage I: n=5
Stage II: n=35
Stage III: n=15
Stage IV: n=5 +