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- Argyriou et al. (2006): A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results + (Adult patients with a confirmed diagnosis … Adult patients with a confirmed diagnosis of solid or nonmyeloid malignancy scheduled to receive six courses of cumulative DDP-based regimens were enrolled if they had satisfactory liver and renal function, a life expectancy of at least 9 months, and a WHO performance score of 0–1.onths, and a WHO performance score of 0–1.)