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- Argyriou et al. (2006): Preventing Paclitaxel-Induced Peripheral neuropathy: A Phase 2 Trial of Vitamin E Supplementation + (Adult patients with a confirmed diagnosis … Adult patients with a confirmed diagnosis of solid or nonmyeloid malignancy scheduled to receive six courses of paclitaxel-based chemotherapy regimen were enrolled if they had satisfactory liver and renal function, a life expectancy of at least 9 months, and a WHO performance score of 0–1.onths, and a WHO performance score of 0–1.)