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- Kottschade et al. (2011): The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase 3 clinical trial + (Patients who had all gross cancer removed … Patients who had all gross cancer removed (microscopic residual disease or residual margin involvement was allowed), scheduled to undergo curative-intent chemotherapy with either taxanes or platinum compounds, have a good performance status (ECOG 0-2), life expectancy ≥6 months, and not have preexisting peripheral</br>neuropathy from any causesting peripheral neuropathy from any cause)