Property:Specifications on cancer therapies
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M
Muecke et al. (2014): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology: follow-up analysis of the survival data 6 years after cessation of randomization +
NA +
N
Najafizade et al. (2013): Preventive effects of zinc sulfate on taste alterations in patients under irradiation for head and neck cancers: A randomized placebo-controlled trial +
Al the patients were treated with daily fractions of 180 to 200 Gy lasting from 5to 9weeks, for atotal dose of 6000 to 7000 cGy. The radiation fields were the same for al patients, and the tongue was always included. +
Nasser et al. (2017): Vitamin D ointment for prevention of radiation dermatitis in breast cancer patients +
Radiation therapy to the involved breast was delivered by two tangential fields, delivered as a single fraction per day, 5 days a week;
radiation dose was either 42.72 Gy in 16 fractions or 50 Gy in 25 fractions, when indicated, a boost was provided to the tumor bed, to a total dose of 10 Gy administered in 5 fractions of 2 Gy each +
Newling et al. (1995): Tryptophan metabolites, pyridoxine (vitamin B6) and their influence on the recurrence rate of superficial bladder cancer. Results of a prospective, randomised phase III study performed by the EORTC GU Group +
Cystoscopy and resection/fulguration of all recurrences were performed every 3 months during the first year and every 6 months thereafter. +
Ng et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial +
Continuous infusion of 2400 mg/m<sup>2</sup> of 5-fluorouracil (5-FU) over 46 to 48 hours, a bolus of 400 mg/m<sup>2</sup> of 5-FU, 400 mg/m<sup>2</sup> of leucovorin, and 85 mg/m<sup>2</sup> of oxaliplatin (mFOLFOX6) plus 5 mg/kg of bevacizumab administered intravenously every 14 days per institutional standard of care (1 cycle=14 days),
bevacizumab was allowed to be omitted during the first cycle and started with cycle 2 at the investigator’s discretion +
Nguyen et al. (2012): Randomized, Double-Blind, Placebo-Controlled Trial of Polyphenon E in Prostate Cancer Patients before Prostatectomy: Evaluation of Potential Chemopreventive Activities +
Patients received no other therapy for their prostate cancer; no history of chemotherapy and/or radiation for any malignancy in the previous 5 years +
Niravath et al. (2019): Randomized controlled trial of high‐dose versus standard‐dose vitamin D3 for prevention of aromatase inhibitor‐induced arthralgia +
Aromatase inhibitor therapy +
O
Okabayashi et al. (2020): L-Carnitine Improves Postoperative Liver Function in Hepatectomized Patients +
Hepatectomy (n=30 bisegmentectomy or extended hepatectomy, n=69 segmentectomy, and n=109 subsegmentectomy) +
Olsen et al. (2001): The effect of aloe vera gel/mild soap versus mild soap alone in preventing skin reactions in patients undergoing radiation therapy +
Chemotherapy:
Aloe arm: Yes = 28%, No = 72%
Control arm: Yes = 26%, No = 74%
Cumulative dose was dichotomized into ≤2,700 cGy or >2,700 cGy. +
Ota et al. (2014): The effect of pyridoxine for prevention of hand-foot-syndrome in colorectal cancer patients with adjuvant chemotherapy using capecitabine: A randomized study +
Eight 3-week cycles of 2,500 mg/m2 of capecitabine per day in two divided doses for 14 days, followed by a 7-day rest period +
P
Pace et al. (2003): Neuroprotective Effect of Vitamin E Supplementation in Patient Treated With Cisplatin Chemotherapy +
Cisplatin-based chemotherapy;
Cisplatin was administered in combination regimens based on the specific tumor site as follows:
Lung and urethral cancer:cisplatin 75 mg/m² on day 1 and gemcitabine 1,000 mg/m² on day 1 and day 8 every 3 weeks; ovarian cancer: cisplatin 75 mg/m² and endoxan 600 mg/m² on day 1 every 3 weeks; head and neck cancer: cisplatin 100 mg/m² on day 1 and fluorouracil 1,000 mg/m² on day 1 to 4 every 3 to 4 weeks; ethmoidal cancer: cisplatin 25 mg/m² and etoposide 80 mg/m² on day 1 to 3 every 3 weeks; gastric cancer: PELF regimen (cisplatin 40 mg/m² and epirubicin 30 mg/m² on days 1 and 5 plus fluorouracil 300 mg/m² and folinic acid 100 mg/m² on days 1 to 4 every 3 weeks); testicular cancer: PEB regimen (cisplatin 20 mg/m² and etoposide 100 mg/m² on days 1 to 5 plus bleomycin 30 mg on days 2, 9, and 16 every 3 weeks) +
Cisplatin-based chemotherapy, cisplatin was administered in combination regimens on the basis of the specific tumor site +
Panahi et al. (2012): Effect of Ginger on Acute and Delayed Chemotherapy-Induced Nausea and Vomiting: A Pilot, Randomized, Open-Label Clinical Trial +
Patients experiencing their first trial of chemotherapy (Docetaxel, Epirubicin, Cyclophosphamid) +
Paur et al. (2017): Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA +
NA +
Portenoy et al. (2012): Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial +
NA +
Puataweepong et. al (2009): The efficacy of oral Aloe vera juice for radiation induced mucositis in head and neck cancer patients: a double-blind placebo-controlled study +
Previous surgery
Aloe arm: 4 (13%)
Placebo arm: 12 (38%)
Chemotherapy
Aloe arm: yes = 17 (57%); no = 13 (43%)
Placebo arm: yes = 18 (58%); no = 13 (42%) +
Concurrent chemotherapy with paclitaxel at a dose of 60 mg/m2i/v weekly +
R
Raei et al. (2013): Effect of herbal therapy to intensity chemotherapy-induced nausea and vomiting in cancer patients +
In: ≥2 cycles of cisplatin chemotherapy
Chemoregime:
50-100 mg Cisplatin +/- andere
Antiemetika: Granisetron 3 mg + Dexamethazon 8mg +
Rao et al. (2014): The Indian Spice Turmeric Delays and Mitigates Radiation-Induced Oral Mucositis in Patients Undergoing Treatment for Head and Neck Cancer: An Investigational Study +
Only radiation therapy, radiation therapy + chemotherapy or radiation therapy + chemotherapy + surgery +
Raoufinejad et al. (2019): Oral calcitriol in hematopoietic recovery and survival after autologous stem cell transplantation: a randomized clinical trial +
Autologous peripheral blood hematopoietic stem cell transplantation +