Property:Exclusion criteria
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Rastelli et al. (2011): Vitamin D and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial +
Had known metastatic disease to the bone, kidney stones, primary hyperparathyroidism, Paget’s disease of the bone, severe arthritis, rheumatoid arthritis, severe neuropathy or 25OHD C 30 ng/ml;
treatment on the trial was stopped if the patient developed hypercalciuria (C250 mg/g creatinine) or hypercalcemia (C10.3 mg/dl) +
Ribeiro et al. (2017): Effects of zinc supplementation on fatigue and quality of life in patients with colorectal cancer +
With liver, kidney, or chronic inflammatory autoimmune diseases; with active infectious diseases; who were undergoing therapy with immunosuppressants; who were on vitamin or mineral supplementation; who had been on chemo- or radiation therapy in the previous 12 months; and who had been diagnosed as cognitively impaired +
Ripamonti et al. (1998): A randomized, controlled clinical trial to evaluate the effects of zinc sulfate on cancer patients with taste alterations caused by head and neck irradiation +
Demolitive surgery of the tongue, palate, or oropharynx; the presence of oral lesions, such as stomatitis, ulcers, necrosis, or candidiasis; complete or full upper dentures; elimination of the olfactory component of taste after laryngectomy; concomitant administration of chemotherapy and or any other kind of drug affecting taste; lesions of cranial nerves V, VII, IX, or X; damage to the nervous system after surgery or cerebral lesions; metabolic alterations or disorders; endocrine or neurologic diseases known to influence taste and/or smell sensitivity; local disease in the nose or ears; and lack of cooperation on the part of patients +
Rostock et al. (2013): Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: A Four-Arm Randomized Trial on the Effectiveness of Electroacupuncture +
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Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients +
Patients on coumadin or heparin for therapeutic anticoagulation, patients with a bleeding disorder, patients who hadn't had platelet count >100,000/μl before the baseline cycle +
Ryan et al. (2013): Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients +
Patients who: had bilateral breast cancer; previous radiation to the chest or breast area; diagnosis of inflammatory breast cancer; breast reconstruction and/or expanders prior to RT; were taking anti-coagulant therapy (warfarin, coumadin or heparin) or antiepidermal growth factor receptor (EGFR) therapy or were receiving partial breast irradiations +
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Sahebjamee et al. (2015): Comparative Efficacy of Aloe vera and Benzydamine Mouthwashes on Radiation-induced Oral Mucositis: A Triple-blind, Randomised, Controlled Clinical Trial +
Radiotherapy in the past year; food allergy; hypersensitivity to benzydamine, NSAIDs, or aloe; existing lesions in the oral cavity +
Sahebnasagh et al. (2017): Successful Treatment of Acute Radiation Proctitis with Aloe Vera: A Preliminary Randomized Controlled Clinical Trial +
Active infection; other causes of haematochezia including bowel cancer; IBD; haemorrhoids; anal incontinence; anorectal fistula; anorectal stenosis; previous rectal surgery; pregnant or breastfeeding women; women of childbearing age without appropriate contraception; allergy to components of the ointments tested; use of antibiotics or steroids +
Salehi et al. (2015): Effect of Vitamin E on Oxaliplatin-induced Peripheral neuropathy Prevention: A Randomized Controlled Trial +
Previous history of peripheral neuropathy or symptomatic peripheral neuropathy at entry into the study, received other chemotherapy regimens, currently receiving anticoagulants, platelet aggregation inhibitors, opioids, anticonvulsants, tricyclic antidepressants, and previous history of hemorrhagic stroke +
Salihah et al. (2016): The effectiveness of inhaled ginger essential oil in improving dietary intake in breast-cancer patients experiencing chemotherapy-induced nausea and vomiting +
Women with other malignancies, allergies to ginger, perfumes or cosmetics or who were undergoing concurrent radiotherapy +
Sanaati et al. (2016): Effect of Ginger and Chamomile on Nausea and Vomiting Caused by Chemotherapy in Iranian Women with Breast Cancer +
Patients with multiple-day chemotherapy; receiving concurrent radiotherapy with high risk of causing emesis (i.e., total body, hemi body, upper abdomen, and craniospinal radiation); taking therapeutic doses of warfarin, aspirin, or heparin; had a history of bleeding disorder(s) like severe thrombocytopenia; had an allergy to ginger or chamomile or had taken it in the last week; had gastrointestinal disorders and cancers; and had other emesis-inducing diseases, such as hypertension, liver, and renal failure.
Further exclusion of patients who met the following criteria: forgotten to take capsules ≥3 consecutive times; used other antiemetic drugs or therapeutic methods except the routine antiemetic; had severe gastrointestinal problems during the study; and refusal to continue participating in trial. +
Sangthawan et al. (2013): A randomized double-blind, placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patients +
Previously diagnosed with cancer, had other concomitant cancers, distant metastases or recurrent cancer, had undergone prior radiation therapy or chemotherapy, or had received drug containing zinc +
Sangthawan et al. (2015): Effects of zinc sulfate supplementation on cell-mediated immune response in head and neck cancer patients treated with radiation therapy +
A previous diagnosis of cancer, a concomitant cancer, distant metastases or recurrent cancer, prior radiation therapy or chemotherapy, pregnancy, an autoimmune disease, or drugs received that contained zinc +
Scher et al. (2011): Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer +
Prior cytotoxic chemotherapy (except estramustine monotherapy), bone-seeking radioisotope therapy, prior untreated CNS involvement, or malignancy other than prostate cancer (except adequately treated basal or squamous cell skin cancer or any other cancer from which the individual had been disease free for > 5 years), history of hypercalcemia or vitamin D toxicity, active uncontrolled infection, symptomatic peripheral neuropathy of grade > 2, or hypersensitivity to any treatment component;
use of calcium supplements higher than 500 mg and pharmacologic doses of vitamin D or its derivatives (> 400 U or 10 μg) +
Shamsaei et al. (2017): The Vitamin E Preventive Effect on Taxol-Induced Neuropathy Among Patients With Breast Cancer: A Randomized Clinical Trial +
History of peripheral neuropathy and systemic diseases such as diabetes mellitus, systemic lupus erythematosus, HIV, and alcohol problems, as well as those with a history of chemotherapy treatment +
Shapiro et al. (2016): Randomized, blinded trial of vitamin D3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS) +
Received previous aromatase inhibitor treatment, had a history of rheumatoid arthritis, hypercalcemia or were taking excluded medications, unwilling to discontinue other oral supplements containing D3 and/or calcium;
patients with osteoporosis in some cases +
Sharp et al. (2009): A randomised, controlled trial of the psychological effects of reflexology in early breast cancer +
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Sharp et al. (2010): A randomised, controlled trial of the psychological effects of reflexology in early breast cancer +
History of cancer (excluding basal cell carcinoma), participating in another clinical trial and clinically significant cognitive impairment or dementia. +
Shokri et al. (2017): Comparison of the Complications of Platinum-Based Adjuvant Chemotherapy With and Without Ginger in a Pilot Study on Ovarian Cancer Patients +
The exclusion criteria included allergy to ginger, history of chemotherapy, history of other malignancy in women, reception of vitamin E and omega-3 before or concurrent with chemotherapy, chemotherapy intolerance and patients with stage 4 ovarian cancer. +
Shooriabi et al. (2016): The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: A double-blind controlled study +
Being pregnant, diabetes, asthma, Sjogren's syndrome, lack of ability to feed by mouth, using anti-depressant medications, a history of allergy to ginger or corn starch and people who have had recurrence of cancer and residence outside the city of Ahvaz and the lack of consent of the participation in the study. +