Property:Drop-out reasons
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Johnson et al. (2010): Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain +
Adverse event (n=3); consent withdrawal (n=2); other (n=3) +
Jyothirmayi et al. (1996): Efficacy of Vitamin A in the Prevention of Locoregional Recurrence and Second Primaries in Head and Neck Cancer +
NI +
Jyothirmayi et al. (1996): Efficacy of Vitamin A in the Prevention of Locoregional Recurrence and Second Primaries in Head and Neck Cancer +
NI +
K
Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597 +
Ineligible (n = 6);
No therapy (n = 2)
Discontinued treatment:
Completed (n = 134);
Progression (n = 52);
Toxicity (n = 8);
Death (n = 12);
Withdrawal (n = 67);
Nonprotocol treatment (n = 3);
Complicating disease (n = 17);
Other (n = 105) +
Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597 +
Ineligible (n = 10);
No therapy (n = 12)
Discontinued treatment:
Completed (n = 238);
Progression (n = 117);
Toxicity (n = 20);
Death (n = 18);
Withdrawal (n = 157);
Nonprotocol treatment (n = 1);
Complicating disease (n = 30);
Maximum dose (n = 2);
Other (n = 212) +
Kasseroller et al. (2003): Efficacy and tolerability of proteolytic enzymes as an anti-inflammatory agent in lymphoedema after axillary dissection due to mammary cancer +
Gastrointestonal side effects +
Kasseroller et al. (2003): Efficacy and tolerability of proteolytic enzymes as an anti-inflammatory agent in lymphoedema after axillary dissection due to mammary cancer +
Side effects +
Keshavarzi et al. (2019): The effect of vitamin D and E vaginal suppositories on tamoxifen-induced vaginal atrophy in women with breast cancer +
NA +
Keshavarzi et al. (2019): The effect of vitamin D and E vaginal suppositories on tamoxifen-induced vaginal atrophy in women with breast cancer +
NA +
Keshavarzi et al. (2019): The effect of vitamin D and E vaginal suppositories on tamoxifen-induced vaginal atrophy in women with breast cancer +
NA +
Kessels et al. (2017): Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma A Randomized Clinical Trial +
No reasons reported +
Kessels et al. (2017): Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma A Randomized Clinical Trial +
No reasons reported +
Khan et al. (2017): Randomized trial of vitamin D3 to prevent worsening of musculoskeletal symptoms in women with breast cancer receiving adjuvant letrozole. The VITAL trial +
n=2 protocol violations, n=7 withdrew for reasons other than study agent related adverse events +
Khan et al. (2017): Randomized trial of vitamin D3 to prevent worsening of musculoskeletal symptoms in women with breast cancer receiving adjuvant letrozole. The VITAL trial +
Withdrew for reasons other than study agent related adverse events +
Khodabakhshi et al. (2019): Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study +
Nausea and hypoglysemia; weakness and hunger; refusal to participate; unable to stick to diet; lack of energy and oiliness of the diet +
Khodabakhshi et al. (2019): Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study +
Frequent blood sampling; surgery; diabetes +
Kirste et al. (2011): Boswellia serrata Acts on Cerebral Edema in Patients Irradiated for Brain Tumors. A Prospective, Randomized, Placebo-Controlled, Double-Blind Pilot Trial +
Could not swallow capsules n = 1
Refused to swallow capsules n = 1 +
Kirste et al. (2011): Boswellia serrata Acts on Cerebral Edema in Patients Irradiated for Brain Tumors. A Prospective, Randomized, Placebo-Controlled, Double-Blind Pilot Trial +
Refused to swallow capsules n = 1
Epileptic seizure grade 4, discontinued therapy n = 1 +
Konmun et al. (2017): A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy +
Before treatment:
- consent withdrawn (n=2)
- referred for treatment at another hospital (n=1)
- inability to swallow a capsule (n=1)
After treatment (but excluded from analysis):
- protocol violation (n=1)
- consent withdrawn (n=2) +
Konmun et al. (2017): A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy +
Before treatment:
- consent withdrawn (n=1)
- referred for treatment at another hospital (n=1)
After treatment (but excluded from analysis):
- consent withdrawn (n=5) +