Property:Exclusion criteria
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Patients with an existing pregnancy; younger than 18 years or older than 80 years; patients with a known intolerance to the enzyme preparation +
Vitale et al. (2020): ZeOxaNMulti Trial: A Randomized, Double-Blinded, Placebo-Controlled Trial of Oral PMA-Zeolite to Prevent Chemotherapy-Induced Side Effects, in Particular, Peripheral Neuropathy +
Chemotherapy treatment with neurotoxic drugs (cisplatin, carboplatin, oxaliplatin, vincristine, vinblastine, paclitaxel, or docetaxel) in the 6 months prior to the start of oxaliplatin-chemotherapy, pregnancy, or breastfeeding +
W
Walsh et al. (2010): Use of alpha,25-dihydroxyvitamin D3 treatment to stimulate immune infiltration into head and neck squamous cell carcinoma +
Had received immunotherapy or radiation treatment in the previous 3 weeks or concurrent malignancies +
Watanabe et al. (2010): Polaprezinc prevents oral mucositis associated with radiochemotherapy in patients with head and neck cancer +
NI +
Williams et al. (1996): Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity +
? +
Wrbka et al. (1987): Unterstützung der Chemotherapie inoperabler Karzinome durch proteolytische Fermente +
NI +
Wyatt et al. (2012): Health-Related Quality-of-Life Outcomes: A Reflexology Trial With Patients With Advanced-Stage Breast Cancer +
Receiving hospice care at intake, residing in a nursing home or similar care facility, being bedridden, regularly using CAM similar to those used in the protocol (e.g., reflexology, foot massage, pedicure with massage), and participating in an experimental chemotherapy protocol. +
Wyatt et al. (2017): A Randomized Clinical Trial of Caregiver-Delivered Reflexology for Symptom Management During Breast Cancer Treatment +
Patient exclusion criteria were 1) diagnosis of major mental illness in the medical record and verified by the recruiter, 2) residing in a nursing home, 3) bedridden, 4) currently receiving reg- ular reflexology, or 5) diagnoses of symptoms of deep vein thrombosis or painful foot neuropathy.
Friend/family caregiver: Exclusion criterion was unwilling to perform a return demonstration of the protocol according to training procedures. +
Y
Yap et al. (2017): Predictors of hand-foot syndrome and pyridoxine for prevention of capecitabine-induced hand-foot syndrome: a randomized clinical trial +
NI +
Patients were excluded if they were receiving multiple-day chemotherapy; receiving concurrent radiotherapy with high risk of causing emesis (ie, total body, hemi body, upper abdomen, and craniospinal radiation); taking therapeutic doses of warfarin, aspirin, or heparin; had a history of bleeding disorder(s) like severe thrombocytopenia; had an allergy to ginger or had taken it in the last week; had gastrointestinal disorders and cancers; and had other emesis-inducing diseases, such as hypertension, liver, and renal failure.
Patients who forgot to take capsules ≥ 3 consecutive times; used other antiemetic drugs or therapeutic methods except the routine antiemetic; had severe gastrointestinal problems during the study; and refusal to continue participating in trial. +
Z
Zalat et al. (2020): Evaluation of the cardioprotective effects of l-carnitine and silymarin in cancer patients receiving anthracycline-containing chemotherapy +
Patients with a history of heart failure, arrhythmia, history of cardiac catheterizations or, history of angina, uncontrolled hypertension and uncontrolled diabetes, patients with impaired liver function tests, previous anthracycline-containing regimens and any cardiotoxic chemotherapy regimens, previous history of chest wall irradiation. Brain metastasis, pregnant patients, and patients who refused informed consent, patients who could not be sampled serially, or had bypass surgery, which precluded sampling throughout their hospital stay +
Zick et al. (2008): Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting +
If they were:
- Receiving multiple-day chemotherapy;
- Receiving concurrent radiotherapy that was classified as high or intermediate risk of causing emesis (i.e., total body irradiation, hemi-body, upper abdomen, abdominalpelvic mantle, cranium, or craniospinal irradiation);
- taking therapeutic doses of coumadin (individuals on low-dose coumadin to maintain peripheral or central venous catheters were allowed), aspirin (individuals taking low- dose 81 mg aspirin were allowed), or heparin;
- Had a history of a bleeding disorder(s) and those experiencing clinically significant thrombocytopenia;
- Had an allergy to ginger or had taken ginger in the last week;
- Nursing mothers, pregnant women, or planning a pregnancy during the study period. +
Ö
Özdelikara et al. (2017): The Effect of Reflexology on Chemotherapy-induced Nausea, Vomiting, and Fatigue in Breast Cancer Patients +
Radiotherapy +
Özdelikara et al. (2017): The effect of reflexology on the quality of life with breast cancer patients +
Hemorrhage, epilepsy or fever, paraplegia or thrombosis, gall-kidney stone, leg varicosis or foot disease (open wound or fracture on foot), diagnosis of psychiatric disorder or dementia, having accepted to participate in the study +