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Property:Results after intervention

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There was no significant difference between the two treatment arms in terms of cumulative probability, prevalence, or duration of erythema. For subjects who did not have chemotherapy, those in the placebo arm had a significantly greater incidence of grade 2 or more erythema than those in the aloe vera arm (71% vs. 51%) (p = 0.02).  +
The cumulative probability for any dry desquamation (>1%) was greater in the aloe vera arm compared with the placebo arm (70% vs. 41%) (p<0.001) There was no difference in the duration of reaction between the two treatment arms. There was no significant difference between the two treatment arms in terms of cumulative probability, prevalence, or duration of moist desquamation.  +
For the subjects the cumulative probability of grade 2 or more pain was greater in the aloe vera arm than in the placebo arm (26% vs. 17%) (p = 0.03). For subjects who had drainage, those in the aloe vera arm had a significantly greater incidence of grade 2 or more pain compared with those in the placebo arm (40% vs. 20%) (p = 0.01). For subjects who received chemotherapy, there was no difference in pain levels between the two treatment arms. For subjects, who did not have chemotherapy, those in the aloe vera arm had a significantly greater incidence of grade 2 or more pain compared with those in the placebo arm (26% vs. 12%) (p = 0.02).  +
The cumulative probability for itching toxicity (grades 1 or more, grades 2 or more, grades 3 or more) was greater in the aloe vera arm than in the placebo arm, but the difference was not significant. There was no significant difference between the treatment arms for grade 2 or more itching according to whether or not a subject had undergone chemotherapy. Drainage: The proportion of subjects who had lymphocele drainage was similar in both arms. Within the aloe vera arm, subjects who had lymphocele drainage experienced a significantly greater incidence of grade 2 or more itching compared with subjects who did not have lymphocele drainage (46% vs. 23%) (p = 0.01).There was no significant difference within the placebo arm for drainage versus no drainage.  +
Three month after radiotherapy mean difference intervention vs. placebo arm (controlled for baseline value) (95% CI): * Urinary symptoms: -14.1 (-24.7, -3.4); p = 0.011; intervention significantly fewer symptoms than placebo arm * Bladder symptoms: 5.4 (-4.5, 15.4); p = 0.275 * Treatment-related symptoms: 7.9 (-3.1, 18.9); p = 0.155 * Sexual activity: -3.5 (-19.0, 12.0); p = 0.652  +
PSA level (ng/ml) within 3 months: * Mean change (SD): Intervention arm 0.12 ( 0.16), placebo arm: 0.13 (0.06); p = 0.78 * No information on PFS within one year  +
Decrease in serum PSA levels higher in the green tea arm compared to the water arm (p=0.04) PSA mean (SD) per arm Green tea arm (N=30): baseline= 9.6(5.2); after 33 days= 8.4(4.3) Water arm (N=30): baseline= 9.9(8.5); after 29 dayse= 10.0(9.0) No significant difference in changes between black tea arm and water arm (p>0.05)  +
Detection of tea polyphenols in prostate tissue in 32 of 34 men in the green tea arm , but not in the other arms. Detection of EGC, EC and methyl-EGC in early morning urine throughout the study in the green tea arm and at significantly lower concentrations in the black tea arm (p<0.01); no polyphenols in the water arm.  +