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Property:Dosage and regime

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A
1g; 2x daily Duration: day -2 chemotherapy until 20 days after the end of the chemotherapy cycle for 4 chemotherapy cycles  +
1g; 2x daily Duration: day -2 chemotherapy until 20 days after the end of the chemotherapy cycle for 4 chemotherapy cycles  +
oral, 200mg, 2x daily Duration: day -2 chemotherapy until 20 days after the end of the chemotherapy cycle for 4 chemotherapy cycles  +
B
In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported. '''OLD''' (n=77) - 1 placebo daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days '''NEW''' (n=190) - 2 placebos daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy  +
In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported. '''OLD''' (n=79) - 30mg Betacarotin + 400 IU Vitamin E daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days '''NEW''' (n=194) - 400 IU Vitamin E daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy  +
In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported. '''OLD''' (n=77) - 1 placebo daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days '''NEW''' (n=190) - 2 placebos daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy  +
In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported. '''OLD''' (n=79) - 30mg Betacarotin + 400 IU Vitamin E daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days '''NEW''' (n=194) - 400 IU Vitamin E daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy  +
In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported. '''OLD''' (n=77) - 1 placebo daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days '''NEW''' (n=190) - 2 placebos daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy  +
In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported. '''OLD''' (n=79) - 30mg Betacarotin + 400 IU Vitamin E daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days '''NEW''' (n=194) - 400 IU Vitamin E daily, start with first day of radiotherapy - Duration: up to 3 years after radiotherapy  +
Daily dose 4 Placebo capsule, i.e. 2 capsules in the morning and 2 capsules in the late afternoon, starting the day after chemotherapy for 42-56 days (depending on duration of chemotherapy)  +
Daily dose 4x40mg ginger capsule (“Ginger CO2 supercritical extract”), i.e. 2 capsules in the morning and 2 capsules in the late afternoon, starting the day after chemotherapy for 42-56 days (depending on duration of chemotherapy)  +
2 placebo capsules/ day (composed of wheat starch with no added zinc) + vaccination with 1 dose of 0.5 mL of 23-valent pneumococcal polysaccharide vaccine (Pneumovax 23 , Merck, Whitehouse Station, NJ), containing 25 mg of capsular polysaccharide antigen from 23 different pneumococcal serotypes (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F); 2 days after zinc supplementation started  +
2 zinc sulfate capsules/ day (each containing 35 mg of elemental zinc); first capsule 1h after breakfast and the other 1h after dinner + vaccination with 1 dose of 0.5 mL of 23-valent pneumococcal polysaccharide vaccine (Pneumovax 23 , Merck, Whitehouse Station, NJ), containing 25 mg of capsular polysaccharide antigen from 23 different pneumococcal serotypes (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F); 2 days after zinc supplementation started  +