Property:Results during intervention
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Hershman et al. (2018): Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L Carnitine +
Baseline to week 104: Intervention arm sign. Reduction in NTX (more severe neuropathy) compared to placebo arm (mean difference -1.39 points, 95% CI = -2.48, -0.30; p=0.01); particularly strong at week 24 (end of intervention) (-1.68, 95% CI = -3.02, -0.33)
Further results see study [[Hershman et al. (2013): Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy]] +
Hodgson et al. (2012): Reflexology versus Swedish Massage to Reduce Physiologic Stress and Pain and Improve Mood in Nursing Home Residents with Cancer: A Pilot Trial. +
Reflextherapy: The values after treatment are significantly higher than before treatment: mean diff.= 0.67; p<0.05; effect size = 0.73.
Massage: The values after the treatment are significantly higher than before the treatment: mean diff.= 0.36; p<0.05; effect size = 0.30;
The difference between the groups is not significant +
Hodgson et al. (2012): Reflexology versus Swedish Massage to Reduce Physiologic Stress and Pain and Improve Mood in Nursing Home Residents with Cancer: A Pilot Trial. +
Reflextherapy: The values after the treatment are significantly lower than before the treatment Mean diff.= -0.29; p<0.05; effect size = -0.35.
Massage: The values after the treatment are significantly lower than before the treatment Mean diff.= -0.71; p<0.05; effect size ES= -0.77;
The difference between the arms is not significant: p=0.22. +
Hodgson et al. (2012): Reflexology versus Swedish Massage to Reduce Physiologic Stress and Pain and Improve Mood in Nursing Home Residents with Cancer: A Pilot Trial. +
Reflextherapy: The values after the treatment are significantly lower than before the treatment: mean diff.= -0.35; p<0.05; effect size = -0.42.
Massage: The values after the treatment are significantly lower than before the treatment: mean diff.= -0.23; p<0.05; effect size ES= -0.30;
The difference between the arms is not significant: p=0.16. +
Hoopfer et al. (2015): Three-arm randomized phase III trial: Quality aloe and placebo cream versus powder as skin treatment during breast cancer radiation therapy +
The severity followed the same sequence trajectory in all 3 arms with a peak effect commonly occurring within the first week after end of radiation, although for 10 patients, the peak reaction occurred at 2 weeks after radiation (7 in the aloe cream, 1 in the placebo cream, and 2 in the powder arm)
Erythema as the maximum reaction (CSSP score 1-4) occurred in 16.5% of the powder, 8.6% of the aloe cream, and 6.6% of the placebo cream arms.
Dry desquamation as a maximum reaction (CSSP score 5-6) occurred in 35.4% of the powder, 28.4% of the aloe cream, and 29% of the placebo cream arms.
Moist desquamation in < 50% of the field as the maximum reaction (CSSP score 7-8) occurred in 44.3% of the powder, 49.4% of the aloe cream, and 56.6% of the placebo cream arms.
Moist desquamation in > 50% of the field as a maximum reaction (CSSP score 9-10) occurred in 3.8% of the powder, 13.6% of the aloe cream, and 7.9% of the placebo cream arms. +
Hoopfer et al. (2015): Three-arm randomized phase III trial: Quality aloe and placebo cream versus powder as skin treatment during breast cancer radiation therapy +
NI +
Hoopfer et al. (2015): Three-arm randomized phase III trial: Quality aloe and placebo cream versus powder as skin treatment during breast cancer radiation therapy +
NI +
Howells et al. (2011): Phase I randomised double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases - safety, pharmacokinetics and pharmacodynamics +
NA +
Howells et al. (2011): Phase I randomised double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases - safety, pharmacokinetics and pharmacodynamics +
NA +
I
Inglis et al. (2020): Effects of High-Dose Vitamin D Supplementation on Phase Angle and Physical Function in Patients with Prostate Cancer on ADT +
No significant differences between arms at any time point +
Inglis et al. (2020): Effects of High-Dose Vitamin D Supplementation on Phase Angle and Physical Function in Patients with Prostate Cancer on ADT +
Phase angle: significantly wider phase angle values in intervention arm at week 12 (p=0.014;95% CI -0.824, -0.098) and at week 24 (p=0.018; 95% CI -0.922, -0.090)
Lean mass: significantly higher in intervention arm at week 12 (p=0.036; 95% C.I. 0.229, 6.556) but no significant differences between arms at any other time point +
Iovino et al. (2018): High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ naive lymphocytes and prevents TTV reactivation +
No statistical differences in baseline zinc serum levels;
at the end of the supplementation period, although zinc serum levels were higher in the zinc group, the difference between the groups was not significant +
J
Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study +
Difference in baseline Quality of Life for the physical function (p = 0.028), higher in the intervention arm and diarrhea, more severe in the control arm (p = 0.093);
no statistically significant difference was observed between intervention and control arms at 6 months,
there was no significant difference in overall Quality of Life between the normalized and deficient populations at 6 months +
Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study +
After 6 months, significantly more patients in the intervention arm had a normalized serum vitamin D level compared with the control arm patients (30% versus 12.6%; p = 0.003),
the median 6 month-vitamin D level was 24.2 ng/ml (8.1–39.2) and 28.1 ng/ml (7.3–51.8) respectively in the control and intervention arms (p < 0.001);
Percentage of correction was significantly higher in the intervention arm for patients included during fall (28% vs. 3%; p = 0.006), there was a trend in favor of intervention arm for patients included during winter (52% vs. 28%; p = 0.083), while there was no significant difference for patients included in spring and summer; +
Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial +
NA +
Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial +
NA +
Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial +
NA +
Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial +
No difference between arms (p=0.32, p=0.87) +