Property:Side Effects / Interactions
This is a property of type Text.
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Nasser et al. (2017): Vitamin D ointment for prevention of radiation dermatitis in breast cancer patients +
Vitamin D was well tolerated by patients with no localized or systemic allergic reactions. +
Nasser et al. (2017): Vitamin D ointment for prevention of radiation dermatitis in breast cancer patients +
Vitamin D was well tolerated by patients with no localized or systemic allergic reactions. +
Newling et al. (1995): Tryptophan metabolites, pyridoxine (vitamin B6) and their influence on the recurrence rate of superficial bladder cancer. Results of a prospective, randomised phase III study performed by the EORTC GU Group +
NI +
Newling et al. (1995): Tryptophan metabolites, pyridoxine (vitamin B6) and their influence on the recurrence rate of superficial bladder cancer. Results of a prospective, randomised phase III study performed by the EORTC GU Group +
NI +
Ng et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial +
Most common adverse events: neutropenia (21 patients (31%)) and hypertension (11 patients (16%)), diarrhea (8 patient (12%)) +
Ng et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial +
Most common adverse events: neutropenia (24 patients (35%)) and hypertension (9 patients (13%)), diarrhea (1 patient (1%)),
the only adverse events that were reported as possibly related to vitamin D3 were hyperphosphatemia (1 patient in intervention arm) and kidney stones (1 patient in the placebo arm) +
Nguyen et al. (2012): Randomized, Double-Blind, Placebo-Controlled Trial of Polyphenon E in Prostate Cancer Patients before Prostatectomy: Evaluation of Potential Chemopreventive Activities +
The NCI Common Terminology Criteria for Adverse Events (CTCAE) version 3.0 and diary were used for adverse event description and grading; side effects were all grade I or II; Summary of adverse events occurring in greater than 4% of subjects treated with polyphenon E or placebo, regardless of attribution
Polyphenon E (N = 25), n (%)
Nausea: 4 (16)
Diarrhea: 2 (8)
Headache: 1 (4) +
Nguyen et al. (2012): Randomized, Double-Blind, Placebo-Controlled Trial of Polyphenon E in Prostate Cancer Patients before Prostatectomy: Evaluation of Potential Chemopreventive Activities +
The NCI Common Terminology Criteria for Adverse Events (CTCAE) version 3.0 and participant diary were used to for adverse event description and grading; side effects were all grade I or II; summary of adverse events occurring in greater than 4% of subjects treated with polyphenon E or placebo, regardless of attribution
Placebo (N = 25), n (%)
Nausea: 4 (16)
Diarrhea: 5 (20)
Headache: 2 (8)
Fever: 3 (12)
Body ache: 2 (8)
Muscle ache: 2 (8) +
Niravath et al. (2019): Randomized controlled trial of high‐dose versus standard‐dose vitamin D3 for prevention of aromatase inhibitor‐induced arthralgia +
No grade 4 or grade 5 adverse events, n=1 renal stones, 4 grade 3 events (deemed to be unrelated to the study drugs) +
Niravath et al. (2019): Randomized controlled trial of high‐dose versus standard‐dose vitamin D3 for prevention of aromatase inhibitor‐induced arthralgia +
No grade 4 or grade 5 adverse events, n=1 hypercalcemia, 8 grade 3 events (deemed to be unrelated to the study drugs) +
O
Okabayashi et al. (2020): L-Carnitine Improves Postoperative Liver Function in Hepatectomized Patients +
Authors: “L-carnitine was well tolerated by all patients.”
No differences in mortality as of March 2018. +
Okabayashi et al. (2020): L-Carnitine Improves Postoperative Liver Function in Hepatectomized Patients +
Authors: “L-carnitine was well tolerated by all patients.”
No differences in mortality as of March 2018. +
Olsen et al. (2001): The effect of aloe vera gel/mild soap versus mild soap alone in preventing skin reactions in patients undergoing radiation therapy +
Not reported, although no allergic skin reactions to aloe have been documented. +
Olsen et al. (2001): The effect of aloe vera gel/mild soap versus mild soap alone in preventing skin reactions in patients undergoing radiation therapy +
NA +
Ota et al. (2014): The effect of pyridoxine for prevention of hand-foot-syndrome in colorectal cancer patients with adjuvant chemotherapy using capecitabine: A randomized study +
NI +
Ota et al. (2014): The effect of pyridoxine for prevention of hand-foot-syndrome in colorectal cancer patients with adjuvant chemotherapy using capecitabine: A randomized study +
NI +
P
Pace et al. (2003): Neuroprotective Effect of Vitamin E Supplementation in Patient Treated With Cisplatin Chemotherapy +
NA +
Pace et al. (2003): Neuroprotective Effect of Vitamin E Supplementation in Patient Treated With Cisplatin Chemotherapy +
According to information no side effects. +
According to information no side effects +
According to information no side effects +