Property:Side Effects / Interactions
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B
Braik et al. (2014): Randomized trial of vitamin B6 for preventing hand-foot syndrome from capecitabine chemotherapy +
NI +
Brown et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Body Composition among Patients with Advanced or Metastatic Colorectal Cancer: A Randomized Trial +
NI +
Brown et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Body Composition among Patients with Advanced or Metastatic Colorectal Cancer: A Randomized Trial +
NI +
Büntzel et al. (2010): Limited effects of selenium in the prevention of radiation-associated toxicities - results of a randomized study in head neck cancer patients +
NI +
Büntzel et al. (2010): Limited effects of selenium in the prevention of radiation-associated toxicities - results of a randomized study in head neck cancer patients +
NA +
Büntzel et al. (2010): Selenium Substitution During Radiotherapy of Solid Tumours - Laboratory Data from Two Observation Studies in Gynaecological and Head and Neck Cancer Patients +
NA +
Büntzel et al. (2010): Selenium Substitution During Radiotherapy of Solid Tumours - Laboratory Data from Two Observation Studies in Gynaecological and Head and Neck Cancer Patients +
NI +
C
Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy +
Insomnia: Guarana: n = 22, placebo: n = 31,
Palpitation: Guarana: n = 10, placebo: n = 12,
Nausea: Guarana: n = 25, placebo: n = 35,
Anxiety: Guarana: n = 17, placebo: n = 25,
Dermatologic: Guarana: n = 1, placebo: n = 3
Total Guarana n=30, Placebo n=45, no statistical comparison conducted +
Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy +
Insomnia: Guarana: n = 22, placebo: n = 31,
Palpitation: Guarana: n = 10, placebo: n = 12,
Nausea: Guarana: n = 25, placebo: n = 35,
Anxiety: Guarana: n = 17, placebo: n = 25,
Dermatologic: Guarana: n = 1, placebo: n = 3 +
Cavallini et al. (2005): Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy +
Headache (25%), flushing (21.8%), drowsiness (9.4%), nausea (6.2%), rhinitis (6.2%), euphoria (6.2%), according to authors caused by sildenafil (no difference in side effects between both sildenafil arms) +
Cavallini et al. (2005): Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy +
Abdominal pain (3.4%) +
Cavallini et al. (2005): Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy +
Headache (28.1%), flushing (22.8%), drowsiness (8.5%), rhinitis (8.5%), nausea (5.7%), according to authors caused by sildenafil (no difference in side effects between sildenafil arms) +
Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer +
No side effects / interactions +
Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer +
Digestive disorder (n=2), migraine (n=1) +
Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer +
No side effects / interactions reported +
Chung et al. (2016): Randomized Trial of Vitamin C/E Complex for Prevention of Radiation- Induced Xerostomia in Patients with Head and Neck Cancer +
No significant adverse events or side effects related to study medication noticed/reported throughout the trial +
Chung et al. (2016): Randomized Trial of Vitamin C/E Complex for Prevention of Radiation- Induced Xerostomia in Patients with Head and Neck Cancer +
No significant adverse events or side effects related to study medication noticed/reported throughout the trial +
Cohen et al. (2018): Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial +
NI
Weight loss unclear +
Cohen et al. (2018): Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial +
NI
Weight loss unclear +
Crew et al. (2012): Phase IB Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Women with Hormone Receptor–Negative Breast Cancer +
Recording with CTCAE
Side effects in all Poly E arms: number of patients in n (%)
Nausea: 8 (27)
Diarrhoea: 3 (10)
Constipation: 3 (10)
Indigestion: 10 (33)
Abdominal pain: 1 (3)
Flatulence: 1 (3)
Gastrointestinal haemorrhage: 1 (3)
Weight gain: 1 (3)
Palpitations: 1 (3)
Elevated transaminases: 3 (10)
Elevated alkaline phosphatase: 2 (7)
Elevated lipase: 2 (7)
Elevated uric acid: 1 (3)
Proteinuria: 3 (10)
Anaemia: 2 (7)
Headache: 2 (7)
Insomnia: 4 (13)
Irregular menstruation: 1 (3)
Hot flushes: 1 (3) +