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Property:Side Effects / Interactions

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Insomnia: Guarana: n = 22, placebo: n = 31, Palpitation: Guarana: n = 10, placebo: n = 12, Nausea: Guarana: n = 25, placebo: n = 35, Anxiety: Guarana: n = 17, placebo: n = 25, Dermatologic: Guarana: n = 1, placebo: n = 3 Total Guarana n=30, Placebo n=45, no statistical comparison conducted  +
Insomnia: Guarana: n = 22, placebo: n = 31, Palpitation: Guarana: n = 10, placebo: n = 12, Nausea: Guarana: n = 25, placebo: n = 35, Anxiety: Guarana: n = 17, placebo: n = 25, Dermatologic: Guarana: n = 1, placebo: n = 3  +
Headache (25%), flushing (21.8%), drowsiness (9.4%), nausea (6.2%), rhinitis (6.2%), euphoria (6.2%), according to authors caused by sildenafil (no difference in side effects between both sildenafil arms)  +
Headache (28.1%), flushing (22.8%), drowsiness (8.5%), rhinitis (8.5%), nausea (5.7%), according to authors caused by sildenafil (no difference in side effects between sildenafil arms)  +
No significant adverse events or side effects related to study medication noticed/reported throughout the trial  +
No significant adverse events or side effects related to study medication noticed/reported throughout the trial  +
Recording with CTCAE Side effects in all Poly E arms: number of patients in n (%) Nausea: 8 (27) Diarrhoea: 3 (10) Constipation: 3 (10) Indigestion: 10 (33) Abdominal pain: 1 (3) Flatulence: 1 (3) Gastrointestinal haemorrhage: 1 (3) Weight gain: 1 (3) Palpitations: 1 (3) Elevated transaminases: 3 (10) Elevated alkaline phosphatase: 2 (7) Elevated lipase: 2 (7) Elevated uric acid: 1 (3) Proteinuria: 3 (10) Anaemia: 2 (7) Headache: 2 (7) Insomnia: 4 (13) Irregular menstruation: 1 (3) Hot flushes: 1 (3)  +