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List of results

Hejazi et al. (2013): A pilot clinical trial of radioprotective effects of curcumin supplementation in patients with prostate cancer + (According to information no side effects)
Hejazi et al. (2016): Effect of Curcumin Supplementation During Radiotherapy on Oxidative Status of Patients with Prostate Cancer: A Double Blinded, Randomized, Placebo-Controlled Study + (According to information no side effects)
Pace et al. (2010): Vitamin E neuroprotection for cisplatin neuropathy + (According to information no side effects)
Pace et al. (2010): Vitamin E neuroprotection for cisplatin neuropathy + (According to information no side effects)
Ryan et al. (2013): Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients + (According to information no side effects.)
Ryan et al. (2013): Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients + (According to information no side effects.)
Pace et al. (2003): Neuroprotective Effect of Vitamin E Supplementation in Patient Treated With Cisplatin Chemotherapy + (According to information no side effects.)
Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy + (According to reporting, no side effects/ interactions.)
Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy + (According to reporting, no side effects/ interactions.)
Stauder et al. (1991): Strahlentherapeutische Nebenwirkungen bei Abdominalkrebspatienten und deren Reduktion durch hydrolytische Enzyme + (According to the authors the tablets were mostly well or very well tolerated.)
Henning et al. (2015): Randomized Clinical Trial of Brewed Green and Black Tea in Men With Prostate Cancer Prior to Prostatectomy + (According to the authors, there were no serious side effects associated with the intervention; no information on the recording of side effects)
Henning et al. (2015): Randomized Clinical Trial of Brewed Green and Black Tea in Men With Prostate Cancer Prior to Prostatectomy + (According to the authors, there were no serious side effects associated with the intervention, no information on the recording of side effects)
Henning et al. (2015): Randomized Clinical Trial of Brewed Green and Black Tea in Men With Prostate Cancer Prior to Prostatectomy + (According to the authors, there were no serious side effects associated with the intervention, no information on the recording of side effects)
Lissoni et al. (2009): A Randomized Study of Chemotherapy versus Biochemotherapy with Chemotherapy plus Aloe arborescens in Patients with Metastatic Cancer + (Aloe was well tolerated in all patients and no metabolic undesirable effects were observed. In addition, no aloe-related toxicity occurred, including vomiting and diarrhoea.)
Barton et al. (1998): Prospective evaluation of vitamin E for hot flashes in breast cancer survivors + (As reported, no adverse effects were observed (no significant differences in headaches, nausea, fatigue, and other symptoms between placebo and Vitamin E (all p > 0.05))
Barton et al. (1998): Prospective evaluation of vitamin E for hot flashes in breast cancer survivors + (As reported, no adverse effects were observed (no significant differences in headaches, nausea, fatigue, and other symptoms between placebo and Vitamin E (all p > 0.05))
Okabayashi et al. (2020): L-Carnitine Improves Postoperative Liver Function in Hepatectomized Patients + (Authors: “L-carnitine was well tolerated by all patients.” No differences in mortality as of March 2018.)
Okabayashi et al. (2020): L-Carnitine Improves Postoperative Liver Function in Hepatectomized Patients + (Authors: “L-carnitine was well tolerated by all patients.” No differences in mortality as of March 2018.)
Hershman et al. (2013): Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy + (Caused by taxane therapy, Grade 3 Toxicities (CTCAE): Sleep disturbance: 1 instance Neuropathy (caused by taxanes): 1 instance)
Hershman et al. (2013): Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy + (Caused by taxane therapy, Grade 3 Toxicities (CTCAE): Vomiting: 1 instance Neuropathy (caused by taxanes): 8 instances)
Barton et al. (2013): The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9 + (Change in side effects of chemotherapy (scale 0-10), sign. reduction of nausea within the Ginkgo arm (Mean=-0.1, SD=2.78) compared to the placebo arm (Mean=-0.9, SD=2.67), p=0.05)
Portenoy et al. (2012): Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial + (Cognitive functions: negative effect of na … Cognitive functions: negative effect of nabiximols (no values given); nausea and vomiting; dizziness; drowsiness; disorientation; anorexia, constipation; dry mouth; anemia; diarrhea; dysgeusia headache; asthenia hallucinations; reduced appetite; fatigue; pain; insomnia; stomatitis weight lossue; pain; insomnia; stomatitis weight loss)
Portenoy et al. (2012): Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial + (Cognitive functions: negative effect of na … Cognitive functions: negative effect of nabiximols (no values given); nausea and vomiting; dizziness; drowsiness; disorientation; anorexia, constipation; dry mouth; anemia; diarrhea; dysgeusia headache; asthenia hallucinations; reduced appetite; fatigue; pain; insomnia; stomatitis; weight losse; pain; insomnia; stomatitis; weight loss)
Portenoy et al. (2012): Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial + (Cognitive functions: negative effect of na … Cognitive functions: negative effect of nabiximols (no values given); nausea and vomiting; dizziness; drowsiness; disorientation; anorexia, constipation; dry mouth; anemia; diarrhea; dysgeusia headache; asthenia hallucinations; reduced appetite; fatigue; pain; insomnia; stomatitis; weight losse; pain; insomnia; stomatitis; weight loss)
Argyriou et al. (2006): A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results + (Comparison of number of side effects p = 0.88 (mainly nausea, vomiting and hair loss), no side effects associated with vitamin E, no deaths due to vitamin E)

Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer + (Digestive disorder (n=2), migraine (n=1))

Delanian et al. (2003): Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis + (Discomfort (including hot flushes, nausea, asthenia, headaches, dizziness) in n=2)
Delanian et al. (2003): Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis + (Discomfort (including hot flushes, nausea, asthenia, headaches, dizziness) in n=4)
Delanian et al. (2003): Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis + (Discomfort (including hot flushes, nausea, asthenia, headaches, dizziness) in n=4)
Delanian et al. (2003): Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis + (Discomfort (including hot flushes, nausea, asthenia, headaches, dizziness) in n=0)
Asfour et al. (2006): Effect of high-dose sodium selenite therapy on polymorphonuclear leukocyte apoptosis in non-Hodgkin's lymphoma patients + (Gastrointestinal complaints with dizziness and occasional vomiting (was controlled with antiemetic medication) - no numbers given)
Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (Gastrointestinal symptoms, such as stage 2 heartburn, bruising/redness and skin rash)
Attia et al. (2008): Randomized, Double-Blinded Phase II Evaluation of Docetaxel with or without Doxercalciferol in Patients with Metastatic, Androgen-Independent Prostate Cancer + (Grade ≥2 creatinine, neohrolithiasis, neutropenia)
Cavallini et al. (2005): Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy + (Headache (25%), flushing (21.8%), drowsiness (9.4%), nausea (6.2%), rhinitis (6.2%), euphoria (6.2%), according to authors caused by sildenafil (no difference in side effects between both sildenafil arms))
Cavallini et al. (2005): Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy + (Headache (28.1%), flushing (22.8%), drowsiness (8.5%), rhinitis (8.5%), nausea (5.7%), according to authors caused by sildenafil (no difference in side effects between sildenafil arms))
Panahi et al. (2012): Effect of Ginger on Acute and Delayed Chemotherapy-Induced Nausea and Vomiting: A Pilot, Randomized, Open-Label Clinical Trial + (Heartburn, headache, vertigo)
Yekta et al. (2012): Ginger as a miracle against chemotherapy-induced vomiting + (Heartburn, no significant difference between arms: * anticipatory: p= 0.2 * acute: p= 0.06 * delayed: p= 0.5)
Yekta et al. (2012): Ginger as a miracle against chemotherapy-induced vomiting + (Heartburn, no significant difference between arms: * anticipatory: p= 0.2 * acute: p= 0.06 * delayed: p= 0.5)
Attia et al. (2008): Randomized, Double-Blinded Phase II Evaluation of Docetaxel with or without Doxercalciferol in Patients with Metastatic, Androgen-Independent Prostate Cancer + (Hypercalcemia, grade ≥2 calcium, nephrolithiasis, diarrhea)
Raoufinejad et al. (2019): Oral calcitriol in hematopoietic recovery and survival after autologous stem cell transplantation: a randomized clinical trial + (Hyperphosphatemia (>4.5 mg/dl) in 11/40 … Hyperphosphatemia (>4.5 mg/dl) in 11/40 (27.5%), no significant differences;hypercalcemia (>10.5 mg/dl) in 1/40 (2.5%)All side effects were “non-serious” and “mild-level-1,” except for 1/40 (2.5%) recorded as “mild-level-2” due to temporarily holding the intervention for a few doses to successfully reduce the serum calcium and phosphorous and restart calcitriolm calcium and phosphorous and restart calcitriol)
Raoufinejad et al. (2019): Oral calcitriol in hematopoietic recovery and survival after autologous stem cell transplantation: a randomized clinical trial + (Hyperphosphatemia (>4.5 mg/dl) in 12/40 … Hyperphosphatemia (>4.5 mg/dl) in 12/40 (30.0%), no significant differences;hypercalcemia (>10.5 mg/dl) in 1/40 (2.5%);All side effects were “non-serious” and “mild-level-1,” except for 3/40 (7.5%) recorded as “mild-level-2” due to temporarily holding the intervention for a few doses to successfully reduce the serum cal- cium and phosphorous and restart placeboum cal- cium and phosphorous and restart placebo)
Jatoi et al. (2002): Dronabinol Versus Megestrol Acetate Versus Combination Therapy for Cancer-Associated Anorexia: A North Central Cancer Treatment Group Study + (Impotence in 14% of men; vomiting; fluid retention; confused thinking; drowsiness; loss of coordination; inappropriate behavior)
Jatoi et al. (2002): Dronabinol Versus Megestrol Acetate Versus Combination Therapy for Cancer-Associated Anorexia: A North Central Cancer Treatment Group Study + (Impotence in 18 % of men; vomiting; fluid retention; confused thinking; drowsiness; loss of coordination; inappropriate behavior)
Jatoi et al. (2002): Dronabinol Versus Megestrol Acetate Versus Combination Therapy for Cancer-Associated Anorexia: A North Central Cancer Treatment Group Study + (Impotence in 4% of men; vomiting; fluid retention; confused thinking; drowsiness; loss of coordination; inappropriate behavior)
Iovino et al. (2018): High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ naive lymphocytes and prevents TTV reactivation + (Incidence of nausea (44.4%) and diarrhea (11.1%) was the same in the two groups, 1 patient per group had fever > 100.4 °F at home)
Iovino et al. (2018): High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ naive lymphocytes and prevents TTV reactivation + (Incidence of nausea (44.4%) and diarrhea (11.1%) was the same in the two groups, 1 patient per group had fever > 100.4 °F at home)
Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy + (Insomnia: Guarana: n = 22, placebo: n = 31, Palpitation: Guarana: n = 10, placebo: n = 12, Nausea: Guarana: n = 25, placebo: n = 35, Anxiety: Guarana: n = 17, placebo: n = 25, Dermatologic: Guarana: n = 1, placebo: n = 3)
Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy + (Insomnia: Guarana: n = 22, placebo: n = 31 … Insomnia: Guarana: n = 22, placebo: n = 31, Palpitation: Guarana: n = 10, placebo: n = 12, Nausea: Guarana: n = 25, placebo: n = 35, Anxiety: Guarana: n = 17, placebo: n = 25, Dermatologic: Guarana: n = 1, placebo: n = 3Total Guarana n=30, Placebo n=45, no statistical comparison conducted n=45, no statistical comparison conducted)
Johnson et al. (2010): Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain + (Intervention-associated events in n=106 (6 … Intervention-associated events in n=106 (60%): drowsiness, dizziness, nausea, confusion, vomiting, hypotension, hypercalcemia, increased gamma GT; Most side effects were mild/moderate; no statistical comparisons given; one case of syncope probably related to THC; other events not associated with interventioner events not associated with intervention)
Johnson et al. (2010): Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain + (Intervention-associated events in n=106 (6 … Intervention-associated events in n=106 (60%): drowsiness, dizziness, nausea, confusion, vomiting, hypotension, hypercalcemia, increased gamma GTMost side effects were mild/moderate; no statistical comparisons given; one case of syncope probably related to THC; other events not associated with interventioner events not associated with intervention)
Lissoni et al. (1998): Biotherapy with the Pineal Immunomodulating Hormone Melatonin versus Melatonin plus Aloe vera in Untreatable Advanced Solid Neoplasms + (Melatonin was well tolerated, no related toxicities.)