Property:Specifications on cancer therapies
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Hejazi et al. (2016): Effect of Curcumin Supplementation During Radiotherapy on Oxidative Status of Patients with Prostate Cancer: A Double Blinded, Randomized, Placebo-Controlled Study +
External beam radiotherapy (EBRT), in combination with hormone ablation +
Henning et al. (2015): Randomized Clinical Trial of Brewed Green and Black Tea in Men With Prostate Cancer Prior to Prostatectomy +
Study setting is prior to surgery. +
Hershman et al. (2013): Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy +
Taxan-based chemotherapy; paclitaxel 80 mg/m<sup>2</sup> once per week for 12 cycles, paclitaxel 175 mg/m<sup>2</sup> once every 2 weeks for four cycles, paclitaxel 175 mg/m<sup>2</sup> once every 2 weeks for six cycles, docetaxel 75 mg/m<sup>2</sup> once every 3 weeks for four cycles, or docetaxel 75 mg/m<sup>2</sup> once every 3 weeks for six cycles +
Hershman et al. (2018): Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L Carnitine +
Taxan-based chemotherapy; paclitaxel 80 mg/m<sup>2</sup> once per week for 12 cycles, paclitaxel 175 mg/m<sup>2</sup> once every 2 weeks for four cycles, paclitaxel 175 mg/m<sup>2</sup> once every 2 weeks for six cycles, docetaxel 75 mg/m<sup>2</sup> once every 3 weeks for four cycles, or docetaxel 75 mg/m<sup>2</sup> once every 3 weeks for six cycles +
Hodgson et al. (2012): Reflexology versus Swedish Massage to Reduce Physiologic Stress and Pain and Improve Mood in Nursing Home Residents with Cancer: A Pilot Trial. +
NI +
Hoopfer et al. (2015): Three-arm randomized phase III trial: Quality aloe and placebo cream versus powder as skin treatment during breast cancer radiation therapy +
Chemotherapy before radiotherapy per arm
Powder arm: No = 47 (59.5%); Yes = 32 (40.5%)
Aloe arm: No = 31 (38.3%); Yes = 50 (61.7%)
Placebo arm: No = 36 (46.8%); Yes = 41 (53.3%)
Surgery per arm:
Powder arm: Mastectomy = 32 (40.5%); Segmental resection = 47 (59.5%)
Aloe arm: Mastectomy = 34 (42%); Segmental resection = 47 (58%)
Placebo arm: Mastectomy = 23 (29.9%); Segmental resection = 54 (70.1%) +
Howells et al. (2011): Phase I randomised double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases - safety, pharmacokinetics and pharmacodynamics +
Resection of liver metastases +
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Inglis et al. (2020): Effects of High-Dose Vitamin D Supplementation on Phase Angle and Physical Function in Patients with Prostate Cancer on ADT +
Androgen deprivation therapy +
Iovino et al. (2018): High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ naive lymphocytes and prevents TTV reactivation +
After stem cell transplantation +
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Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study +
Fluorouracil 500 mg/m<sup>2</sup> , epirubicin 100 mg/m<sup>2</sup> and cyclophosphamide 500 mg/m<sup>2</sup> (FEC) i.v. on day 1 every 21 days for three cycles, followed by docetaxel 100 mg/m2 i.v. on day 1 every 21 days for three cycles;
Docetaxel - 2 cyclophosphamide, methotrexate, 5-fluorouracile;
Trastuzumab +
Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial +
The high-dose chemotherapy included busulfan 4 mg/kg p.o. in divided doses daily for 4 days (total dose 16 mg/kg) followed by cyclophsophamide 60 mg/kg once daily i.v. for 2 days (total dose 120 mg/kg) + peripheral blood hematopoietic stem cells 1 day after completion of chemotherapy +
Jatoi et al. (2002): Dronabinol Versus Megestrol Acetate Versus Combination Therapy for Cancer-Associated Anorexia: A North Central Cancer Treatment Group Study +
Planned concurrent chemotherapy, %, per arm
* None: Megestrol Acetate = 30; Dronabinol = 30; Megestrol Acetate + Dronabinol= 30
* With cisplatinum: Megestrol Acetate = 15; Dronabinol = 14; Megestrol Acetate + Dronabinol = 14
* Without cisplatinum: Megestrol Acetate= 55; Dronabinol = 56; Megestrol Acetate + Dronabinol = 56
Planned concurrent radiation, %
* Yes: Megestrol Acetate = 21; Dronabinol = 20; Megestrol Acetate + Dronabinol = 20
* No: Megestrol Acetate = 79; Dronabinol = 80; Megestrol Acetate + Dronabinol = 80 +
Jeon et al. (2016): Effect of intravenous high dose Vitamin C on postoperative pain and morphine use after laparoscopic colectomy: A randomized controlled trial +
Elective laparoscopic colectomy +
Johansson et al. (2021): Vitamin D Supplementation and Disease-Free Survival in Stage II Melanoma: A Randomized Placebo Controlled Trial +
NI +
Johnson et al. (2010): Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain +
No therapy in the last 2 weeks +
Jyothirmayi et al. (1996): Efficacy of Vitamin A in the Prevention of Locoregional Recurrence and Second Primaries in Head and Neck Cancer +
Previous treatment per group:
- intervention: 44x radiotherapy, 3x surgery, 3x radiotherapy + surgery
- placebo: 47x radiotherapy, 5x surgery, 4x radiotherapy + surgery +
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Kadhim et al. (2021): Effect of Ginger Tea on Chemotherapy-Induced Nausea and Vomiting among Patients Attending the Oncology Teaching Hospital, Baghdad 2020 +
? +
Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597 +
NA +
Kasseroller et al. (2003): Efficacy and tolerability of proteolytic enzymes as an anti-inflammatory agent in lymphoedema after axillary dissection due to mammary cancer +
All patients got axillary dissection due to mammary cancer and receive now combined decongestive therapy (CDT) for the lymphoedema. +