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Property:Specifications on cancer therapies

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Taxan-based chemotherapy; paclitaxel 80 mg/m<sup>2</sup> once per week for 12 cycles, paclitaxel 175 mg/m<sup>2</sup> once every 2 weeks for four cycles, paclitaxel 175 mg/m<sup>2</sup> once every 2 weeks for six cycles, docetaxel 75 mg/m<sup>2</sup> once every 3 weeks for four cycles, or docetaxel 75 mg/m<sup>2</sup> once every 3 weeks for six cycles  +
Taxan-based chemotherapy; paclitaxel 80 mg/m<sup>2</sup> once per week for 12 cycles, paclitaxel 175 mg/m<sup>2</sup> once every 2 weeks for four cycles, paclitaxel 175 mg/m<sup>2</sup> once every 2 weeks for six cycles, docetaxel 75 mg/m<sup>2</sup> once every 3 weeks for four cycles, or docetaxel 75 mg/m<sup>2</sup> once every 3 weeks for six cycles  +
Chemotherapy before radiotherapy per arm Powder arm: No = 47 (59.5%); Yes = 32 (40.5%) Aloe arm: No = 31 (38.3%); Yes = 50 (61.7%) Placebo arm: No = 36 (46.8%); Yes = 41 (53.3%) Surgery per arm: Powder arm: Mastectomy = 32 (40.5%); Segmental resection = 47 (59.5%) Aloe arm: Mastectomy = 34 (42%); Segmental resection = 47 (58%) Placebo arm: Mastectomy = 23 (29.9%); Segmental resection = 54 (70.1%)  +
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J
Fluorouracil 500 mg/m<sup>2</sup> , epirubicin 100 mg/m<sup>2</sup> and cyclophosphamide 500 mg/m<sup>2</sup> (FEC) i.v. on day 1 every 21 days for three cycles, followed by docetaxel 100 mg/m2 i.v. on day 1 every 21 days for three cycles; Docetaxel - 2 cyclophosphamide, methotrexate, 5-fluorouracile; Trastuzumab  +
The high-dose chemotherapy included busulfan 4 mg/kg p.o. in divided doses daily for 4 days (total dose 16 mg/kg) followed by cyclophsophamide 60 mg/kg once daily i.v. for 2 days (total dose 120 mg/kg) + peripheral blood hematopoietic stem cells 1 day after completion of chemotherapy  +
Planned concurrent chemotherapy, %, per arm * None: Megestrol Acetate = 30; Dronabinol = 30; Megestrol Acetate + Dronabinol= 30 * With cisplatinum: Megestrol Acetate = 15; Dronabinol = 14; Megestrol Acetate + Dronabinol = 14 * Without cisplatinum: Megestrol Acetate= 55; Dronabinol = 56; Megestrol Acetate + Dronabinol = 56 Planned concurrent radiation, % * Yes: Megestrol Acetate = 21; Dronabinol = 20; Megestrol Acetate + Dronabinol = 20 * No: Megestrol Acetate = 79; Dronabinol = 80; Megestrol Acetate + Dronabinol = 80  +
Previous treatment per group: - intervention: 44x radiotherapy, 3x surgery, 3x radiotherapy + surgery - placebo: 47x radiotherapy, 5x surgery, 4x radiotherapy + surgery  +
K
All patients got axillary dissection due to mammary cancer and receive now combined decongestive therapy (CDT) for the lymphoedema.  +