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- Van Zandwijk et al. (2000): EUROSCAN, a Randomized Trial of Vitamin A and N-Acetylcysteine in Patients With Head and Neck Cancer or Lung Cancer + (PRO: * Large sample according to power an … PRO: </br>* Large sample according to power analysis </br>CONTRA: </br>* No blinding </br>* No p-values for baseline group differences -> at least descriptively partially different </br>* More treatment dropouts in vitamin A groups (vit. A: 26%/vit. A+NAC: 25% vs. NAC: 18%; p < 0.001)</br>* Very unclear reporting, only very few p-values reported overallporting, only very few p-values reported overall)