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List of results

• Stephenson et al. (2000): The Effects of Foot Reflexology on Anxiety and Pain in Patients With Breast and Lung Cancer.  + (Mean (SD) = 68.7 (2.69))
• Johnson et al. (2010): Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain  + (Mean (SD) Age: 60.2 (12.3) years)
• Portenoy et al. (2012): Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial  + (Mean (SD) age = 58 (12.2) years Range = 20-93 years)
• Jatoi et al. (2002): Dronabinol Versus Megestrol Acetate Versus Combination Therapy for Cancer-Associated Anorexia: A North Central Cancer Treatment Group Study  + (Mean (SD) age per arm: * Megestrol Acetate = 65 (11) years * Dronabinol = 67 (10) years * Megestrol Acetate + Dronabinol = 67 (10) years)
• Lichtmann et al. (2018): Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain  + (Mean (SD) age per arm: Intervention arm = 59.2 (12) years Placebo arm = 60.7 (11.1) years)
• Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies  + (Mean (SD) age per arm: Sativex = 60 (11) years Placebo = 59.6 (11) years)
• Bairati et al. (2005): A Randomized Trial of Antioxidant Vitamins to Prevent Second Primary Cancers in Head and Neck Cancer Patients  + (Mean (SD) in years per arm: - intervention: 62.9 (10.0) - placebo: 62.3 (9.5))
• Bairati et al. (2005): Randomized Trial of Antioxidant Vitamins to Prevent Acute Adverse Effects of Radiation Therapy in Head and Neck Cancer Patients  + (Mean (SD) in years per arm: - intervention: 62.9 (10.0) - placebo: 62.3 (9.5))
• Bairati et al. (2006): Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients  + (Mean (SD) in years per arm: - intervention: 62.9 (10.0) - placebo: 62.3 (9.5))
• Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial  + (Mean (SD) intervention vs. placebo: 57 (14) vs. 59 (11) years)
• Bossi et al. (2017): A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin  + (Mean (SD) intervention vs. placebo: 58.8 (10.4) vs. 59.5 (10.0) years)
• Jeon et al. (2016): Effect of intravenous high dose Vitamin C on postoperative pain and morphine use after laparoscopic colectomy: A randomized controlled trial  + (Mean (SD) per group: - placebo: 64.5 (10.6) years - intervention: 65.4 (9.6) years)
• Muecke et al. (2013): Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology-a subgroup analysis of a multicenter, phase III trial  + (Mean (SD), range): 64.3 (10.1); 31–80 years)
• Muecke et al. (2010): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology  + (Mean (SD), range: 64.3 (10.1), 31–80 years)
• Wyatt et al. (2017): A Randomized Clinical Trial of Caregiver-Delivered Reflexology for Symptom Management During Breast Cancer Treatment  + (Mean (SD): Reflexology arm: 58.09 (11.62) Control arm: 54.80 (10.30))
• Özdelikara et al. (2017): The effect of reflexology on the quality of life with breast cancer patients  + (Mean (SD): 51 (11.12))
• Özdelikara et al. (2017): The Effect of Reflexology on Chemotherapy-induced Nausea, Vomiting, and Fatigue in Breast Cancer Patients  + (Mean (SD): 51 years (11.12))
• Mansourian et al. (2015): The effect of "curcuma Longa" topical gel on radiation -induced oral mucositis in patients with head and neck cancer  + (Mean (SD): 51.34 (12.08) years)
• Del Giglio (2013): Purified Dry Extract of Paullinia cupana (Guarana) (PC-18) for Chemotherapy-Related Fatigue in Patients with Solid Tumors: An Early Discontinuation Study  + (Mean (SD): 55.9 years (13.0))
• Ripamonti et al. (1998): A randomized, controlled clinical trial to evaluate the effects of zinc sulfate on cancer patients with taste alterations caused by head and neck irradiation  + (Mean (SD): 57.9 (12.81))
• Najafizade et al. (2013): Preventive effects of zinc sulfate on taste alterations in patients under irradiation for head and neck cancers: A randomized placebo-controlled trial  + (Mean (SD): 59.2 (16.5))
• Shapiro et al. (2016): Randomized, blinded trial of vitamin D3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS)  + (Mean (SD): 60.9 (8.8))
• Nasser et al. (2017): Vitamin D ointment for prevention of radiation dermatitis in breast cancer patients  + (Mean (SD): 63 (8), range: 37-74)
• Kraft et al. (2012): L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial  + (Mean (SD): 64.4 (1.7) years)
• Cruciani et al. (2009): L-Carnitine Supplementation in Patients with Advanced Cancer and Carnitine Deficiency: A Double-Blind, Placebo-Controlled Study  + (Mean (SD): 66–70 (13) years)

• Akiba et al. (2018): Vitamin D Supplementation and Survival of Patients with Non–small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial  + (Mean (SD): 68 (9))

• Koyama et al. (2017): Intravenous Carnitine Administration in Addition to Parenteral Nutrition With Lipid Emulsion May Decrease the Inflammatory Reaction in Postoperative Surgical Patients  + (Mean (SD): 68 (9.6) years)
• Hejazi et al. (2013): A pilot clinical trial of radioprotective effects of curcumin supplementation in patients with prostate cancer  + (Mean (SD): 70.74 (8.21) years)
• Hejazi et al. (2016): Effect of Curcumin Supplementation During Radiotherapy on Oxidative Status of Patients with Prostate Cancer: A Double Blinded, Randomized, Placebo-Controlled Study  + (Mean (SD): 70.74 (8.21) years)
• Dyer et al. (2013): Is reflexology as effective as aromatherapy massage for symptom relief in an adult outpatient oncology population?  + (Mean (SD): Arm A: 53.76 (11.36); Arm B: 54.72 (11.12))
• Rao et al. (2014): The Indian Spice Turmeric Delays and Mitigates Radiation-Induced Oral Mucositis in Patients Undergoing Treatment for Head and Neck Cancer: An Investigational Study  + (Mean (SD, range) = 55.96 (12.25, 26-85) years)
• Ansari et al. (2016): Efficacy of Ginger in Control of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients Receiving Doxorubicin- Based Chemotherapy  + (Mean (range) in years: 48.6 (25-79))
• Ehrenpreis et al. (2005): A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy  + (Mean (range): 66 (50-87))
• Hershman et al. (2013): Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy  + (Mean (range): intervention arm 52 (27-80) years; placebo arm 50 (26-77) years)
• Wyatt et al. (2012): Health-Related Quality-of-Life Outcomes: A Reflexology Trial With Patients With Advanced-Stage Breast Cancer  + (Mean = 56 years)
• Stephenson et al. (2017): Partner-delivered reflexology: Effects on cancer pain and anxiety.  + (Mean = 58.3)
• Uysal et al. (2016): Effects of foot massage applied in two different methods on symptom control in colorectal cancer patients: Randomised control trial  + (Mean = 59 years)
• Hoopfer et al. (2015): Three-arm randomized phase III trial: Quality aloe and placebo cream versus powder as skin treatment during breast cancer radiation therapy  + (Mean age (SD) per arm: Powder arm = 79 (33.3) years Aloe arm = 81 (34.2) years Placebo arm = 77 (32.5) years)
• Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects  + (Mean age (SD) per arm: Enyzme arm: 49.9 (10.5) years Control arm: 49.3 (13.9) years)
• Vinzenz et al. (1992): Die Therapie der radiogenen Mukositis mit Enzymen  + (Mean age (SD) per arm: Enzyme arm: 51.5 (8.7) Control arm: 56.4 (6.7))
• Gujral et al. (2001): Efficacy of hydrolytic enzymes in preventing radiation therapy-induced side effects in patients with head and neck cancers  + (Mean age (SD) per arm: Enzyme-arm: 50.3 (9.4) years Control-arm: 51.2 (11.2) years)
• Dörr et al. (2007): Efficacy of Wobe-Mugos E for Reduction of Oral Mucositis after Radiotherapy  + (Mean age (SD) per arm: Enzyme-arm: 57.6 (7.8) years Placebo-arm: 58.8 (9.0) years)
• Henning et al. (2015): Randomized Clinical Trial of Brewed Green and Black Tea in Men With Prostate Cancer Prior to Prostatectomy  + (Mean age (SD) per arm: Green tea arm: 62.1 (6.9) years Black tea arm: 61.4 (7.4) years Water arm: 62.8 (6.2) years)
• Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy  + (Mean age (SD) per arm: Green tea arm: 65.7 (9.3) years, placebo arm: 58.7 (13.6) years)
• Mansouri et al. (2016): The Effect of Aloe Vera Solution on Chemotherapy-Induced Stomatitis in Clients with Lymphoma and Leukemia: A Randomized Controlled Clinical Trial  + (Mean age (SD) per arm: Aloe arm: 46.25(18.17) years Placebo arm: 47.78(18.28) years)
• Sahebjamee et al. (2015): Comparative Efficacy of Aloe vera and Benzydamine Mouthwashes on Radiation-induced Oral Mucositis: A Triple-blind, Randomised, Controlled Clinical Trial  + (Mean age (SD) per arm: Aloe arm: 55.38 (17.99) years Placebo arm: 59.31 (15.03) years)
• Tan et al. (2018): Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor  + (Mean age (SD) per arm: Enzyme arm: 24.35 (5.57) years Control arm: 23.76 (5.48) years)
• Stauder et al. (1991): Strahlentherapeutische Nebenwirkungen bei Abdominalkrebspatienten und deren Reduktion durch hydrolytische Enzyme  + (Mean age (SD) per arm: Enzyme-arm: 62.0 (11.3) years Control-arm: 64.5 (9.3) years)
• Puataweepong et. al (2009): The efficacy of oral Aloe vera juice for radiation induced mucositis in head and neck cancer patients: a double-blind placebo-controlled study  + (Mean age (min-max) per year: Aloe arm: 60 (38-91) years Placebo arm: 54 (31-84) years)
• Lissoni et al. (1998): Biotherapy with the Pineal Immunomodulating Hormone Melatonin versus Melatonin plus Aloe vera in Untreatable Advanced Solid Neoplasms  + (Mean age (range) per arm: Aloe arm: 63 (48-80) years Placebo arm: 61 (46-79) years)
• Strasser et al. (2006): Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled (…)  + (Mean age = 61 years Mean (SD) age per arm: THC = 60 (12) years Cannabis extract = 61 (12) years Placebo = 62 (10) years)