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- Cruciani et al. (2009): L-Carnitine Supplementation in Patients with Advanced Cancer and Carnitine Deficiency: A Double-Blind, Placebo-Controlled Study + (14 days, then L-Carnitine 2g (2x 1g) daily for 14 days)
- Sahebnasagh et al. (2017): Successful Treatment of Acute Radiation Proctitis with Aloe Vera: A Preliminary Randomized Controlled Clinical Trial + (1g Aloe ointment (3% aloe powder, 2.3% white paraffin, 94.7% Vaseline) rectally 2x daily for 4 weeks. + all patients: 500mg Sulfasalazine 4x per day + all patients: radiotherapy)
- Sahebnasagh et al. (2017): Successful Treatment of Acute Radiation Proctitis with Aloe Vera: A Preliminary Randomized Controlled Clinical Trial + (1g Placebo ointment (without aloe vera) rectally 2x daily for 4 weeks + all patients: 500mg Sulfasalazine 4x per day + all patients: radiotherapy)
- Azizi et al. (2015): Efficacy of Topical and Systemic Vitamin E in Preventing Chemotherapy-induced Oral Mucositis + (1g; 2x daily Duration: day -2 chemotherapy until 20 days after the end of the chemotherapy cycle for 4 chemotherapy cycles)
- Azizi et al. (2015): Efficacy of Topical and Systemic Vitamin E in Preventing Chemotherapy-induced Oral Mucositis + (1g; 2x daily Duration: day -2 chemotherapy until 20 days after the end of the chemotherapy cycle for 4 chemotherapy cycles)
- Van Zandwijk et al. (2000): EUROSCAN, a Randomized Trial of Vitamin A and N-Acetylcysteine in Patients With Head and Neck Cancer or Lung Cancer + (1st year: retinyl palmitate (300,000 IU) 1x/day 2nd year: retinyl palmitate (150,000 IU) 1x/day)
- Goossens et al. (2016): Phase III randomised chemoprevention study with selenium on the recurrence of non-invasive urothelial carcinoma. The SELEnium and BLAdder cancer Trial + (1x per day)
- Sontakke et al. (2003): Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: A randomized, cross-over, double blind study + (2 capsules of lactulose orally and injection ondansetron 4 mg IV, 20 min prior to chemotherapy and two capsules of ondansetron, 2 mg each, orally after 6 h.)
- Sontakke et al. (2003): Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: A randomized, cross-over, double blind study + (2 capsules of lactulose orally and injection metoclopramide 20 mg IV, 20 min prior to chemotherapy. Two capsules of 5 mg metoclopramide each, orally after 6 h)
- Dos Santos Martins (2016): Placebo-Controlled, Double-Blind, Randomized Study of a Dry Guarana Extract in Patients with Head and Neck Tumors Undergoing Chemoradiotherapy: Effects on Fatigue and Quality of Life + (2 daily doses before meals, During 6 weeks of chemotherapy)
- Dos Santos Martins (2016): Placebo-Controlled, Double-Blind, Randomized Study of a Dry Guarana Extract in Patients with Head and Neck Tumors Undergoing Chemoradiotherapy: Effects on Fatigue and Quality of Life + (2 daily doses before meals, 100 mg, , D160314, with 7.4% caffeine content, manufactured by PharmaNostra During 6 weeks of chemotherapy)
- Braga et al. (2015): Effect of Zinc Supplementation on Serological Response to Vaccination Against Streptococcus Pneumoniae in Patients Undergoing Chemotherapy for Colorectal Cancer + (2 placebo capsules/ day (composed of wheat … 2 placebo capsules/ day (composed of wheat starch with no added zinc)</br>+ vaccination with 1 dose of 0.5 mL of 23-valent pneumococcal polysaccharide vaccine (Pneumovax 23 , Merck, Whitehouse Station, NJ), containing 25 mg of capsular polysaccharide antigen from 23 different pneumococcal serotypes (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F); 2 days after zinc supplementation started 2 days after zinc supplementation started)
- Braga et al. (2015): Effect of Zinc Supplementation on Serological Response to Vaccination Against Streptococcus Pneumoniae in Patients Undergoing Chemotherapy for Colorectal Cancer + (2 zinc sulfate capsules/ day (each contain … 2 zinc sulfate capsules/ day (each containing 35 mg of elemental zinc); first capsule 1h after breakfast and the other 1h after dinner</br>+ vaccination with 1 dose of 0.5 mL of 23-valent pneumococcal polysaccharide vaccine (Pneumovax 23 , Merck, Whitehouse Station, NJ), containing 25 mg of capsular polysaccharide antigen from 23 different pneumococcal serotypes (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F); 2 days after zinc supplementation started 2 days after zinc supplementation started)
- Strasser et al. (2006): Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled (…) + (2,5mg THC + 1mg cannabidiol, 2x a day, preferably taken before lunch and dinner/at bedtime)
- Zick et al. (2008): Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting + (2.0-g ginger dose - Each capsule contained 250 mg dry extract of ginger root [10:1 (v/v) extraction solvent (ethanol 50%)/root] standardized to 15 mg (5%) of total gingerols - 8 capsuels daily)
- Strasser et al. (2006): Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled (…) + (2.5mg THC orally, 2x a day, preferably taken before lunch and dinner/at bedtime)
- Goossens et al. (2016): Phase III randomised chemoprevention study with selenium on the recurrence of non-invasive urothelial carcinoma. The SELEnium and BLAdder cancer Trial + (200 µg 1x per day, orally)
- Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597 + (200 µg daily)
- Stratton et al. (2010): Oral Selenium Supplementation Has No Effect on Prostate- Specific Antigen Velocity in Men Undergoing Active Surveillance for Localized Prostate Cancer + (200 μg selenium per day (yeast selenium); Follow-up duration (mean (SD); median): 33.4 (20.3); 33.3 years)
- Yap et al. (2017): Predictors of hand-foot syndrome and pyridoxine for prevention of capecitabine-induced hand-foot syndrome: a randomized clinical trial + (200mg daily for maximum of 8 cycles of 3 weeks each, from start of chemotherapy)
- Scher et al. (2011): Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer + (21-day dosing cycles with 5-mg oral prednisone twice daily)
- Yekta et al. (2012): Ginger as a miracle against chemotherapy-induced vomiting + (250 mg dry powered ginger root and included 5.38 mg (2.15%) 6-gingerol, 1.8 mg (0.72%) 8-gingerol, 4.19 mg (1.78%) 10-gingerol, and 0.92 mg (0.37%) 6-shagaol 6 days starting 3 days before the chemotherapy session)
- Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (250mg 2x3 ginger capsules (liquid extract from ginger root in virgin olive oil + excipients, 1.5g ginger daily) 1.5g daily)
- Scher et al. (2011): Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer + (28-day dosing cycles of 45-μg oral DN-101 on days 1, 8, and 15, continue DN-101 for up to 48 weeks or until unacceptable DN-101 toxicity or experimental agents were initiated)
- Cruciani et al. (2012): L-Carnitine Supplementation for the Management of Fatigue in Patients With Cancer: An Eastern Cooperative Oncology Group Phase III, Randomized, Double-Blind, Placebo-Controlled Trial + (2g (2x 1g) daily oral Duration: 8 weeks)
- Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer + (2x 15mg daily)