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- Dos Santos Martins (2016): Placebo-Controlled, Double-Blind, Randomized Study of a Dry Guarana Extract in Patients with Head and Neck Tumors Undergoing Chemoradiotherapy: Effects on Fatigue and Quality of Life + (2 daily doses before meals, 100 mg, , D160314, with 7.4% caffeine content, manufactured by PharmaNostra During 6 weeks of chemotherapy)