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List of results

Sontakke et al. (2003): Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: A randomized, cross-over, double blind study + (2 capsules of lactulose orally and injection ondansetron 4 mg IV, 20 min prior to chemotherapy and two capsules of ondansetron, 2 mg each, orally after 6 h.)
Sontakke et al. (2003): Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: A randomized, cross-over, double blind study + (2 capsules of lactulose orally and injection metoclopramide 20 mg IV, 20 min prior to chemotherapy. Two capsules of 5 mg metoclopramide each, orally after 6 h)
Dos Santos Martins (2016): Placebo-Controlled, Double-Blind, Randomized Study of a Dry Guarana Extract in Patients with Head and Neck Tumors Undergoing Chemoradiotherapy: Effects on Fatigue and Quality of Life + (2 daily doses before meals, During 6 weeks of chemotherapy)
Dos Santos Martins (2016): Placebo-Controlled, Double-Blind, Randomized Study of a Dry Guarana Extract in Patients with Head and Neck Tumors Undergoing Chemoradiotherapy: Effects on Fatigue and Quality of Life + (2 daily doses before meals, 100 mg, , D160314, with 7.4% caffeine content, manufactured by PharmaNostra During 6 weeks of chemotherapy)
Braga et al. (2015): Effect of Zinc Supplementation on Serological Response to Vaccination Against Streptococcus Pneumoniae in Patients Undergoing Chemotherapy for Colorectal Cancer + (2 placebo capsules/ day (composed of wheat … 2 placebo capsules/ day (composed of wheat starch with no added zinc)+ vaccination with 1 dose of 0.5 mL of 23-valent pneumococcal polysaccharide vaccine (Pneumovax 23 , Merck, Whitehouse Station, NJ), containing 25 mg of capsular polysaccharide antigen from 23 different pneumococcal serotypes (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F); 2 days after zinc supplementation started 2 days after zinc supplementation started)
Braga et al. (2015): Effect of Zinc Supplementation on Serological Response to Vaccination Against Streptococcus Pneumoniae in Patients Undergoing Chemotherapy for Colorectal Cancer + (2 zinc sulfate capsules/ day (each contain … 2 zinc sulfate capsules/ day (each containing 35 mg of elemental zinc); first capsule 1h after breakfast and the other 1h after dinner+ vaccination with 1 dose of 0.5 mL of 23-valent pneumococcal polysaccharide vaccine (Pneumovax 23 , Merck, Whitehouse Station, NJ), containing 25 mg of capsular polysaccharide antigen from 23 different pneumococcal serotypes (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F); 2 days after zinc supplementation started 2 days after zinc supplementation started)
Strasser et al. (2006): Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled (…) + (2,5mg THC + 1mg cannabidiol, 2x a day, preferably taken before lunch and dinner/at bedtime)
Zick et al. (2008): Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting + (2.0-g ginger dose - Each capsule contained 250 mg dry extract of ginger root [10:1 (v/v) extraction solvent (ethanol 50%)/root] standardized to 15 mg (5%) of total gingerols - 8 capsuels daily)
Strasser et al. (2006): Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled (…) + (2.5mg THC orally, 2x a day, preferably taken before lunch and dinner/at bedtime)
Goossens et al. (2016): Phase III randomised chemoprevention study with selenium on the recurrence of non-invasive urothelial carcinoma. The SELEnium and BLAdder cancer Trial + (200 µg 1x per day, orally)
Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597 + (200 µg daily)
Stratton et al. (2010): Oral Selenium Supplementation Has No Effect on Prostate- Specific Antigen Velocity in Men Undergoing Active Surveillance for Localized Prostate Cancer + (200 μg selenium per day (yeast selenium); Follow-up duration (mean (SD); median): 33.4 (20.3); 33.3 years)
Yap et al. (2017): Predictors of hand-foot syndrome and pyridoxine for prevention of capecitabine-induced hand-foot syndrome: a randomized clinical trial + (200mg daily for maximum of 8 cycles of 3 weeks each, from start of chemotherapy)
Scher et al. (2011): Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer + (21-day dosing cycles with 5-mg oral prednisone twice daily)
Yekta et al. (2012): Ginger as a miracle against chemotherapy-induced vomiting + (250 mg dry powered ginger root and included 5.38 mg (2.15%) 6-gingerol, 1.8 mg (0.72%) 8-gingerol, 4.19 mg (1.78%) 10-gingerol, and 0.92 mg (0.37%) 6-shagaol 6 days starting 3 days before the chemotherapy session)
Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (250mg 2x3 ginger capsules (liquid extract from ginger root in virgin olive oil + excipients, 1.5g ginger daily) 1.5g daily)
Scher et al. (2011): Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer + (28-day dosing cycles of 45-μg oral DN-101 on days 1, 8, and 15, continue DN-101 for up to 48 weeks or until unacceptable DN-101 toxicity or experimental agents were initiated)
Cruciani et al. (2012): L-Carnitine Supplementation for the Management of Fatigue in Patients With Cancer: An Eastern Cooperative Oncology Group Phase III, Randomized, Double-Blind, Placebo-Controlled Trial + (2g (2x 1g) daily oral Duration: 8 weeks)
Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer + (2x 15mg daily)
Konmun et al. (2017): A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy + (2x 2 Placebo capsules daily, from 3 days before chemotherapy for 12 weeks or until the end of chemotherapy)
Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer + (2x 200 mcg tablets of selenium (Webber Naturals, Coquitlam, BC, Canada) daily from the first day until the end of radiation (including days without radiation exposure))
Strasser et al. (2006): Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled (…) + (2x a day, preferably taken before lunch and dinner/at bedtime)
Barton et al. (2013): The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9 + (2x daily)
Mix et al. (2015): Randomized phase II trial of selenomethionine as a modulator of efficacy and toxicity of chemoradiation in squamous cell carcinoma of the head and neck + (2x daily 7 days before chemotherapy, during chemotherapy 1x daily, and daily for 3 weeks after chemotherapy)
Wrbka et al. (1987): Unterstützung der Chemotherapie inoperabler Karzinome durch proteolytische Fermente + (2x daily Wobe Mugos microclysms, 5g each, for 1 to 4 weeks (average 2 weeks) and further outpatient treatment with dragees + all patients: Poly-chemotherapy (Fluoro-Uracil, Vinblastin, Metothrexat, Cyclophosphamid))
Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer + (2x placebo tablets daily from the first day until the end of radiation (including days without radiation exposure))

Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy + (2x/day, every 12 hours (50 mg, Charge E16117007))
Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy + (2x/day, every 12 hours (50 mg, Charge E16117007))

Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (2x1 placebo capsules 250mg 2x2 ginger capsules ((liquid extract from ginger root in virgin olive oil + excipients and placebo capsules, 1.0g ginger daily))
Konmun et al. (2017): A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy + (2x2 6-gingerol capsules daily (5mg each, standardized), from 3 days before chemotherapy for 12 weeks or until the end of chemotherapy)
Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (2x2 placebo capsules 250mg 2x1 ginger capsules (liquid extract from ginger root in virgin olive oil + excipients and placebo capsules, 0.5g ginger daily))
Li et al. (2018): Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial + (2x250 mg every 12 hours from the first day of chemotherapy)
Li et al. (2018): Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial + (2x250mg (5% gingerol) every 12 hours from the first day of chemotherapy)
Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (2x3 placebo capsules)
Ryan et al. (2013): Curcumin for radiation dermatitis: a randomized, double-blind, placebo-controlled clinical trial of thirty breast cancer patients + (3 times daily, 4 capsules each time Duration: 7 weeks (entire radiationtherapy))
Pace et al. (2003): Neuroprotective Effect of Vitamin E Supplementation in Patient Treated With Cisplatin Chemotherapy + (300 mg daily, orally Start: before chemotherapy (Median: 4 days prior (Range: 1-8)) Duration: until 3 months post-chemotherapy)
Wyatt et al. (2012): Health-Related Quality-of-Life Outcomes: A Reflexology Trial With Patients With Advanced-Stage Breast Cancer + (30min., 1x week, 4 weeks in total)
Wyatt et al. (2012): Health-Related Quality-of-Life Outcomes: A Reflexology Trial With Patients With Advanced-Stage Breast Cancer + (30min., 1x week, 4 weeks in total)
Wyatt et al. (2012): Health-Related Quality-of-Life Outcomes: A Reflexology Trial With Patients With Advanced-Stage Breast Cancer + (30min., 1x week, 4 weeks in total)
Del Giglio (2013): Purified Dry Extract of Paullinia cupana (Guarana) (PC-18) for Chemotherapy-Related Fatigue in Patients with Solid Tumors: An Early Discontinuation Study + (37.5 mg by mouth, 2x/day Starting after 1 week of chemotherapy, for 3 weeks Depending on the improvement or stabilization of the BFI scores: randomized assignment to a placebo for another 3 weeks)
Del Giglio (2013): Purified Dry Extract of Paullinia cupana (Guarana) (PC-18) for Chemotherapy-Related Fatigue in Patients with Solid Tumors: An Early Discontinuation Study + (37.5 mg by mouth, 2x/day Starting after 1 week of chemotherapy, for 3 weeks Depending on the improvement or stabilization of the BFI scores: randomized assignment to either the continuation of PC-18 at the same dose)
Hershman et al. (2018): Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L Carnitine + (3g (6 capsules each (hydrochloride, cellulose, 500mg ALC)) daily for 24 weeks)
Hershman et al. (2013): Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy + (3g (6 capsules each (hydrochloride, cellulose, 500mg ALC)) daily for 24 weeks)
Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer + (3x 1g daily + 549mg)
Arbabi-kalati et al. (2012): Evaluation of the efficacy of zinc sulfate in the prevention of chemotherapy-induced mucositis: A double-blind randomized clinical trial + (3x 220mg zinc sulfate capsules, daily)
Heggie et al. (2002): A phase III study on the efficacy of topical aloe vera gel on irradiated breast tissue + (3x daily (including immediately after trea … 3x daily (including immediately after treatment on treatment days) topical aqueous cream on the irradiated breast during and for 2 weeks after radiation therapy+ all patients: routine skin care recommendations: using only mild baby soap on the treatment site, airing skin twice daily, and wearing loose cotton clothing next to treated skin+ all patients: radiation therapyed skin + all patients: radiation therapy)
Heggie et al. (2002): A phase III study on the efficacy of topical aloe vera gel on irradiated breast tissue + (3x daily (including immediately after trea … 3x daily (including immediately after treatment on treatment days) topical 98% aloe vera gel on the irradiated breast during and for 2 weeks after radiation therapy+ all patients: routine skin care recommendations: using only mild baby soap on the treatment site, airing skin twice daily, and wearing loose cotton clothing next to treated skin+ all patients: radiation therapyed skin + all patients: radiation therapy)
Arbabi-kalati et al. (2012): Evaluation of the efficacy of zinc sulfate in the prevention of chemotherapy-induced mucositis: A double-blind randomized clinical trial + (3x placebo capsules, daily (similar in shape, taste, and color))
Gujral et al. (2001): Efficacy of hydrolytic enzymes in preventing radiation therapy-induced side effects in patients with head and neck cancers + (3x3 tablets WOBE-MUGOS E (10mg papain, 40m … 3x3 tablets WOBE-MUGOS E (10mg papain, 40mg trypsin, 40mg chymotrypsin) daily, starting 3 days before the first radiotherapy treatment over a period of 54(+/-9) days until 5 days after completion of radiation therapy+ all patients received 50 to 70 Gy telecobalt therapy using a standard daily radiation dose of 2 Gy in 25-35 fractions over a period of 6-7 weeks25-35 fractions over a period of 6-7 weeks)
Martin et al. (2002): Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial + (3x4 capsules of of WOBE-MUGOS containing e … 3x4 capsules of of WOBE-MUGOS containing each 100 mg papain (270 FIPE), 40 mg trypsin (29 ukat) and 40 mg chymotrypsin (200 ukat) daily, starting 3 days before irradiation and finishing on the last day of radiotherapy+ all patients: radiation using a four-field box technique with individually shaped blocks; external beam radiotherapy was given using fractionation of 5 x 1.8 Gy weekly to a total dose of 50.4 Gy, specified at the isocentreose of 50.4 Gy, specified at the isocentre)
Martin et al. (2002): Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial + (3x4 capsules without any enzyme contentsda … 3x4 capsules without any enzyme contentsdaily, starting 3 days before irradiation and finishing on the last day of radiotherapy+ all patients: radiation using a four-field box technique with individually shaped blocks; external beam radiotherapy was given using fractionation of 5 x 1.8 Gy weekly to a total dose of 50.4 Gy, specified at the isocentreose of 50.4 Gy, specified at the isocentre)
Dörr et al. (2007): Efficacy of Wobe-Mugos E for Reduction of Oral Mucositis after Radiotherapy + (3x4 tablets of WOBE-MUGOS E daily, startin … 3x4 tablets of WOBE-MUGOS E daily, starting 3 days before the first radiotherapy dose until 5 days after the last dose of radiotherapy.The verum (Wobe-Mugos E) contained papain 100 mg, trypsin 40 mg, and chymotrypsin 40 mg.+ all participants: Radiotherapy protocols comprised conventional fractionation with 1.8–2.0 Gy/fraction, 5× per week to total doses of 60–66 Gy per 6–7 weeks, or hyperfractionation with 2 × 1.2 Gy per day, 5× per week to a total dose of 72 Gy per 6–7 weeks.Hyperfractionation was applied in 8 (22%) patients in the Wobe-Mugos E armn 8 (22%) patients in the Wobe-Mugos E arm)