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- Kasseroller et al. (2003): Efficacy and tolerability of proteolytic enzymes as an anti-inflammatory agent in lymphoedema after axillary dissection due to mammary cancer + (3x5 tablets of Wobenzym daily for 6.5 weeks + all patients: 2x daily CDT (combined decongestive therapy) for the first 20 days, consisting of manual lymphatic drainage (neck, arm, thorax), bandaging of the arm, specially tailored exercises and skin care)