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List of results

Hoopfer et al. (2015): Three-arm randomized phase III trial: Quality aloe and placebo cream versus powder as skin treatment during breast cancer radiation therapy + (Apply approx. 2.5 ml of placebo cream 3 times a day to irradiated skin during radiotherapy and for one month afterwards.)
Olsen et al. (2001): The effect of aloe vera gel/mild soap versus mild soap alone in preventing skin reactions in patients undergoing radiation therapy + (Apply the 100% aloe vera gel to the irradi … Apply the 100% aloe vera gel to the irradiated skin up 6 to 8 times a day after radiotherapy from the start of radiotherapy until the end of therpy+ all patients: advised to gently clean the irradiated skin with mild, unscented soap and dry it with a soft, clean towel, protect the skin from injury, avoid prolonged exposure to sunlight and wear loose-fitting clothing. sunlight and wear loose-fitting clothing.)
Cohen et al. (2018): Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial + (Approximately 5% of energy from carbohydra … Approximately 5% of energy from carbohydrate (≤20 g/day), 25% from protein (≤100 g/day) and 70% from fat (≥125 g/day)+ all participants received individual dietary advice from certified dieticians, weekly e-mails, and one-time personal meeting after baseline surveyime personal meeting after baseline survey)
Wyatt et al. (2017): A Randomized Clinical Trial of Caregiver-Delivered Reflexology for Symptom Management During Breast Cancer Treatment + (Attention by study partners (duration: NI, 1x week, 4 weeks in total))
Hejazi et al. (2013): A pilot clinical trial of radioprotective effects of curcumin supplementation in patients with prostate cancer + (BCM95, Biocurcumin (each capsule contained … BCM95, Biocurcumin (each capsule contained 440mg curcuminoids (347mg curcumin, 84mg desmethoxycurcumin, and 9mg bisdesmethoxycurcumin) and essential oil of turmeric 38mg)Orally, 2 capsules 3 times a dayStart: week -1 radiotherapyDuration: until the end of radiotherapy, approx. 9 weeks in total of radiotherapy, approx. 9 weeks in total)
Hejazi et al. (2016): Effect of Curcumin Supplementation During Radiotherapy on Oxidative Status of Patients with Prostate Cancer: A Double Blinded, Randomized, Placebo-Controlled Study + (BCM95, Biocurcumin (each capsule contained … BCM95, Biocurcumin (each capsule contained 440mg curcuminoids (347mg curcumin, 84mg desmethoxycurcumin, and 9mg bisdesmethoxycurcumin) and essential oil of turmeric 38mg)Orally, 2 capsules 3 times a dayStart: week -1 radiotherapyDuration: until the end of radiotherapy, approx. 9 weeks in total of radiotherapy, approx. 9 weeks in total)
Rastelli et al. (2011): Vitamin D and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial + (Baseline 25OHD levels between 20 and 29 ng … Baseline 25OHD levels between 20 and 29 ng/ml got a placebo, orally once a week for a total of eight consecutive weeks, and then once a month for the rest of the study;Baseline 25OHD levels between 10 and 19 ng/ml received a matching placebo orally for 16 consecutive weeks and then once a month for the rest of the studyhen once a month for the rest of the study)
Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study + (Baseline vitamin D deficiency level: <1 … Baseline vitamin D deficiency level: <10 ng/ml 100 000 IU vitamin D3 on day 1, 15, 28, 43, 58 and at 3 months,Baseline vitamin D deficiency level: 10-20 ng/ml 100 000 IU vitamin D3 on day 1, 15, 28, 43 and at 3 months, Baseline vitamin D deficiency level: 20-30 ng/ml 100 000 IU vitamin D3 on day 1, 15 and at 3 months00 IU vitamin D3 on day 1, 15 and at 3 months)
Margalit et al. (2012): Beta-carotene Antioxidant Use During Radiation Therapy and Prostate Cancer Outcome in the Physicians’ Health Study + (Beta-carotene 50mg orally every 2nd day, start at the time of radiation therapy, mean (range) follow-up: 10.5 years (0.3-27.2))
Stauder et al. (1991): Strahlentherapeutische Nebenwirkungen bei Abdominalkrebspatienten und deren Reduktion durch hydrolytische Enzyme + (Between 5 and 15 tablets of WOBE-MUGOS daily for 5 weeks: first two weeks average daily dose 10.6 (4.0), day 14 to day 35 averge daily dose 10.3(4.0) + all participants: radiation)
Nasser et al. (2017): Vitamin D ointment for prevention of radiation dermatitis in breast cancer patients + (Calcipotriol to the lateral side of the breast, Duration: while radiotherapy treatment)
Nasser et al. (2017): Vitamin D ointment for prevention of radiation dermatitis in breast cancer patients + (Calcipotriol to the medial side of the breast, Duration: while radiotherapy treatment)
Zalat et al. (2020): Evaluation of the cardioprotective effects of l-carnitine and silymarin in cancer patients receiving anthracycline-containing chemotherapy + (Capsules 3g one day before the chemotherapy cycle and 1 g/day for the following 21 days)
Moslemi et al. (2014): Oral zinc sulphate and prevention of radiation-induced oropharyngealmucositis in patients with head and neck cancers: A double blind, randomized controlled clinical trial + (Capsules filled with starch and designed s … Capsules filled with starch and designed same medicine firm, form and color to zinc sulphate, three times daily at 8 hours interval,Duration of intervention: started 10 days before beginning of treatment and continued to 8 weeks after the end of treatmentnued to 8 weeks after the end of treatment)
Najafizade et al. (2013): Preventive effects of zinc sulfate on taste alterations in patients under irradiation for head and neck cancers: A randomized placebo-controlled trial + (Capsules three times a day, after meals, Duration of intervention: started with beginning of radiotherapy and continued one month after completion of irradiation)
Dias et al. (2015): The chemopreventive effect of Ginkgo biloba extract 761 against cisplatin ototoxicity: a pilot study + (Capsules, 120 mg 2x/day Duration: throughout cisplatin therapy according to the respective protocol for the tumor (cumulative doses ranged from 50 to 300mg/m2).)
Dias et al. (2015): The chemopreventive effect of Ginkgo biloba extract 761 against cisplatin ototoxicity: a pilot study + (Capsules, 120 mg 2x/day Duration: throughout cisplatin therapy according to the respective protocol for the tumor (cumulative doses ranged from 50 to 300mg/m2).)
Lyckholm et al. (2012): A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders + (Capsules, containing lactose monohydrate powder and looked identical to the zinc capsules)
Uysal et al. (2016): Effects of foot massage applied in two different methods on symptom control in colorectal cancer patients: Randomised control trial + (Chemoradiantherapy, no information about duration in days)
Antunac et al. (2018): Vitamin D Supplementation and Survival in Metastatic Colorectal Cancer + (Cholecalciferol 2000 IU daily, for 2 years or until death, whichever came first)
Mansourian et al. (2015): The effect of "curcuma Longa" topical gel on radiation -induced oral mucositis in patients with head and neck cancer + (Coat entire mouth with gel 3 times a day Start: day 0 radiotherapy Duration: entire radiotherapy (21 days))
Tan et al. (2018): Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor + (Cold-hot compress for two days after surgery + all patients: surgery: third molar extraction was performed under local anesthesia)
Jatoi et al. (2002): Dronabinol Versus Megestrol Acetate Versus Combination Therapy for Cancer-Associated Anorexia: A North Central Cancer Treatment Group Study + (Combination of Megestrol Acetate (oral, 800mg/day liquid) and Dronabinol (oral, 2.5mg 2 times a day))
Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects + (Control arm patients did not receive any additional treatment + all patients received 50-60 Gy of external beam radiation in 20-30 fractions for 35(+/-1) days, followed by intra-cavitary rachytherapy at a dose of 20–30 Gy using a BARC applicator.)
Rao et al. (2014): The Indian Spice Turmeric Delays and Mitigates Radiation-Induced Oral Mucositis in Patients Undergoing Treatment for Head and Neck Cancer: An Investigational Study + (Curcumin solution; 1 capsule with 400g curcumin powder dissolved in approximately 80ml water (prepared by the nurse), 10ml as a mouthwash (4 times for 2 minutes each) Start: Day 1 radiotherapy, 6 times daily Duration: 7 weeks)
Beer et al. (2007): Double-blinded randomized study of high-dose calcitriol plus docetaxel compared with placebo plus docetaxel in androgen-independent prostate cancer: a report from the ASCENT Investigators + (DN-101 (45 μg) orally (high concentration formulation of calcitriol), weekly for 3 consecutive weeks of a 4-week cycle)

Kraft et al. (2012): L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial + (Daily Duration: 12 weeks)
Fallahi et al. (2013): Does vitamin E protect salivary glands from I-131 radiation damage in patients with thyroid cancer? + (Daily Start: Week -1 radioiodine therapy to 4 weeks after Duration: 5 weeks)
Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study + (Daily 400 IU vitamin D3)
Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects + (Daily 4x3 tablets of WOBE-MUGOS E (10mg pa … Daily 4x3 tablets of WOBE-MUGOS E (10mg papain, 40mg trypsin, 40mg chymotrypsin), starting 8(+/-1) days before the first radiotherapy session over a period of 69(+/-15) days.+ all patients received 50-60 Gy of external beam radiation in 20-30 fractions for 35(+/-6) days , followed by intra-cavitary brachytherapy at a dose of 20–30 Gy using a BARC applicator. dose of 20–30 Gy using a BARC applicator.)
Shokri et al. (2017): Comparison of the Complications of Platinum-Based Adjuvant Chemotherapy With and Without Ginger in a Pilot Study on Ovarian Cancer Patients + (Daily dose 2x 1g ginger capsules for 6 cycles)
Shokri et al. (2017): Comparison of the Complications of Platinum-Based Adjuvant Chemotherapy With and Without Ginger in a Pilot Study on Ovarian Cancer Patients + (Daily dose 2x 1g placebo capsules for 6 cycles)
Ansari et al. (2016): Efficacy of Ginger in Control of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients Receiving Doxorubicin- Based Chemotherapy + (Daily dose 2x2 capsules, every 12h for 3 days over 3 cycles, start not specified)
Ansari et al. (2016): Efficacy of Ginger in Control of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients Receiving Doxorubicin- Based Chemotherapy + (Daily dose 2x2 ginger capsules (250mg ginger powder each), every 12h for 3 days over 3 cycles, start not specified)
Thamlikitkul et al. (2017): Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study + (Daily dose 2x500mg ginger capsule (dried ginger powder) for 5 days, starting 30min before second chemotherapy cycle; Antiemetics: Ondansetron + Dexamethason; Crossover in cycle 3)
Arslan et al. (2015): Oral Intake of Ginger for Chemotherapy-Induced Nausea and Vomiting Among Women With Breast Cancer + (Daily dose 2x500mg ginger powder with a spoonful of yogurt for 3 days, first dose 30min before start of Chemotherapy)
Panahi et al. (2012): Effect of Ginger on Acute and Delayed Chemotherapy-Induced Nausea and Vomiting: A Pilot, Randomized, Open-Label Clinical Trial + (Daily dose 3x0.5g Every 8h, starting 30min after chemotherapy)
Bossi et al. (2017): A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin + (Daily dose 4 Placebo capsule, i.e. 2 capsules in the morning and 2 capsules in the late afternoon, starting the day after chemotherapy for 42-56 days (depending on duration of chemotherapy))
Yekta et al. (2012): Ginger as a miracle against chemotherapy-induced vomiting + (Daily dose 4x250mg, every 6 hours for 6 days from three days before the start of Chemotherapy)
Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial + (Daily dose 4x300mg ginger capsules (standardized extract), with meals, per cycle for 5 days, starting on the day of chemotherapy over 3 cycles + Antiemetics (for 3 chemotherapy cycles, duration: day of chemo to 5 days post chemo))
Bossi et al. (2017): A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin + (Daily dose 4x40mg ginger capsule (“Ginger CO2 supercritical extract”), i.e. 2 capsules in the morning and 2 capsules in the late afternoon, starting the day after chemotherapy for 42-56 days (depending on duration of chemotherapy))
Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study + (Daily dose 4x500mg before meals and one in … Daily dose 4x500mg before meals and one in the evening from day 1 to day 5 of chemotherapy+ standard antiemetic medication included 20 mg of dexamethasone, 8 mg of ondansetron, and 50 mg of ranitidine which were injected 30 min before chemotherapy administration; if necessary 50mg dimenhydrinate before chemotherapy and 5 days at homeate before chemotherapy and 5 days at home)
Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study + (Daily dose before meals and one in the eve … Daily dose before meals and one in the evening from day 1 to day 5 of chemotherapy + standard antiemetic medication included 20 mg of dexamethasone, 8 mg of ondansetron, and 50 mg of ranitidine which were injected 30 min before chemotherapy administration; if necessary 50mg dimenhydrinate before chemotherapy and 5 days at homeate before chemotherapy and 5 days at home)
Sanaati et al. (2016): Effect of Ginger and Chamomile on Nausea and Vomiting Caused by Chemotherapy in Iranian Women with Breast Cancer + (Daily dose of 2x500mg chamomile capsules (not standardized), from 5 days before chemotherapy until 5 days after chemotherapy)
Sanaati et al. (2016): Effect of Ginger and Chamomile on Nausea and Vomiting Caused by Chemotherapy in Iranian Women with Breast Cancer + (Daily dose of 2x500mg ginger capsules (not standardized), from 5 days before chemotherapy until 5 days after chemotherapy)
Shooriabi et al. (2016): The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: A double-blind controlled study + (Daily dose, 4x500mg capsules, every 6 hours, for 2 weeks)
Shooriabi et al. (2016): The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: A double-blind controlled study + (Daily dose, 4x500mg ginger capsules, every 6 hours, for 2 weeks)
Da Costa et al. (2009): Effectiveness of Guarana (Paullinia cupana) for Postradiation Fatigue and Depression Results of a Pilot Double-Blind Randomized Study + (Daily for 14 days Cross-over: 14 days of placebo)
Da Costa et al. (2009): Effectiveness of Guarana (Paullinia cupana) for Postradiation Fatigue and Depression Results of a Pilot Double-Blind Randomized Study + (Daily for 14 days Cross-over: 75 mg of guayana extract daily for 14 days)
Yap et al. (2017): Predictors of hand-foot syndrome and pyridoxine for prevention of capecitabine-induced hand-foot syndrome: a randomized clinical trial + (Daily for maximum 8 of cycles of 3 weeks each, from start of chemotherapy)