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List of results

Rao et al. (2014): The Indian Spice Turmeric Delays and Mitigates Radiation-Induced Oral Mucositis in Patients Undergoing Treatment for Head and Neck Cancer: An Investigational Study + (Curcumin solution; 1 capsule with 400g curcumin powder dissolved in approximately 80ml water (prepared by the nurse), 10ml as a mouthwash (4 times for 2 minutes each) Start: Day 1 radiotherapy, 6 times daily Duration: 7 weeks)
Beer et al. (2007): Double-blinded randomized study of high-dose calcitriol plus docetaxel compared with placebo plus docetaxel in androgen-independent prostate cancer: a report from the ASCENT Investigators + (DN-101 (45 μg) orally (high concentration formulation of calcitriol), weekly for 3 consecutive weeks of a 4-week cycle)
Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597 + (Daily)
Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer + (Daily)
Kraft et al. (2012): L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial + (Daily Duration: 12 weeks)
Fallahi et al. (2013): Does vitamin E protect salivary glands from I-131 radiation damage in patients with thyroid cancer? + (Daily Start: Week -1 radioiodine therapy to 4 weeks after Duration: 5 weeks)
Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study + (Daily 400 IU vitamin D3)
Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects + (Daily 4x3 tablets of WOBE-MUGOS E (10mg pa … Daily 4x3 tablets of WOBE-MUGOS E (10mg papain, 40mg trypsin, 40mg chymotrypsin), starting 8(+/-1) days before the first radiotherapy session over a period of 69(+/-15) days.+ all patients received 50-60 Gy of external beam radiation in 20-30 fractions for 35(+/-6) days , followed by intra-cavitary brachytherapy at a dose of 20–30 Gy using a BARC applicator. dose of 20–30 Gy using a BARC applicator.)
Shokri et al. (2017): Comparison of the Complications of Platinum-Based Adjuvant Chemotherapy With and Without Ginger in a Pilot Study on Ovarian Cancer Patients + (Daily dose 2x 1g ginger capsules for 6 cycles)
Shokri et al. (2017): Comparison of the Complications of Platinum-Based Adjuvant Chemotherapy With and Without Ginger in a Pilot Study on Ovarian Cancer Patients + (Daily dose 2x 1g placebo capsules for 6 cycles)
Ansari et al. (2016): Efficacy of Ginger in Control of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients Receiving Doxorubicin- Based Chemotherapy + (Daily dose 2x2 capsules, every 12h for 3 days over 3 cycles, start not specified)
Ansari et al. (2016): Efficacy of Ginger in Control of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients Receiving Doxorubicin- Based Chemotherapy + (Daily dose 2x2 ginger capsules (250mg ginger powder each), every 12h for 3 days over 3 cycles, start not specified)
Thamlikitkul et al. (2017): Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study + (Daily dose 2x500mg ginger capsule (dried ginger powder) for 5 days, starting 30min before second chemotherapy cycle; Antiemetics: Ondansetron + Dexamethason; Crossover in cycle 3)
Arslan et al. (2015): Oral Intake of Ginger for Chemotherapy-Induced Nausea and Vomiting Among Women With Breast Cancer + (Daily dose 2x500mg ginger powder with a spoonful of yogurt for 3 days, first dose 30min before start of Chemotherapy)
Panahi et al. (2012): Effect of Ginger on Acute and Delayed Chemotherapy-Induced Nausea and Vomiting: A Pilot, Randomized, Open-Label Clinical Trial + (Daily dose 3x0.5g Every 8h, starting 30min after chemotherapy)
Bossi et al. (2017): A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin + (Daily dose 4 Placebo capsule, i.e. 2 capsules in the morning and 2 capsules in the late afternoon, starting the day after chemotherapy for 42-56 days (depending on duration of chemotherapy))
Yekta et al. (2012): Ginger as a miracle against chemotherapy-induced vomiting + (Daily dose 4x250mg, every 6 hours for 6 days from three days before the start of Chemotherapy)
Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial + (Daily dose 4x300mg ginger capsules (standardized extract), with meals, per cycle for 5 days, starting on the day of chemotherapy over 3 cycles + Antiemetics (for 3 chemotherapy cycles, duration: day of chemo to 5 days post chemo))
Bossi et al. (2017): A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin + (Daily dose 4x40mg ginger capsule (“Ginger CO2 supercritical extract”), i.e. 2 capsules in the morning and 2 capsules in the late afternoon, starting the day after chemotherapy for 42-56 days (depending on duration of chemotherapy))
Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study + (Daily dose 4x500mg before meals and one in … Daily dose 4x500mg before meals and one in the evening from day 1 to day 5 of chemotherapy+ standard antiemetic medication included 20 mg of dexamethasone, 8 mg of ondansetron, and 50 mg of ranitidine which were injected 30 min before chemotherapy administration; if necessary 50mg dimenhydrinate before chemotherapy and 5 days at homeate before chemotherapy and 5 days at home)
Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study + (Daily dose before meals and one in the eve … Daily dose before meals and one in the evening from day 1 to day 5 of chemotherapy + standard antiemetic medication included 20 mg of dexamethasone, 8 mg of ondansetron, and 50 mg of ranitidine which were injected 30 min before chemotherapy administration; if necessary 50mg dimenhydrinate before chemotherapy and 5 days at homeate before chemotherapy and 5 days at home)
Sanaati et al. (2016): Effect of Ginger and Chamomile on Nausea and Vomiting Caused by Chemotherapy in Iranian Women with Breast Cancer + (Daily dose of 2x500mg chamomile capsules (not standardized), from 5 days before chemotherapy until 5 days after chemotherapy)
Sanaati et al. (2016): Effect of Ginger and Chamomile on Nausea and Vomiting Caused by Chemotherapy in Iranian Women with Breast Cancer + (Daily dose of 2x500mg ginger capsules (not standardized), from 5 days before chemotherapy until 5 days after chemotherapy)
Shooriabi et al. (2016): The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: A double-blind controlled study + (Daily dose, 4x500mg capsules, every 6 hours, for 2 weeks)
Shooriabi et al. (2016): The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: A double-blind controlled study + (Daily dose, 4x500mg ginger capsules, every 6 hours, for 2 weeks)

Da Costa et al. (2009): Effectiveness of Guarana (Paullinia cupana) for Postradiation Fatigue and Depression Results of a Pilot Double-Blind Randomized Study + (Daily for 14 days Cross-over: 14 days of placebo)

Da Costa et al. (2009): Effectiveness of Guarana (Paullinia cupana) for Postradiation Fatigue and Depression Results of a Pilot Double-Blind Randomized Study + (Daily for 14 days Cross-over: 75 mg of guayana extract daily for 14 days)
Yap et al. (2017): Predictors of hand-foot syndrome and pyridoxine for prevention of capecitabine-induced hand-foot syndrome: a randomized clinical trial + (Daily for maximum 8 of cycles of 3 weeks each, from start of chemotherapy)
Paur et al. (2017): Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA + (Daily from 3 weeks before radiotherapy/surgery until radiotherapy/surgery)
Rastelli et al. (2011): Vitamin D and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial + (Daily supplementation with 1,000 mg of cal … Daily supplementation with 1,000 mg of calcium carbonate and 400 IU of Vitamin D3:Baseline 25OHD levels between 20 and 29 ng/ml were randomized to receive vitamin D2, one 50,000 IU capsule, orally once a week for a total of eight consecutive weeks, and then once a month for the rest of the study;Baseline 25OHD levels between 10 and 19 ng/ml received Vitamin D2 50,000 IU capsule or a matching placebo orally for 16 consecutive weeks and then once a month for the rest of the studyhen once a month for the rest of the study)
Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy + (Day 0 chemotherapy: 250 mg 1x daily Duration: 7 days in each chemotherapy cycle)
Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy + (Day 0 of chemotherapy: 400 mg 1x daily Duration: until 1 month after the end of chemotherapy)
Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy + (Day 2 chemotherapy: 10 mg 3x daily Duration: Day 2 to Day 5 in each chemotherapy cycle)
Stendell-Hollis et al. (2010): Green tea improves metabolic biomarkers, not weight or body composition: a pilot study in overweight breast cancer survivors + (Decaffeinated green tea product provided b … Decaffeinated green tea product provided by Unilever, Lipton; 960ml daily (=4 tea bags, inclusive 128.84mg EGCG); tea bags were placed in the provided tea mug and 240 mL of boiling water was added and allowed to steep for a period of 3 minutes+ all participants: required to successfully complete a 2 week run-in period consisting of daily intake of 960 mL of herbal teang of daily intake of 960 mL of herbal tea)
Lian et al. (2014): Comparing the Effectiveness of Green Tea versus Topical Metronidazole Powder in Malodorous Control of Fungating Malignant Wounds in a Controlled Randomised Study + (Dressing Procedure 1. Irrigate wound with … Dressing Procedure1. Irrigate wound with green tea solution with 20ml syringe until return flow is clear2. Cover wound with absorbent pad(s) with dry green tea bag (insert within the absorbent pad) and secure with 2-inch micropore tape+ Assigned nurse performs for all participantsDay 1 and day 7: wound assessment; questionnaire on quality of life; photography of woundDay 1 to day 7: daily dressing; daily odour rating using VNS by patient and nurse independentlying VNS by patient and nurse independently)
Lian et al. (2014): Comparing the Effectiveness of Green Tea versus Topical Metronidazole Powder in Malodorous Control of Fungating Malignant Wounds in a Controlled Randomised Study + (Dressing Procedure Irrigate wound with Nor … Dressing ProcedureIrrigate wound with Normal Saline 0.9% with 20ml syringe until return flow is clear1. Sprinkle metronidazole powder to wound bed (pound metronidazole tablet(s) finely)2. Cover wound with absorbent pad(s) and secure with 2-inch micropore tape+ Assigned nurse performs for all participants:Day 1 and day 7: wound assessment; questionnaire on quality of life; photography of woundDay 1 to day 7: daily dressing; daily odour rating using VNS by patient and nurse independentlying VNS by patient and nurse independently)
Cavallini et al. (2005): Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy + (Duration: 4 month)
Özdelikara et al. (2017): The effect of reflexology on the quality of life with breast cancer patients + (Each session started on the right foot and … Each session started on the right foot and continued on the left one. Primary relaxation techniques were performed on both feet, then, reflexology techniques were performed on all system organs.From 2nd-4th chemotherapy cycle, during chemotherapy, duration: 30-40mine, during chemotherapy, duration: 30-40min)
Panahi et al. (2012): Effect of Ginger on Acute and Delayed Chemotherapy-Induced Nausea and Vomiting: A Pilot, Randomized, Open-Label Clinical Trial + (Every 8h, starting 30min after Chemotherapy)
Marucci et al. (2017): Double-blind randomized phase III study comparing a mixture of natural agents versus placebo in the prevention of acute mucositis during chemoradiotherapy for head and neck cancer + (Faringel Herbal mouthwash (propolis, aloe, … Faringel Herbal mouthwash (propolis, aloe, calendula, camomile)Rinse with 7mL of mouthwash 4 times per day (before each main meal and radiotherapy session) during weekdays, and 3 times per day (before each main meal) during weekend+all patients: concomitant chemoradiotherapy (daily treatment, 5 times per week, for 6-6.5 weeks)+ dental and nutritional evaluation before treatmentnd nutritional evaluation before treatment)
Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies + (First week mean number of sprays 3.7, stabilized over 4 weeks (7.4 sprays per day))
Fahimi et al. (2011): Evaluating the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens + (Four capsules of placebo (lactose))
Fahimi et al. (2011): Evaluating the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens + (Four capsules of powdered ginger (Zintoma®, Gol Daru) daily (each capsule contained 250 mg of ginger))
Iovino et al. (2018): High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ naive lymphocytes and prevents TTV reactivation + (From day +5 post-transplant)
Afonseca et al. (2013): Vitamin E for prevention of oxaliplatin-induced peripheral neuropathy: A pilot randomized clinical trial + (From day 0 chemotherapy 400mg daily until end of chemotherapy)
Afonseca et al. (2013): Vitamin E for prevention of oxaliplatin-induced peripheral neuropathy: A pilot randomized clinical trial + (From day 0 chemotherapy daily until end of chemotherapy)
Puri et al. (2010): Lycopene in treatment of high-grade gliomas: A pilot study + (From day 1 of radiotherapy for 6 weeks)
Özdelikara et al. (2017): The Effect of Reflexology on Chemotherapy-induced Nausea, Vomiting, and Fatigue in Breast Cancer Patients + (From the 2nd-4th chemotherapy cycle, during chemotherapy duration: 30-40min)
Stendell-Hollis et al. (2010): Green tea improves metabolic biomarkers, not weight or body composition: a pilot study in overweight breast cancer survivors + (Herbal tea product provided by Unilever, L … Herbal tea product provided by Unilever, Lipton; 960ml daily (=4 tea bags, without EGCG); tea bags were placed in the provided tea mug and 240 mL of boiling water was added and allowed to steep for a period of 3 minutes+ all participants: required to successfully complete a 2-week run-in period consisting of daily intake of 960 mL of herbal teang of daily intake of 960 mL of herbal tea)
Cohen et al. (2018): Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial + (High fiber, low fat every day + all participants received individual dietary advice from certified dieticians, weekly e-mails, and one-time personal meeting after baseline survey)
Bairati et al. (2005): Randomized Trial of Antioxidant Vitamins to Prevent Acute Adverse Effects of Radiation Therapy in Head and Neck Cancer Patients + (In 1996 (2 years after the start of the st … In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported.'''OLD''' (n=79)- 30mg Betacarotin + 400 IU Vitamin E daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days'''NEW''' (n=194)- 400 IU Vitamin E daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapyDuration: up to 3 years after radiotherapy)