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List of results

Marucci et al. (2017): Double-blind randomized phase III study comparing a mixture of natural agents versus placebo in the prevention of acute mucositis during chemoradiotherapy for head and neck cancer + (Faringel Herbal mouthwash (propolis, aloe, … Faringel Herbal mouthwash (propolis, aloe, calendula, camomile)Rinse with 7mL of mouthwash 4 times per day (before each main meal and radiotherapy session) during weekdays, and 3 times per day (before each main meal) during weekend+all patients: concomitant chemoradiotherapy (daily treatment, 5 times per week, for 6-6.5 weeks)+ dental and nutritional evaluation before treatmentnd nutritional evaluation before treatment)
Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies + (First week mean number of sprays 3.7, stabilized over 4 weeks (7.4 sprays per day))
Fahimi et al. (2011): Evaluating the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens + (Four capsules of placebo (lactose))
Fahimi et al. (2011): Evaluating the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens + (Four capsules of powdered ginger (Zintoma®, Gol Daru) daily (each capsule contained 250 mg of ginger))
Iovino et al. (2018): High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ naive lymphocytes and prevents TTV reactivation + (From day +5 post-transplant)
Afonseca et al. (2013): Vitamin E for prevention of oxaliplatin-induced peripheral neuropathy: A pilot randomized clinical trial + (From day 0 chemotherapy 400mg daily until end of chemotherapy)
Afonseca et al. (2013): Vitamin E for prevention of oxaliplatin-induced peripheral neuropathy: A pilot randomized clinical trial + (From day 0 chemotherapy daily until end of chemotherapy)
Puri et al. (2010): Lycopene in treatment of high-grade gliomas: A pilot study + (From day 1 of radiotherapy for 6 weeks)
Özdelikara et al. (2017): The Effect of Reflexology on Chemotherapy-induced Nausea, Vomiting, and Fatigue in Breast Cancer Patients + (From the 2nd-4th chemotherapy cycle, during chemotherapy duration: 30-40min)
Stendell-Hollis et al. (2010): Green tea improves metabolic biomarkers, not weight or body composition: a pilot study in overweight breast cancer survivors + (Herbal tea product provided by Unilever, L … Herbal tea product provided by Unilever, Lipton; 960ml daily (=4 tea bags, without EGCG); tea bags were placed in the provided tea mug and 240 mL of boiling water was added and allowed to steep for a period of 3 minutes+ all participants: required to successfully complete a 2-week run-in period consisting of daily intake of 960 mL of herbal teang of daily intake of 960 mL of herbal tea)
Cohen et al. (2018): Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial + (High fiber, low fat every day + all participants received individual dietary advice from certified dieticians, weekly e-mails, and one-time personal meeting after baseline survey)
Bairati et al. (2005): Randomized Trial of Antioxidant Vitamins to Prevent Acute Adverse Effects of Radiation Therapy in Head and Neck Cancer Patients + (In 1996 (2 years after the start of the st … In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported.'''OLD''' (n=79)- 30mg Betacarotin + 400 IU Vitamin E daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days'''NEW''' (n=194)- 400 IU Vitamin E daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapyDuration: up to 3 years after radiotherapy)
Bairati et al. (2006): Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients + (In 1996 (2 years after the start of the st … In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported.'''OLD''' (n=79)- 30mg Betacarotin + 400 IU Vitamin E daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days'''NEW''' (n=194)- 400 IU Vitamin E daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapyDuration: up to 3 years after radiotherapy)
Bairati et al. (2005): A Randomized Trial of Antioxidant Vitamins to Prevent Second Primary Cancers in Head and Neck Cancer Patients + (In 1996 (2 years after the start of the st … In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported.'''OLD''' (n=79)- 30mg Betacarotin + 400 IU Vitamin E daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days'''NEW''' (n=194)- 400 IU Vitamin E daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapyDuration: up to 3 years after radiotherapy)
Bairati et al. (2005): Randomized Trial of Antioxidant Vitamins to Prevent Acute Adverse Effects of Radiation Therapy in Head and Neck Cancer Patients + (In 1996 (2 years after the start of the st … In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported.'''OLD''' (n=77)- 1 placebo daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days'''NEW''' (n=190)- 2 placebos daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapyDuration: up to 3 years after radiotherapy)
Bairati et al. (2006): Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients + (In 1996 (2 years after the start of the st … In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported.'''OLD''' (n=77)- 1 placebo daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days'''NEW''' (n=190)- 2 placebos daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapyDuration: up to 3 years after radiotherapy)
Bairati et al. (2005): A Randomized Trial of Antioxidant Vitamins to Prevent Second Primary Cancers in Head and Neck Cancer Patients + (In 1996 (2 years after the start of the st … In 1996 (2 years after the start of the study) the beta-carotene intervention was discontinued due to indications of harmful effects. Therefore 2 types of "Dosage and regime" (old, i.e. before 1996 and new, i.e. after 1996) are reported.'''OLD''' (n=77)- 1 placebo daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapy, median (range): 320 (21-609) days'''NEW''' (n=190)- 2 placebos daily, start with first day of radiotherapy- Duration: up to 3 years after radiotherapyDuration: up to 3 years after radiotherapy)
Zalat et al. (2020): Evaluation of the cardioprotective effects of l-carnitine and silymarin in cancer patients receiving anthracycline-containing chemotherapy + (In capsules 140 mg daily during the chemotherapy cycle.)
Sharp et al. (2010): A randomised, controlled trial of the psychological effects of reflexology in early breast cancer + (Intervention 3: SIS (comparator intervention – treatment asusual). 7 weeks post surgery to 15 weeks post surgery)
Hajimohammadebrahim-Ketabforoush et al. (2019): Effect of Vitamin D Supplementation on Postcraniotomy Pain After Brain Tumor Surgery: A Randomized Clinical Trial + (Intramuscular injection of 300,000 IU vita … Intramuscular injection of 300,000 IU vitamin D 2-14 days (with an average of 5 days) before surgery+ all participants: pain medication, including intravenous injection of apotel 1 g, morphine sulfate 3 mg, and oral acet-aminophen 500 mg, depending on each patient’s need in the intensive care unit and wards need in the intensive care unit and ward)
Jeon et al. (2016): Effect of intravenous high dose Vitamin C on postoperative pain and morphine use after laparoscopic colectomy: A randomized controlled trial + (Intravenous, 30 minutes)
Cruciani et al. (2012): L-Carnitine Supplementation for the Management of Fatigue in Patients With Cancer: An Eastern Cooperative Oncology Group Phase III, Randomized, Double-Blind, Placebo-Controlled Trial + (L-carnitine was a standardized commercial preparation of 10 g of levocarnitine inert salt in 100-mL solution 2g (2x 1g) daily oral Duration: 8 weeks)
Sun et al. (2016): A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy + (Lactose, 3 x 1000 mg Duration: 8 weeks)
Freedland et al. (2020): A Randomized Controlled Trial of a 6-month low carbohydrate intervention on disease progression in men with recurrent prostate cancer: Carbohydrate and Prostate Study 2 (CAPS2) + (Low-carbohydrate diet with ≤20g carbohydrates per day Supervision by dietician by telephone weekly in the first 3 months and then every 2 weeks in the last 3 months)
Mahmoodnia et al. (2017): Ameliorative effect of lycopene effect on cisplatin-induced nephropathy in patients + (Lycopene tablet (25 mg) each 12 hours from 24 hours before to 72 hours after chemotherapy (cisplatin administration))

Grimison et al. (2020): Oral THC:CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting: a randomised, placebo-controlled, phase II crossover trial + (Median (SD) number of capsules = 3 (2-4))