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- Ertekin et al. (2004): Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized study + (Three times daily at 8-hour intervals, emp … Three times daily at 8-hour intervals, empty capsules bought from the same medicine firm to be identical to the zinc sulfate capsules,</br>Duration was from first day of radiotherapy, during radiotherapy and for 6 weeks after treatment (including weekends and other times when interruption of radiotherapy was necessary)nterruption of radiotherapy was necessary))