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List of results

Zalat et al. (2020): Evaluation of the cardioprotective effects of l-carnitine and silymarin in cancer patients receiving anthracycline-containing chemotherapy + (Bad compliance to protocol)
Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (Baseline: 1 - Began coumadin, 1 - Gastroin … Baseline:1 - Began coumadin, 1 - Gastrointestinal, 1 - Low platelets, 1 - Treatment change, 1 - Other medical, 6 - Changed mind, 5 - Incomplete forms, 1 - IneligibleStudy Cycle 2: 2 - Chemotoxicity, 9 - Gastrointestinal, 1 - Low platelets, 5 - Off chemotherapy, 7 - Treatment change, 1 - Treatment delay, 5 - Other medical, 13 - Changed mind, 1 - Lost medication, 5 - Incomplete forms 1 - Lost medication, 5 - Incomplete forms)
Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (Baseline: 1 - Began coumadin, 2 - Chemoto … Baseline: 1 - Began coumadin, 2 - Chemotoxicity, 2 - Gastrointestinal, 1 - Low platelets, 3 - Off chemotherapy, 1 - Treatment delay, 1 - Other medical, 5 - Changed mind, 2 - Incomplete formsStudy Cycle 2: 1 - Bleeding, 5 - Chemotoxicity, 7 - Gastrointestinal, 3 - Low platelets, 5 - Off chemotherapy, 3 - Treatment change, 5 - Treatment delay, 1 - Low WBC, 5 - Other medical, 10 - Changed mind, 4 - Incomplete forms, 1 - Deceasedd mind, 4 - Incomplete forms, 1 - Deceased)
Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (Baseline: 1 - Began coumadin, 2 - Chemoto … Baseline: 1 - Began coumadin, 2 - Chemotoxicity, 2 - Gastrointestinal, 1 - Off chemotherapy, 5 - Other medical, 11- Changed mind, 3 - Incomplete formsStudy Cycle 2: 3 - Chemotoxicity, 5 - Gastrointestinal, 1 - Low platelets, 3 - Off chemotherapy, 1 - Radiation therapy, 1 - Treatment change, 2 - Treatment delay, 1 - Disease progression, 5 - Other medical, 15 - Changed mind, 1 - Drug incorrectly given, 1 - Lost medication, 10 -Incomplete forms 1 - Lost medication, 10 -Incomplete forms)
Ryan et al. (2011): Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients + (Baseline: 1 - Bleeding, 1 - Chemotoxicity … Baseline: 1 - Bleeding, 1 - Chemotoxicity, 1 - Gastrointestinal, 3 - Off chemotherapy, 2 - Other medical, 14 - Changed mind, 1 - Incomplete formsStudy Cycle 2: 1 - Bleeding, 4 - Chemotoxicity, 5 - Gastrointestinal, 2 - Low platelets, 2 - Off chemotherapy, 5 - Treatment change, 1 - Treatment delay, 1- Disease progression, 7 - Other medical, 7 - Changed mind, 2 - Drug incorrectly given, 6 - Incomplete formsug incorrectly given, 6 - Incomplete forms)
Kottschade et al. (2011): The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase 3 clinical trial + (Before randomization: n=4 cancelled, n=3 ineligible During study: n=11 refused further treatment, n=8 adverse events, n=2 alternate treatment, n=2 other medical problems, n=6 other reasons)
Kottschade et al. (2011): The use of vitamin E for the prevention of chemotherapy-induced peripheral neuropathy: results of a randomized phase 3 clinical trial + (Before randomization: n=7 cancelled, n=4 ineligible During study: n=18 refused further treatment, n=3 adverse events, n=4 alternate treatment, n=4 other medical problems, n=3 other reasons, n=1 died on study)
Konmun et al. (2017): A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy + (Before treatment: - consent withdrawn (n=2) - referred for treatment at another hospital (n=1) - inability to swallow a capsule (n=1) After treatment (but excluded from analysis): - protocol violation (n=1) - consent withdrawn (n=2))
Konmun et al. (2017): A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy + (Before treatment: - consent withdrawn (n=1) - referred for treatment at another hospital (n=1) After treatment (but excluded from analysis): - consent withdrawn (n=5))
Henning et al. (2015): Randomized Clinical Trial of Brewed Green and Black Tea in Men With Prostate Cancer Prior to Prostatectomy + (Caffeine reactions (n=2); surgery postponed (n=2); unrelated death (n=1); tea volume too large (n=3), stomach distress (n=1))
Kirste et al. (2011): Boswellia serrata Acts on Cerebral Edema in Patients Irradiated for Brain Tumors. A Prospective, Randomized, Placebo-Controlled, Double-Blind Pilot Trial + (Could not swallow capsules n = 1 Refused to swallow capsules n = 1)
Lyckholm et al. (2012): A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders + (Death (non–study related) (n=4), cancer treatment discontinued (n=4), toxicity (diarrhea, abdominal pain, cramps, diaphoresis) (n=2), pill burden (n=2), family member asked the patient to withdraw consent (n=1), and no reason given (n=2))
Lyckholm et al. (2012): A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders + (Death (non–study related) (n=4), cancer treatment discontinued (n=4), toxicity (diarrhea, abdominal pain, cramps, diaphoresis) (n=2), pill burden (n=2), family member asked the patient to withdraw consent (n=1), and no reason given (n=2))
Lian et al. (2014): Comparing the Effectiveness of Green Tea versus Topical Metronidazole Powder in Malodorous Control of Fungating Malignant Wounds in a Controlled Randomised Study + (Death due to advanced cancer on day 5)
Frankling et al. (2021): ‘Palliative-D’ - Vitamin D Supplementation to Palliative Cancer Patients: A Double Blind, Randomized Placebo-Controlled Multicenter Trial + (Death due to cancer)
Frankling et al. (2021): ‘Palliative-D’ - Vitamin D Supplementation to Palliative Cancer Patients: A Double Blind, Randomized Placebo-Controlled Multicenter Trial + (Death due to cancer)
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia + (Death due to progression)
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia + (Death due to progression)
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia + (Death due to progression)
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia + (Death due to progression)
Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia + (Death due to progression)

Argyriou et al. (2006): Preventing Paclitaxel-Induced Peripheral neuropathy: A Phase 2 Trial of Vitamin E Supplementation + (Death n=1, Disease progression n=2)

Argyriou et al. (2006): A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results + (Death n=1, disease progression n=1)
Argyriou et al. (2006): A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results + (Death n=2, disease progression n=1)
Liu et al. (2010): Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial + (Did not complete salivary dosimetry measurements)
Liu et al. (2010): Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial + (Did not complete salivary dosimetry measurements)
Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study + (Did not receive allocated intervention (Withdrew from study, adverse event))
Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer + (Did not receive allocated intervention (no … Did not receive allocated intervention (not to accept contributing): n=1Lost to follow-up: discontinued tablets (n=1); discontinued radiation due to individual preferences: n=4Inconsistencies in the number of drop-outs in the selenium arm: flowchart reports analyzed n=33 from n=42, but only reports drop-out reasons for n=6 (reasons missing n=3); table of baseline characteristics reports data of n=37eline characteristics reports data of n=37)
Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer + (Did not receive allocated intervention (not to accept contributing): n=4 Lost to follow-up: discontinued radiation due to individual preferences: n=4)
Ferreira et al. (2004): Protective effect of alpha-tocopherol in head and neck cancer radiation-induced mucositis: A double-blind randomized trial + (Did not receive the prescribed doses: n=2 because of intense mucositis and n=1 because of death caused by tumor progression)
Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study + (Did not received allocated intervention (Withdrew from study, adverse event, other))
Sangthawan et al. (2013): A randomized double-blind, placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patients + (Died during the course of radiation)
Sontakke et al. (2003): Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: A randomized, cross-over, double blind study + (Died, n = 4 Refused to continue chemotherapy due to inadequate control of nausea and vomiting, n = 2)
Sontakke et al. (2003): Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: A randomized, cross-over, double blind study + (Died, n = 4 Refused to continue chemotherapy due to inadequate control if nausea and vomiting, n = 2 No reporting back for second cycle, n = 2)
Sontakke et al. (2003): Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: A randomized, cross-over, double blind study + (Died: n = 4, Drop out during second cycle despite adequate control: n = 2, No reporting back for second cycle, n = 2)
Yekta et al. (2012): Ginger as a miracle against chemotherapy-induced vomiting + (Discontinuation of Chemotherapy, lack of compliance or death)
Yekta et al. (2012): Ginger as a miracle against chemotherapy-induced vomiting + (Discontinuation of Chemotherapy, lack of compliance or death)
Grimison et al. (2020): Oral THC:CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting: a randomised, placebo-controlled, phase II crossover trial + (Discontinued after THC:CBD (n = 4): Death (n = 1); failure to comply (n = 1); chemotherapy stopped (n = 1); patient preference (n = 1))
Grimison et al. (2020): Oral THC:CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting: a randomised, placebo-controlled, phase II crossover trial + (Discontinued after placebo (n = 2): chemotherapy stopped (n = 1); patient preference (n = 1))
Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy + (Discontinued guarana: n = 2 - Palpitations … Discontinued guarana: n = 2- Palpitations: n = 1 - Patient discontinued medication due to herpes zoster: n = 1 Excluded for forgetting to take more than 1 pill: n = 5Note: Time of Drop-Outs unclear, since all patients are noted to start placebo but drop-out occured for guaranat placebo but drop-out occured for guarana)
Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy + (Discontinued placebo: n = 2, - Rash: n = 1, - Palpitations: n = 1 Excluded for forgetting to take more than 1 pill: n = 6 Note: Time of Drop-Outs unclear, since all patients are noted to start guarana but drop-out occured for placebo)
Argyriou et al. (2006): Preventing Paclitaxel-Induced Peripheral neuropathy: A Phase 2 Trial of Vitamin E Supplementation + (Disease progression n=1, patient decision n=1)
Vitale et al. (2020): ZeOxaNMulti Trial: A Randomized, Double-Blinded, Placebo-Controlled Trial of Oral PMA-Zeolite to Prevent Chemotherapy-Induced Side Effects, in Particular, Peripheral Neuropathy + (Disease progression, unacceptable toxicity, or the patient’s refusal to continue the treatment No number was given for the individual reasons of Drop-outs)
Vitale et al. (2020): ZeOxaNMulti Trial: A Randomized, Double-Blinded, Placebo-Controlled Trial of Oral PMA-Zeolite to Prevent Chemotherapy-Induced Side Effects, in Particular, Peripheral Neuropathy + (Disease progression, unacceptable toxicity, or the patient’s refusal to continue the treatment No number was given for the individual reasons of Drop-outs)
Paur et al. (2017): Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA + (Dropped out (n=1); acute unrelated illness (n=2))
Shapiro et al. (2016): Randomized, blinded trial of vitamin D3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS) + (Dropped out during run-in period)
Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial + (Due to side effects: n = 1, consent withdrawn: n = 5, difficulty swallowing capsule: n = 2, contact lost: n = 1)