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- Nguyen et al. (2012): Randomized, Double-Blind, Placebo-Controlled Trial of Polyphenon E in Prostate Cancer Patients before Prostatectomy: Evaluation of Potential Chemopreventive Activities + (Drank tea regularly within 1 month of enro … Drank tea regularly within 1 month of enrollment (more than 6 servings of hot tea or 12 servings of iced tea or equivalent combination per week); receiving other investigational agents; history of allergic reactions attributed to compounds of similar chemical to polyphenon E; uncontrolled intercurrent illnesshenon E; uncontrolled intercurrent illness)