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- Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies + (Male, n(%) per arm: Sativex = 106 (53.0) Placebo = 97 (48.7) Female, n(%) per arm: Sativex = 194 (47.0) Placebo = 102 (51.3))