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List of results

• Gujral et al. (2001): Efficacy of hydrolytic enzymes in preventing radiation therapy-induced side effects in patients with head and neck cancers  + (Gender per arm: Enzyme-arm: male= 34(64%); female= 16(36%) Control-arm: male= 35(74%); female= 12(26%))
• Okabayashi et al. (2020): L-Carnitine Improves Postoperative Liver Function in Hepatectomized Patients  + (Intervention arm 67%, control arm 67.6% male)
• Watanabe et al. (2010): Polaprezinc prevents oral mucositis associated with radiochemotherapy in patients with head and neck cancer  + (Intervention arm: 13 male, 3 female Control arm: 11 male, 4 female)
• Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial  + (Intervention arm: 16 % woman; Placebo arm: 16 % woman)
• Hajimohammadebrahim-Ketabforoush et al. (2019): Effect of Vitamin D Supplementation on Postcraniotomy Pain After Brain Tumor Surgery: A Randomized Clinical Trial  + (Intervention arm: 16 (53.3%) male Control arm: 14 (46.7%) male)
• Raoufinejad et al. (2019): Oral calcitriol in hematopoietic recovery and survival after autologous stem cell transplantation: a randomized clinical trial  + (Intervention arm: 25 (62.5%) male, 15 (37.5%) female placebo arm: 29 (72.5%), 15 (37.5%) female)
• Sangthawan et al. (2015): Effects of zinc sulfate supplementation on cell-mediated immune response in head and neck cancer patients treated with radiation therapy  + (Intervention arm: 33 (92%) male, 3 (8%) female Placebo arm: 31 (86%) male, 5 (14%) female)
• Ribeiro et al. (2017): Effects of zinc supplementation on fatigue and quality of life in patients with colorectal cancer  + (Intervention arm: 4:6 (male: female) Placebo arm: 5:9 (male:female))
• Sangthawan et al. (2013): A randomized double-blind, placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patients  + (Intervention arm: 65 (90%) male, 7 (10%) female Placebo arm: 60 (83%) male, 12 (17%) female)
• Lichtmann et al. (2018): Results of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled Pain  + (Intervention arm: female n = 95 (48%) Placebo arm: female n = 88 (44.2%))
• Arbabi-kalati et al. (2012): Evaluation of the efficacy of zinc sulfate in the prevention of chemotherapy-induced mucositis: A double-blind randomized clinical trial  + (Intervention arm: n=12 female, n=13 male Placebo arm: n=12 female, n=13 male)
• Moslemi et al. (2014): Oral zinc sulphate and prevention of radiation-induced oropharyngealmucositis in patients with head and neck cancers: A double blind, randomized controlled clinical trial  + (Intervention arm: n=12 male, n=8 female placebo arm: n=9 male, n=8 female)
• Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis  + (Intervention arm: n=14 male, n=3 female Placebo arm: n=13 male, n=4 female)
• Gorgu et al. (2013): The effect of zinc sulphate in the prevention of radiation induced oral mucositis in patents with head and neck cancer  + (Intervention arm: n=15 male and n=1 female Control arm: n=24 male, n=0 female)
• Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial  + (Intervention arm: n=173 (69%) male, n=78 (31%) female placebo arm: n=103 (62%) male, n=63 (38%) female)
• Brown et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Body Composition among Patients with Advanced or Metastatic Colorectal Cancer: A Randomized Trial  + (Intervention arm: n=32 (64%) male, n=18 (36%) female; placebo arm: n=27 (49%) male, n=28 (51%) female)
• Lin et al. (2008): Effects of zinc supplementation on clinical outcomes in patients receiving radiotherapy for head and neck cancers: a double-blinded randomized study  + (Intervention arm: n=40 (81.6%) male, n=9 (18.4%) female Placebo arm: n=43 (89.6%) male, n=5 (10.4%) female)
• Lin et al. (2006): Zinc supplementation to improve mucositis and dermatitis in patients after radiotherapy for head-and-neck cancers: a double-blind, randomized study  + (Intervention arm: n=40 (81.6%) male, n=9 (18.4%) female Placebo arm: n=43 (89.6%) male, n=5 (10.4%) female)
• Ng et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial  + (Intervention arm: n=41 (59%) male, n=28 (41%) female; placebo arm: n=38 (54%) male, n=32 (46%) female)
• Paur et al. (2017): Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA  + (Male n (%): 86 (100))
• Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer  + (Male n (%): 92 (100))
• Lian et al. (2014): Comparing the Effectiveness of Green Tea versus Topical Metronidazole Powder in Malodorous Control of Fungating Malignant Wounds in a Controlled Randomised Study  + (Male n(%) per arm: Green tea arm: 2 (13), Metronidazole arm: 1 (7) Female n(%) per arm: Green tea arm: 13 (87), Metronidazole arm: 14 (93))
• Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy  + (Male n(%) per arm: Green tea arm: 9 (42.9), placebo arm: 14 (66.7) Female n(%) per arm: Green tea arm: 12 (57.1), placebo arm: 7 (33.3))
• Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer  + (Male n(%) per arm: Selenium arm: 25 (67.9), placebo arm: 25 (73.5) Female n(%) per arm: Selenium arm: 12 (32.1), placebo arm: 9 (26.5))
• Li et al. (2018): Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial  + (Male n(%) per group: ginger-group: 53 (74.65), placebo-group: 47 (68.12) Female n(%) per group: ginger-group: 18 (25.35), placebo-group: 22 (31.88))

• Büntzel et al. (2010): Limited effects of selenium in the prevention of radiation-associated toxicities - results of a randomized study in head neck cancer patients  + (Male n=31, female n=8)

• Strasser et al. (2006): Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled (…)  + (Male per arm: THC = 54% Cannabis extract = 56% Placebo = 52%)
• Freedland et al. (2020): A Randomized Controlled Trial of a 6-month low carbohydrate intervention on disease progression in men with recurrent prostate cancer: Carbohydrate and Prostate Study 2 (CAPS2)  + (Male, n (%): 57 (100))
• Fallon et al. (2017) I: Sativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studies  + (Male, n(%) per arm: Sativex = 106 (53.0) Placebo = 97 (48.7) Female, n(%) per arm: Sativex = 194 (47.0) Placebo = 102 (51.3))
• Bairati et al. (2005): A Randomized Trial of Antioxidant Vitamins to Prevent Second Primary Cancers in Head and Neck Cancer Patients  + (N (%) of men per arm: - intervention: 223 (82) - placebo: 203 (76))
• Bairati et al. (2005): Randomized Trial of Antioxidant Vitamins to Prevent Acute Adverse Effects of Radiation Therapy in Head and Neck Cancer Patients  + (N (%) of men per arm: - intervention: 223 (82) - placebo: 203 (76))
• Bairati et al. (2006): Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients  + (N (%) of men per arm: - intervention: 223 (82) - placebo: 203 (76))
• Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial  + (N (%) per arm: - intervention: 94 (90.4) male, 10 (9.6) female - control: 99 (90) male, 11 (10) female)
• Muecke et al. (2014): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology: follow-up analysis of the survival data 6 years after cessation of randomization  + (NA)
• Shamsaei et al. (2017): The Vitamin E Preventive Effect on Taxol-Induced Neuropathy Among Patients With Breast Cancer: A Randomized Clinical Trial  + (NA)
• Muecke et al. (2010): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology  + (NA)
• Hershman et al. (2013): Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy  + (NA)
• Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy  + (NA)
• Muecke et al. (2013): Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology-a subgroup analysis of a multicenter, phase III trial  + (NA)
• Margalit et al. (2012): Beta-carotene Antioxidant Use During Radiation Therapy and Prostate Cancer Outcome in the Physicians’ Health Study  + (NI)
• Büntzel et al. (2010): Selenium Substitution During Radiotherapy of Solid Tumours - Laboratory Data from Two Observation Studies in Gynaecological and Head and Neck Cancer Patients  + (NI)
• Kessels et al. (2017): Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma A Randomized Clinical Trial  + (NI)
• Dias et al. (2015): The chemopreventive effect of Ginkgo biloba extract 761 against cisplatin ototoxicity: a pilot study  + (NI)
• Dos Santos Martins (2016): Placebo-Controlled, Double-Blind, Randomized Study of a Dry Guarana Extract in Patients with Head and Neck Tumors Undergoing Chemoradiotherapy: Effects on Fatigue and Quality of Life  + (NI)
• Stauder et al. (1991): Strahlentherapeutische Nebenwirkungen bei Abdominalkrebspatienten und deren Reduktion durch hydrolytische Enzyme  + (NI)
• Sun et al. (2016): A prospective study to evaluate the efficacy and safety of oral acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy  + (NI)
• Özdelikara et al. (2017): The effect of reflexology on the quality of life with breast cancer patients  + (NI)
• Lin et al. (2010): Discrepancy of the effects of zinc supplementation on the prevention of radiotherapy-induced mucositis between patients with nasopharyngeal carcinoma and those with oral cancers: subgroup analysis of a double-blind, randomized study  + (Nasopharyngeal cancer: intervention arm: 17 (81.0%) male, 4 (19.0%) female Nasopharyngeal cancer: placebo arm: 15 (78.9%) male, 4 (21.1%) female Oral cancer: intervention arm: 19 (83.0%) male, 4 (17%) female Oral cancer: placebo arm: 20 (100%) male)
• Jyothirmayi et al. (1996): Efficacy of Vitamin A in the Prevention of Locoregional Recurrence and Second Primaries in Head and Neck Cancer  + (Number male, female per group: - intervention: 36/50, 14/50 - placebo: 37/50, 19/50)
• Liu et al. (2010): Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial  + (Number n (Male/Female): Arm A: 2/16 Arm B: 3/15 Arm C: 7/12 Arm D: 2/15)
• Ehrenpreis et al. (2005): A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy  + (Of the 17 analysed patients: 15 male, 2 female)