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- Newling et al. (1995): Tryptophan metabolites, pyridoxine (vitamin B6) and their influence on the recurrence rate of superficial bladder cancer. Results of a prospective, randomised phase III study performed by the EORTC GU Group + (Patients with histologically proven Ta/T1, … Patients with histologically proven Ta/T1, NO or NX, MO transitional cell carcinoma ofthe bladder completely removed by transurethral resection or fulguration before the start of oral therapy; no previous therapy other than transurethral resection or fulguration; estimated survival of more than 3 yearsn; estimated survival of more than 3 years)