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- Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects + ('''Urogenital side effects''' Patients wer … '''Urogenital side effects'''</br>Patients were evaluated at weekly intervals (for 5 weeks) for acute radiation therapy related side effects. Urogenital side effects were graded according to the RTOG/EORTC criteria, by a single observer (score 0-4). Patients were followed-up at intervals of 6 weeks and 5 month after completion of radiation therapy.nth after completion of radiation therapy.)