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List of results

Kasseroller et al. (2003): Efficacy and tolerability of proteolytic enzymes as an anti-inflammatory agent in lymphoedema after axillary dissection due to mammary cancer + ('''Skinfold thickness''' (Parameter of fib … '''Skinfold thickness'''(Parameter of fibrosis) was measured with a calliper in mm and devided by 2 for the normal measurement of the skinfold in not fibrotically changed skin. Measures of the absolute values were taken from the upper arm, the lower arm, the hand and from the third finger. The absolute reference value is 2 mms for the healthy skin.rence value is 2 mms for the healthy skin.)
Kasseroller et al. (2003): Efficacy and tolerability of proteolytic enzymes as an anti-inflammatory agent in lymphoedema after axillary dissection due to mammary cancer + ('''Tension''' Assessed by the investigator with a four point rating scale: 0 = no tension 1 = slight tension 2 = moderate tension 3 = severe tension)
Su et al. (2004): Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms + ('''Treatment interruptions''' Radiation interruptions because of mucositis.)
Wrbka et al. (1987): Unterstützung der Chemotherapie inoperabler Karzinome durch proteolytische Fermente + ('''Treatment success''' Based on the radiological findings and quality of life (improved if general condition increased and radiological findings remain the same or improved))
Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects + ('''Urogenital side effects''' Patients wer … '''Urogenital side effects'''Patients were evaluated at weekly intervals (for 5 weeks) for acute radiation therapy related side effects. Urogenital side effects were graded according to the RTOG/EORTC criteria, by a single observer (score 0-4). Patients were followed-up at intervals of 6 weeks and 5 month after completion of radiation therapy.nth after completion of radiation therapy.)
Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects + ('''Vaginal mucosal side effects''' Patient … '''Vaginal mucosal side effects'''Patients were evaluated at weekly intervals (for 5 weeks) for acute radiation therapy related side effects. Vaginal mucosal side effects were graded according to the RTOG/EORTC criteria, by a single observer (score 0-4). Patients were followed-up at intervals of 6 weeks and 5 month after completion of radiation therapy.nth after completion of radiation therapy.)
Kasseroller et al. (2003): Efficacy and tolerability of proteolytic enzymes as an anti-inflammatory agent in lymphoedema after axillary dissection due to mammary cancer + ('''Volume reduction''' measured by Volometer = opto-electronic device measures the arm circumference 2-dimensionally along a distance of 45cm on the entire arm according to the kuhnke formula. As reference the healthy arm of each individual is measured.)
Puataweepong et. al (2009): The efficacy of oral Aloe vera juice for radiation induced mucositis in head and neck cancer patients: a double-blind placebo-controlled study + ('''radiation breaks''')
Rostock et al. (2013): Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients: A Four-Arm Randomized Trial on the Effectiveness of Electroacupuncture + (- Extension and intensity (non, mild, mode … - Extension and intensity (non, mild, moderate,or severe) of CIPN complaints (numbness, swelling, tingling, pain, and subjective impairment in everyday life and at work)- Heaviness of suffering due to CIPN complaints- Severity of neuropathic symptoms-> Outcome change from day 0 of treatment until day 21 (after treatment)0 of treatment until day 21 (after treatment))
Chung et al. (2016): Randomized Trial of Vitamin C/E Complex for Prevention of Radiation- Induced Xerostomia in Patients with Head and Neck Cancer + (- Patient self-assessment by xerostomia questionnaire (XQ) - Xerostomia score assessed by observer (XS) - Salivary scintigraphy (maximum accumulation, ejection fraction and prestimulatory and poststimulatory oral index))
Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial + (10-year DFS)
Muecke et al. (2014): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology: follow-up analysis of the survival data 6 years after cessation of randomization + (10-year disease-free survival)
Muecke et al. (2014): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology: follow-up analysis of the survival data 6 years after cessation of randomization + (10-year overall survival)

Hershman et al. (2018): Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L Carnitine + (11-item neurotoxicity component (NTX) of the FACT-Taxane scale)

Del Giglio (2013): Purified Dry Extract of Paullinia cupana (Guarana) (PC-18) for Chemotherapy-Related Fatigue in Patients with Solid Tumors: An Early Discontinuation Study + (2 instances of grade 3 toxicity in the intervention arm, which was not reported with placebo)
Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597 + (5-year OS)
Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial + (5-year overall survival = elapsed time from the date of randomization (ie, time from starting the study medication to the date of death due to any cause), as well as incidence of relapse, cancer- specific death, and noncancer death)
Akiba et al. (2018): Vitamin D Supplementation and Survival of Patients with Non–small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial + (5-year overall survival: the time from the supplement start date to the date of death from any cause)
Akiba et al. (2018): Vitamin D Supplementation and Survival of Patients with Non–small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial + (5-year recurrence-free survival: the time from the supplement start date to the earlier date of relapse of cancer or death from any cause)
Zick et al. (2008): Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting + (?)
Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis + (?)
Watanabe et al. (2010): Polaprezinc prevents oral mucositis associated with radiochemotherapy in patients with head and neck cancer + (Ability to oral intake; Amount of daily meals)
Bairati et al. (2005): Randomized Trial of Antioxidant Vitamins to Prevent Acute Adverse Effects of Radiation Therapy in Head and Neck Cancer Patients + (Acute Adverse Effects of Radiation Therapy … Acute Adverse Effects of Radiation Therapy:most severe radiation therapy adverse effect with regards to baseline status, graded from 0 (no symptom) to 4 (severe symptom), in six sites (skin, mucosa, ear, salivary glands, pharynx and esophagus, and larynx)glands, pharynx and esophagus, and larynx))
Shokri et al. (2017): Comparison of the Complications of Platinum-Based Adjuvant Chemotherapy With and Without Ginger in a Pilot Study on Ovarian Cancer Patients + (Adverse effects)
Uysal et al. (2016): Effects of foot massage applied in two different methods on symptom control in colorectal cancer patients: Randomised control trial + (Adverse effects with CTCAE: pain, fatigue, nausea, vomiting, diarrhea, constipation, flatulence, urinary urgency and proctitis (week 1-5 of chemotherapy))
Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial + (Adverse events)
Beer et al. (2007): Double-blinded randomized study of high-dose calcitriol plus docetaxel compared with placebo plus docetaxel in androgen-independent prostate cancer: a report from the ASCENT Investigators + (All adverse events are reported regardless of perceived relationship to treatment)
Hodgson et al. (2012): Reflexology versus Swedish Massage to Reduce Physiologic Stress and Pain and Improve Mood in Nursing Home Residents with Cancer: A Pilot Trial. + (All endpoints are mean values formed from four surveys that took place over each intervention day Observation of state of mind AARS: Positive affect)
Shooriabi et al. (2016): The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: A double-blind controlled study + (Amount/weight of saliva, unstimulated)
Raoufinejad et al. (2019): Oral calcitriol in hematopoietic recovery and survival after autologous stem cell transplantation: a randomized clinical trial + (Anti-infective medicines in addition to usual care)
Frankling et al. (2021): ‘Palliative-D’ - Vitamin D Supplementation to Palliative Cancer Patients: A Double Blind, Randomized Placebo-Controlled Multicenter Trial + (Antibiotic use, measured as the number of days with antibiotics in the previous 30 days)
Del Giglio (2013): Purified Dry Extract of Paullinia cupana (Guarana) (PC-18) for Chemotherapy-Related Fatigue in Patients with Solid Tumors: An Early Discontinuation Study + (Anxiety and Depression)
Sharp et al. (2010): A randomised, controlled trial of the psychological effects of reflexology in early breast cancer + (Anxiety and Depression (Baseline, 18 weeks post surgery, 24 weeks post surgery))
Johnson et al. (2010): Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain + (Appetite)
Côté et al. (2016): Improving Quality of Life With Nabilone During Radiotherapy Treatments for Head and Neck Cancers: A Randomized Double-Blind Placebo-Controlled Trial + (Appetite with questionnaire (no further information))
Shapiro et al. (2016): Randomized, blinded trial of vitamin D3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS) + (Aromatase inhibitor-associated musculoskeletal symptoms)
Niravath et al. (2019): Randomized controlled trial of high‐dose versus standard‐dose vitamin D3 for prevention of aromatase inhibitor‐induced arthralgia + (Aromatase inhibitor-induced arthralgia)
Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial + (At 3 months)
Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial + (At baseline and T6 (Day 4 after chemotherapy))