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- Chung et al. (2016): Randomized Trial of Vitamin C/E Complex for Prevention of Radiation- Induced Xerostomia in Patients with Head and Neck Cancer + (- Patient self-assessment by xerostomia questionnaire (XQ) - Xerostomia score assessed by observer (XS) - Salivary scintigraphy (maximum accumulation, ejection fraction and prestimulatory and poststimulatory oral index))
- Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial + (10-year DFS)
- Muecke et al. (2014): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology: follow-up analysis of the survival data 6 years after cessation of randomization + (10-year disease-free survival)
- Muecke et al. (2014): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology: follow-up analysis of the survival data 6 years after cessation of randomization + (10-year overall survival)
- Hershman et al. (2018): Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L Carnitine + (11-item neurotoxicity component (NTX) of the FACT-Taxane scale)
- Del Giglio (2013): Purified Dry Extract of Paullinia cupana (Guarana) (PC-18) for Chemotherapy-Related Fatigue in Patients with Solid Tumors: An Early Discontinuation Study + (2 instances of grade 3 toxicity in the intervention arm, which was not reported with placebo)
- Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597 + (5-year OS)
- Urashima et al. (2019): Effect of Vitamin D Supplementation on Relapse-Free Survival Among Patients With Digestive Tract Cancers The AMATERASU Randomized Clinical Trial + (5-year overall survival = elapsed time from the date of randomization (ie, time from starting the study medication to the date of death due to any cause), as well as incidence of relapse, cancer- specific death, and noncancer death)
- Akiba et al. (2018): Vitamin D Supplementation and Survival of Patients with Non–small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial + (5-year overall survival: the time from the supplement start date to the date of death from any cause)
- Akiba et al. (2018): Vitamin D Supplementation and Survival of Patients with Non–small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial + (5-year recurrence-free survival: the time from the supplement start date to the earlier date of relapse of cancer or death from any cause)
- Zick et al. (2008): Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting + (?)
- Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis + (?)
- Watanabe et al. (2010): Polaprezinc prevents oral mucositis associated with radiochemotherapy in patients with head and neck cancer + (Ability to oral intake; Amount of daily meals)
- Bairati et al. (2005): Randomized Trial of Antioxidant Vitamins to Prevent Acute Adverse Effects of Radiation Therapy in Head and Neck Cancer Patients + (Acute Adverse Effects of Radiation Therapy … Acute Adverse Effects of Radiation Therapy:</br>most severe radiation therapy adverse effect with regards to baseline status, graded from 0 (no symptom) to 4 (severe symptom), in six sites (skin, mucosa, ear, salivary glands, pharynx and esophagus, and larynx)glands, pharynx and esophagus, and larynx))
- Shokri et al. (2017): Comparison of the Complications of Platinum-Based Adjuvant Chemotherapy With and Without Ginger in a Pilot Study on Ovarian Cancer Patients + (Adverse effects)
- Uysal et al. (2016): Effects of foot massage applied in two different methods on symptom control in colorectal cancer patients: Randomised control trial + (Adverse effects with CTCAE: pain, fatigue, nausea, vomiting, diarrhea, constipation, flatulence, urinary urgency and proctitis (week 1-5 of chemotherapy))
- Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial + (Adverse events)
- Beer et al. (2007): Double-blinded randomized study of high-dose calcitriol plus docetaxel compared with placebo plus docetaxel in androgen-independent prostate cancer: a report from the ASCENT Investigators + (All adverse events are reported regardless of perceived relationship to treatment)
- Hodgson et al. (2012): Reflexology versus Swedish Massage to Reduce Physiologic Stress and Pain and Improve Mood in Nursing Home Residents with Cancer: A Pilot Trial. + (All endpoints are mean values formed from four surveys that took place over each intervention day Observation of state of mind AARS: Positive affect)
- Shooriabi et al. (2016): The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: A double-blind controlled study + (Amount/weight of saliva, unstimulated)
- Raoufinejad et al. (2019): Oral calcitriol in hematopoietic recovery and survival after autologous stem cell transplantation: a randomized clinical trial + (Anti-infective medicines in addition to usual care)
- Frankling et al. (2021): ‘Palliative-D’ - Vitamin D Supplementation to Palliative Cancer Patients: A Double Blind, Randomized Placebo-Controlled Multicenter Trial + (Antibiotic use, measured as the number of days with antibiotics in the previous 30 days)
- Del Giglio (2013): Purified Dry Extract of Paullinia cupana (Guarana) (PC-18) for Chemotherapy-Related Fatigue in Patients with Solid Tumors: An Early Discontinuation Study + (Anxiety and Depression)
- Sharp et al. (2010): A randomised, controlled trial of the psychological effects of reflexology in early breast cancer + (Anxiety and Depression (Baseline, 18 weeks post surgery, 24 weeks post surgery))
- Johnson et al. (2010): Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain + (Appetite)
- Côté et al. (2016): Improving Quality of Life With Nabilone During Radiotherapy Treatments for Head and Neck Cancers: A Randomized Double-Blind Placebo-Controlled Trial + (Appetite with questionnaire (no further information))
- Shapiro et al. (2016): Randomized, blinded trial of vitamin D3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS) + (Aromatase inhibitor-associated musculoskeletal symptoms)
- Niravath et al. (2019): Randomized controlled trial of high‐dose versus standard‐dose vitamin D3 for prevention of aromatase inhibitor‐induced arthralgia + (Aromatase inhibitor-induced arthralgia)
- Jahangard-Rafsanjani et al. (2013): The efficacy of selenium in prevention of oral mucositis in patients undergoing hematopoietic SCT: a randomized clinical trial + (At 3 months)
- Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial + (At baseline and T6 (Day 4 after chemotherapy))
- Jeon et al. (2016): Effect of intravenous high dose Vitamin C on postoperative pain and morphine use after laparoscopic colectomy: A randomized controlled trial + (At rest and while coughing Pain at 2h, 6h and 24h)
- Villani et al. (2016): Vitamin E neuroprotection against cisplatin ototoxicity: Preliminary results from a randomized, placebo-controlled trial + (Audiograms 2000/4000/8000 Hz and evoked brainstem responses)
- Stauder et al. (1991): Strahlentherapeutische Nebenwirkungen bei Abdominalkrebspatienten und deren Reduktion durch hydrolytische Enzyme + (Average tolerability scored by patient and doctor on a scale from 1=very good to 5=bad; Therpy result scored by patient and doctor on a scale from 1 to 4=unsatisfactory)
- Kraft et al. (2012): L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial + (BMI and body composition (BIA) : baseline + 6, 12 weeks)
- Khodabakhshi et al. (2019): Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study + (BMI, body weight, fat (%))
- Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial + (Baseline + every 2 months (for 3 years), then every 4 months (up to the 5th year), then twice a year)
- Özdelikara et al. (2017): The Effect of Reflexology on Chemotherapy-induced Nausea, Vomiting, and Fatigue in Breast Cancer Patients + (Baseline within 24h after the 1st chemothe … Baseline within 24h after the 1st chemotherapy cycle and three further posttreamtent measurements, each 24h after the 2nd-4th chemotherapy cycle. Baseline within 24h after the 1st chemotherapy cycle and three further posttreamtent measurements, each 24h after the 2nd-4th chemotherapy cycle. </br>INVR: Subscale of experienceerapy cycle. INVR: Subscale of experience)
- Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. + (Baseline, Follow-up)
- Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. + (Baseline, Follow-up)
- Tsay et al. (2008): Effects of Reflexotherapy on Acute Postoperative Pain and Anxiety Among Patients With Digestive Cancer. + (Baseline; T1-T3 (Day 2 post surgery - Day 4 post surgery, follow-up) Value; coefficient of the time x group interaction effect βI (standard error),p-value)
- Dyer et al. (2013): Is reflexology as effective as aromatherapy massage for symptom relief in an adult outpatient oncology population? + (Before and after the 4 sessions: Change in values before and after treatment at the respective 4 points in time)
- Minchom et al. (2014): An unblinded, randomised phase II study of platinum-based chemotherapy with vitamin B12 and folic acid supplementation in the treatment of lung cancer with plasma homocysteine blood levels as a biomarker of (...) + (Before the start of chemotherapy, every 6 weeks during chemotherapy, then every 3 months for up to 1 year Measures: EORTC QLQ-C30 (V.3) and Lung module QLQ-LC13)
- Lin et al. (2009): Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: follow-up of a double-blind randomized study with subgroup analysis + (Between the time of first treatment and th … Between the time of first treatment and the time of local recurrence or distant metastases;</br></br>Subgroup analysis: no significant difference between the arms for the 5-year DFS among the patients with stages III to IV head and neck cancers other than nasopharyngeal carcinoma (p = .752)r than nasopharyngeal carcinoma (p = .752))
- Zick et al. (2008): Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting + (Blinding)
- Stendell-Hollis et al. (2010): Green tea improves metabolic biomarkers, not weight or body composition: a pilot study in overweight breast cancer survivors + (Body composition measurements (mean percentage body fat and lean mass) were assessed using dual energy X-ray absorptiometry (DXA) in accordance with standardised procedures under the direction of a certified radiation technician.)
- Sangthawan et al. (2013): A randomized double-blind, placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patients + (Body weight)
- Brown et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Body Composition among Patients with Advanced or Metastatic Colorectal Cancer: A Randomized Trial + (Body weight, body mass index, muscle area, muscle attenuation, visceral adipose tissue area and subcutaneous adipose tissue area)
- Stendell-Hollis et al. (2010): Green tea improves metabolic biomarkers, not weight or body composition: a pilot study in overweight breast cancer survivors + (Body weight, height and waist and hip circumference were measured following standardised protocols (Khosla & Lowe, 1967; Lean et al., 1995))
- Rastelli et al. (2011): Vitamin D and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial + (Bone Mineral Density of the lumbar spine, total femur, and femoral neck)
- Johnson et al. (2010): Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain + (Breakthrough pain and corresponding opioid intake and daily opioid use with diary Numeric Rating Scale (NRS) over the last 24h)
- Wyatt et al. (2012): Health-Related Quality-of-Life Outcomes: A Reflexology Trial With Patients With Advanced-Stage Breast Cancer + (Breast cancer-specific QOL with FACT-B: physical, emotional, social, functional, breast cancer-specific concerns subscales and total scale)