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List of results

• Muecke et al. (2013): Impact of treatment planning target volumen (PTV) size on radiation induced diarrhoea following selenium supplementation in gynecologic radiation oncology-a subgroup analysis of a multicenter, phase III trial  + (NA)
• Afonseca et al. (2013): Vitamin E for prevention of oxaliplatin-induced peripheral neuropathy: A pilot randomized clinical trial  + (NI)
• Walsh et al. (2010): Use of alpha,25-dihydroxyvitamin D3 treatment to stimulate immune infiltration into head and neck squamous cell carcinoma  + (NI)
• Dias et al. (2015): The chemopreventive effect of Ginkgo biloba extract 761 against cisplatin ototoxicity: a pilot study  + (NI)
• Yekta et al. (2012): Ginger as a miracle against chemotherapy-induced vomiting  + (NI)
• Sontakke et al. (2003): Ginger as an antiemetic in nausea and vomiting induced by chemotherapy: A randomized, cross-over, double blind study  + (NI)
• Ansari et al. (2016): Efficacy of Ginger in Control of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients Receiving Doxorubicin- Based Chemotherapy  + (NI)
• Sanaati et al. (2016): Effect of Ginger and Chamomile on Nausea and Vomiting Caused by Chemotherapy in Iranian Women with Breast Cancer  + (NI)
• Salihah et al. (2016): The effectiveness of inhaled ginger essential oil in improving dietary intake in breast-cancer patients experiencing chemotherapy-induced nausea and vomiting  + (NI)
• Raei et al. (2013): Effect of herbal therapy to intensity chemotherapy-induced nausea and vomiting in cancer patients  + (NI)
• Özdelikara et al. (2017): The Effect of Reflexology on Chemotherapy-induced Nausea, Vomiting, and Fatigue in Breast Cancer Patients  + (NI)
• Özdelikara et al. (2017): The effect of reflexology on the quality of life with breast cancer patients  + (NI)
• Stephenson et al. (2000): The Effects of Foot Reflexology on Anxiety and Pain in Patients With Breast and Lung Cancer.  + (NI)
• Stephenson et al. (2017): Partner-delivered reflexology: Effects on cancer pain and anxiety.  + (NI)
• Uysal et al. (2016): Effects of foot massage applied in two different methods on symptom control in colorectal cancer patients: Randomised control trial  + (NI)
• Laali et al. (2020): Effect of Selenium on Incidence and Severity of Mucositis during Radiotherapy in Patients with Head and Neck Cancer  + (Oral mucositis T0: Baseline Follow up: weekly for 7 weeks Selenium level T0: Baseline T1: End of radiation)
• Howells et al. (2011): Phase I randomised double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases - safety, pharmacokinetics and pharmacodynamics  + (Patients ingested the formulation pre-oper … Patients ingested the formulation pre-operatively daily for a minimum of 10 and a maximum of 21 days, dependent upon surgical scheduling. Plasma samples for PK assessment were obtained on days 1 and 2, and on the day of surgical resection. Plasma for PD assessment was obtained pre-dose, immediately prior to, and during surgery. Diseased and normal adjacent hepatic tissue was resected 6-7 h after the last dose.ue was resected 6-7 h after the last dose.)
• Büntzel et al. (2010): Selenium Substitution During Radiotherapy of Solid Tumours - Laboratory Data from Two Observation Studies in Gynaecological and Head and Neck Cancer Patients  + (Selenium concentration measured at baseline, after 4 weeks, after the end of radiotherapy and 6 weeks after the end of radiotherapy Overall duration: 7 weeks of radiotherapy)
• Büntzel et al. (2010): Limited effects of selenium in the prevention of radiation-associated toxicities - results of a randomized study in head neck cancer patients  + (Selenium concentration measured at baseline, after 4 weeks, after the end of Radiotherapy and 6 weeks after the end of Radiotherapy Outcome assessed at baseline and then once a week and 6 weeks after Radiotherapy)
• Karp et al. (2012): Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597  + (Study period: October 6, 2000 - November 5, 2009)
• Crew et al. (2012): Phase IB Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Women with Hormone Receptor–Negative Breast Cancer  + (T0 = Baseline T1 = after 6 month)
• Wyatt et al. (2017): A Randomized Clinical Trial of Caregiver-Delivered Reflexology for Symptom Management During Breast Cancer Treatment  + (T0 = Baseline T1 = week 1; T2: week 2; T3: week 3; T4: week 4)

• Campos et al. (2011): Guarana (Paullinia cupana) Improves Fatigue in Breast Cancer Patients Undergoing Systemic Chemotherapy  + (T0 = Baseline T1 = Day 21 (after phase 1) T2 = Day 49 (after phase 2))

• Upadhyaya et al. (2017): Radioprotective effect of vitamin E on salivary glands after radioiodine therapy for differential thyroid cancer: A randomized-controlled trial  + (T0: -4h radioiodine therapy T1: after 6 months)
• Dyer et al. (2013): Is reflexology as effective as aromatherapy massage for symptom relief in an adult outpatient oncology population?  + (T0: 1st intervention T1: 2nd intervention T2: 3rd intervention T3: 4th intervention)
• Sharp et al. (2010): A randomised, controlled trial of the psychological effects of reflexology in early breast cancer  + (T0: 6 weeks post surgery; T1: 18 weeks post surgery; T2: 24 weeks post surgery)
• Akiba et al. (2018): Vitamin D Supplementation and Survival of Patients with Non–small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial  + (T0: Baseline)
• Tan et al. (2018): Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor  + (T0: Baseline T1: 1 day after surgery T2: 3 days after surgery T3: 7 days after surgery (+quality of life))
• Muecke et al. (2010): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology  + (T0: Baseline T1: Half of the radiotherapy (about 4 weeks) T2: End of radiotherapy T3: 6 weeks after radiotherapy)
• Mansouri et al. (2016): The Effect of Aloe Vera Solution on Chemotherapy-Induced Stomatitis in Clients with Lymphoma and Leukemia: A Randomized Controlled Clinical Trial  + (T0: Baseline T1: day 1 T2: day 3 T3: day 5 T4: day 7 T5: day 14)
• Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects  + (T0: Baseline T1: weekly for 5 weeks Follow-up: after 6 weeks and 5 month after intervention)
• Johansson et al. (2021): Vitamin D Supplementation and Disease-Free Survival in Stage II Melanoma: A Randomized Placebo Controlled Trial  + (T0: Baseline 13 follow-up visits (4th, 8th, 12th, 16th, 20th, 24th, 28th, 32nd, 36th, 42nd, 48th, 54th, and 60th month))
• Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study  + (T0: Baseline At 6, 12, 18 and 24 months)
• Van Zandwijk et al. (2000): EUROSCAN, a Randomized Trial of Vitamin A and N-Acetylcysteine in Patients With Head and Neck Cancer or Lung Cancer  + (T0: Baseline Follop-up: at least 2 years after randomization)
• Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial  + (T0: Baseline Follow-up, median (range) per arm: - intervention: 61 (1-116) month - control: 58 (1-123) month)
• Meyskens et al. (1995): Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial  + (T0: Baseline Follow-up, median (range): 76 (37-111) months)
• Attia et al. (2008): Randomized, Double-Blinded Phase II Evaluation of Docetaxel with or without Doxercalciferol in Patients with Metastatic, Androgen-Independent Prostate Cancer  + (T0: Baseline On day 1 of every 28-day cycle)
• Argyriou et al. (2006): A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results  + (T0: Baseline T1 or T2: after 3rd or 6th chemotherapy cycle T3: 3 months post-chemotherapy)
• Argyriou et al. (2006): Preventing Paclitaxel-Induced Peripheral neuropathy: A Phase 2 Trial of Vitamin E Supplementation  + (T0: Baseline T1 or T2: after 3rd or 6th chemotherapy cycle T3: 3 months post-chemotherapy)
• Frankling et al. (2021): ‘Palliative-D’ - Vitamin D Supplementation to Palliative Cancer Patients: A Double Blind, Randomized Placebo-Controlled Multicenter Trial  + (T0: Baseline T1-T3: every worth week)
• Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy  + (T0: Baseline T1: * Diarrhea and vomiting … T0: Baseline</br>T1: </br>* Diarrhea and vomiting scaling weekly for 4 weeks (2nd-5th) </br>* daily diary (number, consistency of stools, occurrence of symptoms such as nausea, vomiting and gastrointestinal cramps) from day 1 of the 2nd week to the end of the 5th weekof the 2nd week to the end of the 5th week)
• Henning et al. (2015): Randomized Clinical Trial of Brewed Green and Black Tea in Men With Prostate Cancer Prior to Prostatectomy  + (T0: Baseline T1: Green tea arm: after an average of 33 days Black tea arm: after an average of 31 days Water arm: after an average of 29 days)
• Villani et al. (2016): Vitamin E neuroprotection against cisplatin ototoxicity: Preliminary results from a randomized, placebo-controlled trial  + (T0: Baseline T1: 1 month T2: 2 month T3: 3 month)
• Hershman et al. (2018): Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L Carnitine  + (T0: Baseline T1: 12th week T2: 24th week T3: 36th week T4: 52nd week T5: 104th week)
• Ehrenpreis et al. (2005): A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy  + (T0: Baseline T1: 30 Tage T2: 60 tage T3: 90 Tage)
• Khodabakhshi et al. (2019): Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study  + (T0: Baseline T1: 3rd visit (after about 9 weeks) T2: after 3 months)
• Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia  + (T0: Baseline T1: 4 weeks T2: 8 weeks T3: 16 weeks)
• Li et al. (2018): Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial  + (T0: Baseline T1: Acute symptoms 2 days after chemotherapy T2: 5 days after chemotherapy)