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- Akiba et al. (2018): Vitamin D Supplementation and Survival of Patients with Non–small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial + (T0: Baseline)
- Tan et al. (2018): Bromelain has significant clinical benefits after extraction of the third molar during chemotherapy in patients with hematologic tumor + (T0: Baseline T1: 1 day after surgery T2: 3 days after surgery T3: 7 days after surgery (+quality of life))
- Muecke et al. (2010): Multicenter, phase 3 trial comparing selenium supplementation with observation in gynecologic radiation oncology + (T0: Baseline T1: Half of the radiotherapy (about 4 weeks) T2: End of radiotherapy T3: 6 weeks after radiotherapy)
- Mansouri et al. (2016): The Effect of Aloe Vera Solution on Chemotherapy-Induced Stomatitis in Clients with Lymphoma and Leukemia: A Randomized Controlled Clinical Trial + (T0: Baseline T1: day 1 T2: day 3 T3: day 5 T4: day 7 T5: day 14)
- Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects + (T0: Baseline T1: weekly for 5 weeks Follow-up: after 6 weeks and 5 month after intervention)
- Johansson et al. (2021): Vitamin D Supplementation and Disease-Free Survival in Stage II Melanoma: A Randomized Placebo Controlled Trial + (T0: Baseline 13 follow-up visits (4th, 8th, 12th, 16th, 20th, 24th, 28th, 32nd, 36th, 42nd, 48th, 54th, and 60th month))
- Jacot et al. (2016): Impact of a tailored oral vitamin D supplementation regimen on serum 25-hydroxyvitamin D levels in early breast cancer patients: a randomized phase III study + (T0: Baseline At 6, 12, 18 and 24 months)
- Van Zandwijk et al. (2000): EUROSCAN, a Randomized Trial of Vitamin A and N-Acetylcysteine in Patients With Head and Neck Cancer or Lung Cancer + (T0: Baseline Follop-up: at least 2 years after randomization)
- Toma et al. (2003): β-carotene supplementation in patients radically treated for stage I-II head and neck cancer: Results of a randomized trial + (T0: Baseline Follow-up, median (range) per arm: - intervention: 61 (1-116) month - control: 58 (1-123) month)
- Meyskens et al. (1995): Effects of vitamin A on survival in patients with chronic myelogenous leukemia: a SWOG randomized trial + (T0: Baseline Follow-up, median (range): 76 (37-111) months)
- Attia et al. (2008): Randomized, Double-Blinded Phase II Evaluation of Docetaxel with or without Doxercalciferol in Patients with Metastatic, Androgen-Independent Prostate Cancer + (T0: Baseline On day 1 of every 28-day cycle)
- Argyriou et al. (2006): A randomized controlled trial evaluating the efficacy and safety of vitamin E supplementation for protection against cisplatin-induced peripheral neuropathy: final results + (T0: Baseline T1 or T2: after 3rd or 6th chemotherapy cycle T3: 3 months post-chemotherapy)
- Argyriou et al. (2006): Preventing Paclitaxel-Induced Peripheral neuropathy: A Phase 2 Trial of Vitamin E Supplementation + (T0: Baseline T1 or T2: after 3rd or 6th chemotherapy cycle T3: 3 months post-chemotherapy)
- Frankling et al. (2021): ‘Palliative-D’ - Vitamin D Supplementation to Palliative Cancer Patients: A Double Blind, Randomized Placebo-Controlled Multicenter Trial + (T0: Baseline T1-T3: every worth week)
- Emami et al. (2014): Double-blinded, randomized, placebo-controlled study to evaluate the effectiveness of green tea in preventing acute gastrointestinal complications due to radiotherapy + (T0: Baseline T1: * Diarrhea and vomiting … T0: Baseline</br>T1: </br>* Diarrhea and vomiting scaling weekly for 4 weeks (2nd-5th) </br>* daily diary (number, consistency of stools, occurrence of symptoms such as nausea, vomiting and gastrointestinal cramps) from day 1 of the 2nd week to the end of the 5th weekof the 2nd week to the end of the 5th week)
- Henning et al. (2015): Randomized Clinical Trial of Brewed Green and Black Tea in Men With Prostate Cancer Prior to Prostatectomy + (T0: Baseline T1: Green tea arm: after an average of 33 days Black tea arm: after an average of 31 days Water arm: after an average of 29 days)
- Villani et al. (2016): Vitamin E neuroprotection against cisplatin ototoxicity: Preliminary results from a randomized, placebo-controlled trial + (T0: Baseline T1: 1 month T2: 2 month T3: 3 month)
- Hershman et al. (2018): Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L Carnitine + (T0: Baseline T1: 12th week T2: 24th week T3: 36th week T4: 52nd week T5: 104th week)
- Ehrenpreis et al. (2005): A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy + (T0: Baseline T1: 30 Tage T2: 60 tage T3: 90 Tage)
- Khodabakhshi et al. (2019): Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study + (T0: Baseline T1: 3rd visit (after about 9 weeks) T2: after 3 months)
- Mantovani et al. (2010): Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia + (T0: Baseline T1: 4 weeks T2: 8 weeks T3: 16 weeks)
- Li et al. (2018): Efficacy of Ginger in Ameliorating Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Among Patients With Lung Cancer Receiving Cisplatin-Based Regimens: A Randomized Controlled Trial + (T0: Baseline T1: Acute symptoms 2 days after chemotherapy T2: 5 days after chemotherapy)
- Zick et al. (2008): Phase II trial of encapsulated ginger as a treatment for chemotherapy-induced nausea and vomiting + (T0: Baseline T1: After 1 hour of completion of chemotherapy T2: 3 days after the end of their chemotherapy treatment)
- Rastelli et al. (2011): Vitamin D and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial + (T0: Baseline T1: At 2 months T2: At 4 months T3: At 6 months)
- Uthaipaisanwong et al. (2020): Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study + (T0: Baseline T1: Day 1 of chemotherapy T2: Day 2-5 of chemotherapy)
- Asfour et al. (2006): Effect of high-dose sodium selenite therapy on polymorphonuclear leukocyte apoptosis in non-Hodgkin's lymphoma patients + (T0: Baseline T1: Day 3 T2: Day 8)
- Margalit et al. (2012): Beta-carotene Antioxidant Use During Radiation Therapy and Prostate Cancer Outcome in the Physicians’ Health Study + (T0: Baseline T1: Follow-up, median (range): 10.5 years (0.3-27.2))
- Mayne et al. (2001): Randomized Trial of Supplemental beta-Carotene to Prevent Second Head and Neck Cancer + (T0: Baseline T1: Follow-up, median (range): 51.1 (30-90) months)
- Wrbka et al. (1987): Unterstützung der Chemotherapie inoperabler Karzinome durch proteolytische Fermente + (T0: Baseline T1: On average 2 weeks (1-4 weeks))
- Cohen et al. (2018): Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial + (T0: Baseline T1: after 12 weeks)
- Chan et al. (2011): Nutritional supplements, COX-2 and IGF-1 expression in men on active surveillance for prostate cancer + (T0: Baseline T1: after 12 weeks)
- Stauder et al. (1991): Strahlentherapeutische Nebenwirkungen bei Abdominalkrebspatienten und deren Reduktion durch hydrolytische Enzyme + (T0: Baseline T1: after 2 weeks T2: after 5 weeks)
- Kessels et al. (2017): Topical Sinecatechins, 10%, Ointment for Superficial Basal Cell Carcinoma A Randomized Clinical Trial + (T0: Baseline T1: after 3 weeks T2: after 6 weeks T3: after 8 weeks (directly before operation))
- Pace et al. (2010): Vitamin E neuroprotection for cisplatin neuropathy + (T0: Baseline T1: after 3. chemotherapy cycle T2: 1 month post-chemotherapy)
- Cruciani et al. (2012): L-Carnitine Supplementation for the Management of Fatigue in Patients With Cancer: An Eastern Cooperative Oncology Group Phase III, Randomized, Double-Blind, Placebo-Controlled Trial + (T0: Baseline T1: after 4 weeks (first phase) T2: after 8 weeks (second phase))
- Stendell-Hollis et al. (2010): Green tea improves metabolic biomarkers, not weight or body composition: a pilot study in overweight breast cancer survivors + (T0: Baseline T1: after 6 month)
- Zalat et al. (2020): Evaluation of the cardioprotective effects of l-carnitine and silymarin in cancer patients receiving anthracycline-containing chemotherapy + (T0: Baseline T1: after 6 months of chemotherapy)
- Lian et al. (2014): Comparing the Effectiveness of Green Tea versus Topical Metronidazole Powder in Malodorous Control of Fungating Malignant Wounds in a Controlled Randomised Study + (T0: Baseline T1: after 7 days)
- Nguyen et al. (2012): Randomized, Double-Blind, Placebo-Controlled Trial of Polyphenon E in Prostate Cancer Patients before Prostatectomy: Evaluation of Potential Chemopreventive Activities + (T0: Baseline T1: after an average of 3 to 6 weeks until the operation)
- Dörr et al. (2007): Efficacy of Wobe-Mugos E for Reduction of Oral Mucositis after Radiotherapy + (T0: Baseline T1: after at least 6 weeks)
- Azizi et al. (2015): Efficacy of Topical and Systemic Vitamin E in Preventing Chemotherapy-induced Oral Mucositis + (T0: Baseline T1: after first cycle T2: after second cycle T3: after third cycle T4: after fourth cycle)
- Jyothirmayi et al. (1996): Efficacy of Vitamin A in the Prevention of Locoregional Recurrence and Second Primaries in Head and Neck Cancer + (T0: Baseline T1: after three years)
- Najafizade et al. (2013): Preventive effects of zinc sulfate on taste alterations in patients under irradiation for head and neck cancers: A randomized placebo-controlled trial + (T0: Baseline T1: at the end of radiotherapy Follow-Up: a month later)
- Khan et al. (2017): Randomized trial of vitamin D3 to prevent worsening of musculoskeletal symptoms in women with breast cancer receiving adjuvant letrozole. The VITAL trial + (T0: Baseline T1: at week 12 T2: at week 24)
- Gujral et al. (2001): Efficacy of hydrolytic enzymes in preventing radiation therapy-induced side effects in patients with head and neck cancers + (T0: Baseline T1: weekly for 8 weeks during radiation Follow up 1: 6-8 weeks after end of radiation Follow-up 2: 2-3 month after end of radiation Follow-up 3: 5-6 month after end of radiation)
- Lissoni et al. (2009): A Randomized Study of Chemotherapy versus Biochemotherapy with Chemotherapy plus Aloe arborescens in Patients with Metastatic Cancer + (T0: Baseline T1: weekly until progression of diasease Follow-up: after 3 years)
- Marucci et al. (2017): Double-blind randomized phase III study comparing a mixture of natural agents versus placebo in the prevention of acute mucositis during chemoradiotherapy for head and neck cancer + (T0: Baseline T1: weekly visits for 6 weeks)
- Mix et al. (2015): Randomized phase II trial of selenomethionine as a modulator of efficacy and toxicity of chemoradiation in squamous cell carcinoma of the head and neck + (T0: Baseline T1: Week 4 T2: Week 7 during treatment T3: Week 6-8 post-treatment T4: Follow-up 3 months after completion of the study and then at further 3-month intervals over 2 years, then every 6 months until 5 years thereafter)
- Mansourian et al. (2015): The effect of "curcuma Longa" topical gel on radiation -induced oral mucositis in patients with head and neck cancer + (T0: Baseline T1-T3: Tag 7, 14, 21)
- Dos Santos Martins (2016): Placebo-Controlled, Double-Blind, Randomized Study of a Dry Guarana Extract in Patients with Head and Neck Tumors Undergoing Chemoradiotherapy: Effects on Fatigue and Quality of Life + (T0: Baseline T1: After 3 weeks T2: After 6 weeks T3: After 9 weeks)
- Shooriabi et al. (2016): The effect of ginger extract on radiotherapy-oriented salivation in patients with xerostomia: A double-blind controlled study + (T0: Baseline T1: End of study)