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- Jatoi et al. (2002): Dronabinol Versus Megestrol Acetate Versus Combination Therapy for Cancer-Associated Anorexia: A North Central Cancer Treatment Group Study + (T0: baseline T1: end of study (no clear end of study defined))
- Niravath et al. (2019): Randomized controlled trial of high‐dose versus standard‐dose vitamin D3 for prevention of aromatase inhibitor‐induced arthralgia + (T0: baseline T1: week 12 T2: week 52)
- Keshavarzi et al. (2019): The effect of vitamin D and E vaginal suppositories on tamoxifen-induced vaginal atrophy in women with breast cancer + (T0: baseline T1: week 2 T2: week 4 T3: week 8)
- Grimison et al. (2020): Oral THC:CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting: a randomised, placebo-controlled, phase II crossover trial + (T0: baseline T1: one day before chemotherapy T2: day 8 of each cycle T3: between 30-42 days after end of intervention)
- Hoopfer et al. (2015): Three-arm randomized phase III trial: Quality aloe and placebo cream versus powder as skin treatment during breast cancer radiation therapy + (T0: baseline T1: weekly until end of radiation T2: week 1, 2, and 4 after end of radiation)
- Johnson et al. (2010): Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain + (T0: baseline (2 days) T1: after 7-10 days T2: after 14-20 days)
- Raoufinejad et al. (2019): Oral calcitriol in hematopoietic recovery and survival after autologous stem cell transplantation: a randomized clinical trial + (T0: baseline (day 0: allocation) T1: after 15 days T2: after 30 days T3: after 180 days T4: after 365 days Follow-up: 2 years)
- Heggie et al. (2002): A phase III study on the efficacy of topical aloe vera gel on irradiated breast tissue + (T0: baseline = day 1 of radiation treatment T1: weekly throughout radiation treatment Follow-up: 2 weeks after treatment)
- Antunac et al. (2018): Vitamin D Supplementation and Survival in Metastatic Colorectal Cancer + (T0: baseline before first cycle of chemotherapy afterwards: observation over 2 years or until death)
- Côté et al. (2016): Improving Quality of Life With Nabilone During Radiotherapy Treatments for Head and Neck Cancers: A Randomized Double-Blind Placebo-Controlled Trial + (T0: baseline before radiotherapy T1: first week T2: second week until T3: 7<sup>th</sup> week Follow-up: between 9<sup>th</sup> - 11<sup>th</sup> week)
- Ribeiro et al. (2017): Effects of zinc supplementation on fatigue and quality of life in patients with colorectal cancer + (T0: baseline before the beginning of supplementation T1-T4: before each of the four cycles of chemotherapy)
- Ng et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial + (T0: basline T1: after cycle 4 of chemotherapy (8 weeks) T2: after cycle 8 of chemotherapy (16 weeks) Follow-Up (End of study))
- Brown et al. (2019): Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Body Composition among Patients with Advanced or Metastatic Colorectal Cancer: A Randomized Trial + (T0: basline T1: after cycle 4 of chemotherapy (8 weeks) T2: after cycle 8 of chemotherapy (16 weeks) Follow-Up)
- Inglis et al. (2020): Effects of High-Dose Vitamin D Supplementation on Phase Angle and Physical Function in Patients with Prostate Cancer on ADT + (T0: basline T1: week 12 T2: week 24)
- Cruciani et al. (2009): L-Carnitine Supplementation in Patients with Advanced Cancer and Carnitine Deficiency: A Double-Blind, Placebo-Controlled Study + (T0: before intervention (baseline) T1: 2 weeks (end of phase 1) T2: 1 week after the start of the intervention T3: 4 weeks (end of phase 2))
- Hajimohammadebrahim-Ketabforoush et al. (2019): Effect of Vitamin D Supplementation on Postcraniotomy Pain After Brain Tumor Surgery: A Randomized Clinical Trial + (T0: before operation T1-T3: on day 1-3 after operation T4: on day 5 after operation)
- Sangthawan et al. (2013): A randomized double-blind, placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patients + (T0: before radiation weekly during radiation Follow-Up: 1 month after completion of radiation)
- Lin et al. (2010): Discrepancy of the effects of zinc supplementation on the prevention of radiotherapy-induced mucositis between patients with nasopharyngeal carcinoma and those with oral cancers: subgroup analysis of a double-blind, randomized study + (T0: before radiotherapy 1st Follow-Up at 3 months after radiotherapy 2nd Follow-Up at 12 months after radiotherapy)
- Gorgu et al. (2013): The effect of zinc sulphate in the prevention of radiation induced oral mucositis in patents with head and neck cancer + (T0: before radiotherapy Once a week during radiotherapy After radiotherapy)
- Ertekin et al. (2004): Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized study + (T0: before radiotherapy Once a week during treatment After treatment 6 weeks after treatment)
- Lin et al. (2006): Zinc supplementation to improve mucositis and dermatitis in patients after radiotherapy for head-and-neck cancers: a double-blind, randomized study + (T0: before radiotherapy T1: after radiotherapy 1st Follow-Up at 3 months after radiotherapy 2nd Follow-Up at 12 months after radiotherapy)
- Bairati et al. (2005): A Randomized Trial of Antioxidant Vitamins to Prevent Second Primary Cancers in Head and Neck Cancer Patients + (T0: before radiotherapy T1: during radiotherapy T2: immediately post-radiotherapy T3: 1 month post-radiotherapy from T4: every 6 months for 3 years, then once a year until 30.06.2003)
- Bairati et al. (2005): Randomized Trial of Antioxidant Vitamins to Prevent Acute Adverse Effects of Radiation Therapy in Head and Neck Cancer Patients + (T0: before radiotherapy T1: during radiotherapy T2: immediately post-radiotherapy T3: 1 month post-radiotherapy from T4: every 6 months for 3 years, then once a year until 30.06.2003)
- Bairati et al. (2006): Antioxidant vitamins supplementation and mortality: a randomized trial in head and neck cancer patients + (T0: before radiotherapy T1: during radiotherapy T2: immediately post-radiotherapy T3: 1 month post-radiotherapy from T4: every 6 months for 3 years, then once a year until 30.06.2003)
- Chung et al. (2016): Randomized Trial of Vitamin C/E Complex for Prevention of Radiation- Induced Xerostomia in Patients with Head and Neck Cancer + (T0: before radiotherapy, T1: 1 month post-radiotherapy, T2: 6 months post-radiotherapy)
- Delanian et al. (2003): Randomized, placebo-controlled trial of combined pentoxifylline and tocopherol for regression of superficial radiation-induced fibrosis + (T0: before randomization T1: after 3 months T2: after 6 months)
- Thamlikitkul et al. (2017): Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin–cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study + (T0: during first chemotherapy cycle T1: 0-24h (within 24h after chemotherapy) T2: >24h (after chemotherapy))
- Iovino et al. (2018): High-dose zinc oral supplementation after stem cell transplantation causes an increase of TRECs and CD4+ naive lymphocytes and prevents TTV reactivation + (T0: first day of stem cell collection T1: the day before the starting of the conditioning treatment T2: day +30 after transplant T3: day +100 after transplant)
- Braga et al. (2015): Effect of Zinc Supplementation on Serological Response to Vaccination Against Streptococcus Pneumoniae in Patients Undergoing Chemotherapy for Colorectal Cancer + (T0: perioperative (prior to vaccination) T1: before the chemotherapy (4th wk of study) T2: after 3 cycles of chemotherapy (16th wk of study))
- Koyama et al. (2017): Intravenous Carnitine Administration in Addition to Parenteral Nutrition With Lipid Emulsion May Decrease the Inflammatory Reaction in Postoperative Surgical Patients + (T0: preoperative phase T1: 1 day after surgery T2-T7: Day 2-7 after surgery Blood samples at T0, T1, T3 and T4; carnitine concentration at T0, T1, T3, T7; C-reactive protein (CRP) at T3 and T7, urine samples at T3 and T7)
- Ota et al. (2014): The effect of pyridoxine for prevention of hand-foot-syndrome in colorectal cancer patients with adjuvant chemotherapy using capecitabine: A randomized study + (T0: pretreatment T1: before each chemotherapy cycle T2: follow-up after chemotherapy)
- Pace et al. (2003): Neuroprotective Effect of Vitamin E Supplementation in Patient Treated With Cisplatin Chemotherapy + (T0: prior to chemotherapy T1: after 3. chemotherapy-cycle T2: 1 month after chemotherapy)
- Lyckholm et al. (2012): A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders + (T0: prior to intervention T1-T3: at 1, 2, and 3 months after initiating zinc versus placebo)
- Ripamonti et al. (1998): A randomized, controlled clinical trial to evaluate the effects of zinc sulfate on cancer patients with taste alterations caused by head and neck irradiation + (T0: prior to radiotherapy, weekly intervals during radiotherapy Follow-Up: 1 month after radiotherapy)
- Cavallini et al. (2005): Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy + (T0: prior to therapy T1: 4 month of therapy)
- Hejazi et al. (2013): A pilot clinical trial of radioprotective effects of curcumin supplementation in patients with prostate cancer + (T0: week -1 radiotherapy T1: 3 months after radiotherapy (20 weeks after T0))
- Hejazi et al. (2016): Effect of Curcumin Supplementation During Radiotherapy on Oxidative Status of Patients with Prostate Cancer: A Double Blinded, Randomized, Placebo-Controlled Study + (T0: week -1 radiotherapy T1: 3 months after radiotherapy (20 weeks after T0))
- Scher et al. (2011): Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancer + (T0: within 14 days of random assignment 72 hours preceding each day 2 Follow-Up: after 48 weeks (only for survival))
- Braik et al. (2014): Randomized trial of vitamin B6 for preventing hand-foot syndrome from capecitabine chemotherapy + (T1-T4: week 3 of each chemotherapy cycle)
- Panahi et al. (2012): Effect of Ginger on Acute and Delayed Chemotherapy-Induced Nausea and Vomiting: A Pilot, Randomized, Open-Label Clinical Trial + (T1: 0-6h after Chemotherapy T2: 6-24h after Chemotherapy T3: 2nd day T4: 3rd day T5: 4th day)
- Montazeri et al. (2013): Effect of Herbal Therapy to Intensity Chemotherapy-Induced Nausea and Vomiting in Cancer Patients + (T1: 1h after last capsule T2: after 2h T3: after 3h T4: after 4h T5: 24h after chemotherapy)
- Marx et al. (2017): The Effect of a Standardized Ginger Extract on Chemotherapy-Induced Nausea-Related Quality of Life in Patients Undergoing Moderately or Highly Emetogenic Chemotherapy: A Double Blind, Randomized, Placebo Controlled Trial + (T1: 1st cycle of chemotherapy (assessment from 3 days before to 4 days after) T2: 2nd cycle of chemotherapy (assessment from 3 days before to 4 days after) T3: 3rd cycle of chemotherapy (assessment from 3 days before to 4 days after))
- Bossi et al. (2017): A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin + (T1: Cycle 1 (day 2 to day 21 or 28) T2: Cycle 2 (day 23 or 30 to day 42 or 56))
- Fahimi et al. (2011): Evaluating the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens + (T1: Day 1 T2: Day 2 T3: Day 3)
- Arslan et al. (2015): Oral Intake of Ginger for Chemotherapy-Induced Nausea and Vomiting Among Women With Breast Cancer + (T1: Day 1 (i.e. day of the chemotherapy infusion) T2: Day 2 (i.e. day after chemotherapy infusion) T3: Day 3 T4: Day 4 T5: Day 5)
- Konmun et al. (2017): A phase II randomized double-blind placebo-controlled study of 6-gingerol as an anti-emetic in solid tumor patients receiving moderately to highly emetogenic chemotherapy + (T1: Day 1 (i.e. first day of chemotherapy administration) T2: Day 2 T3: Day 3 T4: Day 4 T5: Day 5 T6: Day 22 T7: Day 43 T8: Day 64)
- Mondal et al. (2014): Comparative study among glutamine, acetyl-L-carnitine, vitamin-E and methylcobalamine for treatment of paclitaxel-induced peripheral neuropathy + (T1: after 3 chemotherapy cycles T2: after 6 chemotherapy cycles T3: 6 months post-chemotherapy)
- Portenoy et al. (2012): Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial + (T1: baseline (3 days) T2: day 21 T3: day 35 (end of intervention) T4: 14 days after treatment)
- Paur et al. (2017): Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA + (T1: before intervention T2: after intervention (directly before radiotherapy/surgery))
- Puri et al. (2010): Lycopene in treatment of high-grade gliomas: A pilot study + (T1: pre-radiotherapy T2: post-radiotherapy T3: 6 months after radiotherapy)
- Mahmoodnia et al. (2017): Ameliorative effect of lycopene effect on cisplatin-induced nephropathy in patients + (T1: start of the study T2: day 7 of chemotherapy T3: day 21 of chemotherapy)