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- Ripamonti et al. (1998): A randomized, controlled clinical trial to evaluate the effects of zinc sulfate on cancer patients with taste alterations caused by head and neck irradiation + (1 month after radiotherapy: patients in th … 1 month after radiotherapy: patients in the intervention arm had quicker recovery of taste acuity than the those in the placebo arm (with the exception of the NaCl detection threshold), up to total recovery of taste acuity with respect to basal time and the NaCl recognition threshold, and even an improvement in the HCl recognition thresholdprovement in the HCl recognition threshold)