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- Ehrenpreis et al. (2005): A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of Retinol Palmitate (Vitamin A) for Symptomatic Chronic Radiation Proctopathy + ('''Response rate after 90 days''' - interv … '''Response rate after 90 days'''</br>- intervention arm: 7/9</br>- placebo arm: 2/8</br>- p=0.057</br></br></br>Of the six patients who did not respond to placebo, five were enrolled in an open-label retinol palmitate treatment arm. All five of these met criteria for response to therapy.hese met criteria for response to therapy.)