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• Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects  + (In both arms most of the patients showed o … In both arms most of the patients showed only a slight increase of frequency of stools, change in the quality of bowel habits and rectal discomfort. 31.6% of the control-arm was observed to have diarrhoea. 11.7% in the enzyme-arm showed similar symptoms. 6 patients (3 per arm) showed bloody stools, perforations and fistulae. bloody stools, perforations and fistulae.)

• Dale et al. (2001): Co-medication with hydrolytic enzymes in radiation therapy of uterine cervix: evidence of the reduction of acute side effects  +