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- Ertekin et al. (2004): Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized study + (No statistically significant difference; w … No statistically significant difference;</br>weight loss increased as the week of radiotherapy advanced (Friedman chi-square test 40.42 p < 0.001); statistically significant difference in body weight measured before radiotherapy and the first day after radiotherapyotherapy and the first day after radiotherapy)